PDB: 644 resultsInfo pagesStatus searchChemie searchBIRD

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6PXL	3.74 Angstroms resolution structure of HlsU with an axial-channel plug Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, MAGNESIUM ION, ... Authors: Baytshtok, V, Grant, R.A, Sauer, R.T. Deposit date: 2019-07-26 Release date: 2020-07-29 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.741 Å) Cite: Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug. Cell Rep, 34, 2021
6PXK	3.65 Angstroms resolution structure of HslU with an axial-channel plug Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, SULFATE ION, ... Authors: Baytshtok, V, Grant, R.A, Sauer, R.T. Deposit date: 2019-07-26 Release date: 2020-07-29 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.647 Å) Cite: Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug. Cell Rep, 34, 2021
5OG1	Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state Descriptor: Chaperone protein ClpB,ATP-dependent Clp protease ATP-binding subunit ClpA,Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER Authors: Deville, C, Carroni, M, Franke, K.B, Topf, M, Bukau, B, Mogk, A, Saibil, H.R. Deposit date: 2017-07-11 Release date: 2017-08-16 Last modified: 2019-08-21 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase. Sci Adv, 3, 2017
5OFO	Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state, bound to the model substrate casein Descriptor: Chaperone protein ClpB,ATP-dependent Clp protease ATP-binding subunit ClpA,Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER Authors: Deville, C, Carroni, M, Franke, K.B, Topf, M, Bukau, B, Mogk, A, Saibil, H.R. Deposit date: 2017-07-11 Release date: 2017-08-16 Last modified: 2019-11-06 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase. Sci Adv, 3, 2017
1YYF	Correction of X-ray Intensities from an HslV-HslU co-crystal containing lattice translocation defects Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent hsl protease ATP-binding subunit hslU, ATP-dependent protease hslV Authors: Wang, J, Rho, S.H, Park, H.H, Eom, S.H. Deposit date: 2005-02-24 Release date: 2005-07-12 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (4.16 Å) Cite: Correction of X-ray intensities from an HslV-HslU co-crystal containing lattice-translocation defects. Acta Crystallogr.,Sect.D, 61, 2005
1XWI	Crystal Structure of VPS4B Descriptor: SKD1 protein, SULFATE ION Authors: Scott, A, Sundquist, W.I, Hill, C.P. Deposit date: 2004-11-01 Release date: 2005-10-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural and mechanistic studies of VPS4 proteins Embo J., 24, 2005
6CHS	Cdc48-Npl4 complex in the presence of ATP-gamma-S Descriptor: MAGNESIUM ION, Npl4, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Kim, K.H, Bodnar, N.O, Walz, T, Rapoport, T.A. Deposit date: 2018-02-22 Release date: 2018-07-04 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4. Nat. Struct. Mol. Biol., 25, 2018
6DJV	Mtb ClpB in complex with ATPgammaS and casein, Conformer 2 Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Yu, H.J, Li, H.L. Deposit date: 2018-05-26 Release date: 2018-09-26 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: ATP hydrolysis-coupled peptide translocation mechanism ofMycobacterium tuberculosisClpB. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DJU	Mtb ClpB in complex with ATPgammaS and casein, Conformer 1 Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Yu, H.J, Li, H.L. Deposit date: 2018-05-26 Release date: 2018-09-26 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: ATP hydrolysis-coupled peptide translocation mechanism ofMycobacterium tuberculosisClpB. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1OFI	Asymmetric complex between HslV and I-domain deleted HslU (H. influenzae) Descriptor: 4-IODO-3-NITROPHENYL ACETYL-LEUCINYL-LEUCINYL-LEUCINYL-VINYLSULFONE, ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ... Authors: Kwon, A.R, Kessler, B.M, Overkleeft, H.S, McKay, D.B. Deposit date: 2003-04-14 Release date: 2003-07-03 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structure and Reactivity of an Asymmetric Complex between Hslv and I-Domain Deleted Hslu, a Prokaryotic Homolog of the Eukaryotic Proteasome J.Mol.Biol., 330, 2003
1OFH	Asymmetric complex between HslV and I-domain deleted HslU (H. influenzae) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV, ... Authors: Kwon, A.R, Kessler, B.M, Overkleeft, H.S, McKay, D.B. Deposit date: 2003-04-14 Release date: 2003-07-03 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure and Reactivity of an Asymmetric Complex between Hslv and I-Domain Deleted Hslu, a Prokaryotic Homolog of the Eukaryotic Proteasome J.Mol.Biol., 330, 2003
