6PXL

3.74 Angstroms resolution structure of HlsU with an axial-channel plug

Summary for 6PXL

Entry DOI	10.2210/pdb6pxl/pdb
Descriptor	ATP-dependent protease ATPase subunit HslU, ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, ... (4 entities in total)
Functional Keywords	aaa+ atpase, peptidase, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	12
Total formula weight	616995.60
Authors	Baytshtok, V.,Grant, R.A.,Sauer, R.T. (deposition date: 2019-07-26, release date: 2020-07-29, Last modification date: 2023-11-15)
Primary citation	Baytshtok, V.,Fei, X.,Shih, T.T.,Grant, R.A.,Santos, J.C.,Baker, T.A.,Sauer, R.T. Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug. Cell Rep, 34:108639-108639, 2021 Cited by PubMed: 33472065 DOI: 10.1016/j.celrep.2020.108639 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.741 Å)

Structure validation