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2L5G
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BU of 2l5g by Molmil
Co-ordinates and 1H, 13C and 15N chemical shift assignments for the complex of GPS2 53-90 and SMRT 167-207
Descriptor: G protein pathway suppressor 2, Putative uncharacterized protein NCOR2
Authors:Oberoi, J, Yang, J, Neuhaus, D, Schwabe, J.W.R.
Deposit date:2010-11-01
Release date:2011-02-02
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery.
Nat.Struct.Mol.Biol., 18, 2011
5X8X
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BU of 5x8x by Molmil
Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain With Compound A.
Descriptor: (3R,4R)-4-[4-cyclopropyl-5-[3-(2-methylpropyl)cyclobutyl]-1,2,4-triazol-3-yl]-N-(2,4-dimethylphenyl)-1-ethanoyl-pyrrolidine-3-carboxamide, Nuclear receptor ROR-gamma, Nuclear receptor corepressor 2
Authors:Noguchi, M, Nomura, A, Murase, K, Doi, S, Yamaguchi, K, Adachi, T.
Deposit date:2017-03-03
Release date:2017-06-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Ternary complex of human ROR gamma ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment
Genes Cells, 22, 2017
2RT5
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BU of 2rt5 by Molmil
Structural insights into the recruitment of SMRT by the co-repressor SHARP under phosphorylative regulation
Descriptor: Msx2-interacting protein, peptide from Silencing mediator of retinoic acid and thyroid hormone receptor
Authors:Mikami, S, Kanaba, T, Mishima, M.
Deposit date:2013-04-22
Release date:2013-12-04
Last modified:2022-08-24
Method:SOLUTION NMR
Cite:Structural insights into the recruitment of SMRT by the corepressor SHARP under phosphorylative regulation.
Structure, 22, 2014
2GPV
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Estrogen Related Receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen and a SMRT peptide
Descriptor: 4-HYDROXYTAMOXIFEN, Estrogen-related receptor gamma, Nuclear receptor corepressor 2
Authors:Wang, L, Zuercher, W.J, Consler, T.G, Lambert, M.H, Miller, A.B, Osband-miller, L.A, McKee, D.D, Willson, T.M, Nolte, R.T.
Deposit date:2006-04-18
Release date:2006-09-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
J.Biol.Chem., 281, 2006
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