7BPB	Human AAA+ ATPase VCP mutant - T76E, AMP-PNP bound form, Conformation I Descriptor: ADENOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase Authors: Yang, C, Zhang, H. Deposit date: 2020-03-22 Release date: 2021-03-31 Last modified: 2022-04-27 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle. Cell Death Differ., 2022
7BP9	Human AAA+ ATPase VCP mutant - T76E, ADP-bound form Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase Authors: Yang, C, Zhang, H. Deposit date: 2020-03-21 Release date: 2021-03-31 Last modified: 2022-04-27 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle. Cell Death Differ., 2022
7BP8	Human AAA+ ATPase VCP mutant - T76A, ADP-bound form Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase Authors: Yang, C, Zhang, H. Deposit date: 2020-03-21 Release date: 2021-03-31 Last modified: 2022-04-27 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle. Cell Death Differ., 2022
7BPA	Human AAA+ ATPase VCP mutant - T76A, AMP-PNP-bound form, Conformation I Descriptor: ADENOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase Authors: Yang, C, Zhang, H. Deposit date: 2020-03-21 Release date: 2021-03-31 Last modified: 2022-04-27 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle. Cell Death Differ., 2022
2ZAM	Crystal structure of mouse SKD1/VPS4B apo-form Descriptor: Vacuolar protein sorting-associating protein 4B Authors: Inoue, M, Kawasaki, M, Kamikubo, H, Kataoka, M, Kato, R, Yoshimori, T, Wakatsuki, S. Deposit date: 2007-10-08 Release date: 2008-10-07 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B Traffic, 9, 2008
8OOI	Full composite cryo-EM map of p97/VCP in ADP.Pi state Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Cheng, T.C, Sakata, E, Schuetz, A.K. Deposit date: 2023-04-05 Release date: 2024-01-31 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (2.61 Å) Cite: Characterizing ATP processing by the AAA+ protein p97 at the atomic level. Nat.Chem., 16, 2024
8RHN	Structure of the 55LCC ATPase complex Descriptor: ATPase family gene 2 protein homolog A, ATPase family gene 2 protein homolog B, Cyclin-dependent kinase 2-interacting protein, ... Authors: Foglizzo, M, Degtjarik, O, Zeqiraj, E. Deposit date: 2023-12-15 Release date: 2024-03-27 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity. Cell, 2024
8TH8	Linker domain of Nexin-dynein regulatory complex from Tetrahymena thermophila Descriptor: AAA family ATPase CDC48 subfamily protein, Calmodulin 7-2, Coiled-coil domain-containing protein 153, ... Authors: Ghanaeian, A.G, Bui, K.H. Deposit date: 2023-07-14 Release date: 2023-09-20 Last modified: 2023-09-27 Method: ELECTRON MICROSCOPY (7.4 Å) Cite: Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism. Nat Commun, 14, 2023
2ZAN	Crystal structure of mouse SKD1/VPS4B ATP-form Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Vacuolar protein sorting-associating protein 4B Authors: Inoue, M, Kawasaki, M, Kamikubo, H, Kataoka, M, Kato, R, Yoshimori, T, Wakatsuki, S. Deposit date: 2007-10-08 Release date: 2008-10-07 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3 Å) Cite: Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B Traffic, 9, 2008
8TID	Combined linker domain of N-DRC and associated proteins Tetrahymena Descriptor: AAA family ATPase CDC48 subfamily protein, CFAP20, Calmodulin 7-2, ... Authors: Ghanaeian, A.G, Majhi, S.M, McCaffrey, C.M, Nami, B.N, Black, C.B, Yang, S.K, Legal, T.L, Papoulas, O.P, Janowska, M.J, Valente-Paterno, M.V, Marcotte, E.M, Wloga, D.W, Bui, K.H. Deposit date: 2023-07-19 Release date: 2023-09-27 Last modified: 2024-04-03 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism. Nat Commun, 14, 2023
2ZAO	Crystal structure of mouse SKD1/VPS4B ADP-form Descriptor: ADENOSINE-5'-DIPHOSPHATE, Vacuolar protein sorting-associating protein 4B Authors: Inoue, M, Kawasaki, M, Kamikubo, H, Kataoka, M, Kato, R, Yoshimori, T, Wakatsuki, S. Deposit date: 2007-10-08 Release date: 2008-10-07 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B Traffic, 9, 2008
3B9P	Spastin Descriptor: CG5977-PA, isoform A, CHLORIDE ION Authors: Roll-Mecak, A, Vale, R.D. Deposit date: 2007-11-06 Release date: 2008-01-22 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin. Nature, 451, 2008
6WJN	SD-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... Authors: Chen, X, Walters, K.J. Deposit date: 2020-04-14 Release date: 2020-08-05 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (5.7 Å) Cite: Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome. Structure, 28, 2020
1QVR	Crystal Structure Analysis of ClpB Descriptor: ClpB protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PLATINUM (II) ION Authors: Lee, S, Sowa, M.E, Watanabe, Y, Sigler, P.B, Chiu, W, Yoshida, M, Tsai, F.T.F. Deposit date: 2003-08-28 Release date: 2003-10-21 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3 Å) Cite: The Structure of ClpB: A Molecular Chaperone that Rescues Proteins from an Aggregated State Cell(Cambridge,Mass.), 115, 2003

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