PDB: 219869 resultsInfo pagesStatus searchChemie searchBIRD

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8OYQ	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK13 Descriptor: Chemotaxis protein CheA, quinazolin-2-amine Authors: Adhav, A, Marina, A. Deposit date: 2023-05-05 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK13 To Be Published
8OYU	Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '2 up 1 down' RBD conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H6 nanobody, ... Authors: Weckener, M, Naismith, J.H, Owens, R.J. Deposit date: 2023-05-05 Release date: 2024-05-15 Method: ELECTRON MICROSCOPY (4 Å) Cite: Trimeric nanobodies potently neutralize Omicron variants of SARS-CoV-2 To Be Published
8OYZ	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK10 Descriptor: 2-azanyl-7,8-dihydro-6~{H}-quinazolin-5-one, Chemotaxis protein CheA Authors: Adhav, A, Marina, A. Deposit date: 2023-05-05 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK10 To Be Published
8OZ2	Human Aldose Reductase Mutant A299G/L300A in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid) Descriptor: Aldo-keto reductase family 1 member B1, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Klee, L.-S, Heine, A, Klebe, G. Deposit date: 2023-05-08 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.04 Å) Cite: Human Aldose Reductase Mutant A299G/L300A in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid) To Be Published
8OZ9	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound QUI-SV-383 Descriptor: 7-(1~{H}-1,2,3-triazol-5-yl)quinazolin-2-amine, Chemotaxis protein CheA Authors: Adhav, A, Marina, A. Deposit date: 2023-05-08 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound QUI-SV-383 To Be Published
8P7G	Structural characterization of PHOX2B and its DNA interactions shed lights into the molecular basis of the + 7Ala variant pathogenicity in CCHS Descriptor: Paired mesoderm homeobox protein 2B Authors: Russo, L, Diana, D, Fattorusso, R. Deposit date: 2023-05-30 Release date: 2024-05-15 Method: SOLUTION NMR Cite: Structural characterization of PHOX2B and its DNA interaction shed lights into the molecular basis of the + 7Ala variant pathogenicity in CCHS Chem Sci, 2024
8P9M	Hexameric Hfq from Chromobacterium haemolyticum Descriptor: GLYCEROL, RNA-binding protein Hfq Authors: Nikulin, A.D, Lekontseva, N.V. Deposit date: 2023-06-06 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (2 Å) Cite: The Structure of the Hfq Protein from Chromobacterium haemolyticum Revealed a New Variant of Regulation of RNA Binding with the Protein Crystallography Reports, 68, 2023
8PBO	Deep interactome learning for generative drug design Descriptor: 3-[2-fluoranyl-4-[3-[2-fluoranyl-4-(5-methyl-1,3,4-thiadiazol-2-yl)phenoxy]propoxy]phenyl]propanoic acid, GLYCEROL, Peroxisome proliferator-activated receptor gamma, ... Authors: Hakansson, M, Focht, D, Atz, K, Schneider, G. Deposit date: 2023-06-09 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Prospective de novo drug design with deep interactome learning. Nat Commun, 15, 2024
8POO	Low resolution structure of inactive conformation of the Ktr cation channel in presence of ATP and c-di-AMP Descriptor: Ktr system potassium uptake protein A, Ktr system potassium uptake protein B Authors: Cereija, T.B, Teixeira-Duarte, C.M, Morais-Cabral, J.H. Deposit date: 2023-07-05 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (5.77 Å) Cite: c-di-AMP determines the hierarchical organization of bacterial RCK proteins. Proc.Natl.Acad.Sci.USA, 121, 2024
8PPS	Dimeric RbdA EAL, in apo state Descriptor: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, EAL domain-containing protein, ... Authors: Cordery, C.R, Maly, M, Walsh, M.A, Tews, I. Deposit date: 2023-07-08 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Phosphodiesterase activation in the biofilm dispersal protein RbdA and relationship to the biofilm formation protein PA2072 of similar architecture To Be Published
8Q1G	LSD1-CoREST bound to Acetylated K14 of Histone H3 Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.3C, Lysine-specific histone demethylase 1A, ... Authors: Barone, M, Mattevi, A. Deposit date: 2023-07-31 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Uncoupling Histone Modification Crosstalk by Engineering Lysine Demethylase LSD1 To Be Published
8Q1H	LSD1 Y391K-CoREST bound to Histone H3 N-terminal tail Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.3C, Lysine-specific histone demethylase 1A, ... Authors: Barone, M, Mattevi, A. Deposit date: 2023-07-31 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Uncoupling Histone Modification Crosstalk by Engineering Lysine Demethylase LSD1 To Be Published
8Q1J	LSD1 Y391K-CoREST bound to Acetylated K14 of Histone H3 Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.3C, Lysine-specific histone demethylase 1A, ... Authors: Barone, M, Mattevi, A. Deposit date: 2023-07-31 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (2.87 Å) Cite: Uncoupling Histone Modification Crosstalk by Engineering Lysine Demethylase LSD1 To Be Published
8Q2O	Structure of alginate transporter AlgE from P. aeruginosa PAO1 by using Se-MAG for the the lipid cubic phase crystallization Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Alginate production protein AlgE, ... Authors: Huang, C.-Y, Boland, C, Kaki, S.S, Wang, M, Olieric, V, Caffrey, M. Deposit date: 2023-08-03 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Se-MAG Is a Convenient Additive for Experimental Phasing and Structure Determination of Membrane Proteins Crystallised by the Lipid Cubic Phase (In Meso) Method Crystals, 2023
8Q2P	Structure of the membrane integral lipoprotein N-acyltransferase Lnt from E. coli by using Se-MAG for the the lipid cubic phase crystallization Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, Apolipoprotein N-acyltransferase, ... Authors: Huang, C.-Y, Boland, C, Kaki, S.S, Wang, M, Olieric, V, Caffrey, M. Deposit date: 2023-08-03 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Se-MAG Is a Convenient Additive for Experimental Phasing and Structure Determination of Membrane Proteins Crystallised by the Lipid Cubic Phase (In Meso) Method Crystals, 2023
8Q50	Nitrogenase Fe protein from Methanothermococcus thermolithotrophicus, tetragonal crystalline form at 1.91-A resolution Descriptor: ACETATE ION, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... Authors: Maslac, N, Wagner, T. Deposit date: 2023-08-07 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Structural comparison of (hyper-)thermophilic nitrogenase reductases from three marine Methanococcales. Febs J., 2024
8Q5T	Nitrogenase Fe protein from Methanothermococcus thermolithotrophicus, monoclinic crystalline form at 2.31-A resolution Descriptor: GLYCEROL, IRON/SULFUR CLUSTER, Nitrogenase iron protein 1 Authors: Maslac, N, Wagner, T. Deposit date: 2023-08-09 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Structural comparison of (hyper-)thermophilic nitrogenase reductases from three marine Methanococcales. Febs J., 2024
8Q5V	MgADP-bound Fe protein of the molybdenum nitrogenase from Methanothermococcus thermolithotrophicus Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... Authors: Maslac, N, Wagner, T. Deposit date: 2023-08-09 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (2.74 Å) Cite: Structural comparison of (hyper-)thermophilic nitrogenase reductases from three marine Methanococcales. Febs J., 2024
8Q5W	MgADP-bound Fe protein of the molybdenum nitrogenase from Methanocaldococcus infernus Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... Authors: Maslac, N, Wagner, T. Deposit date: 2023-08-09 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Structural comparison of (hyper-)thermophilic nitrogenase reductases from three marine Methanococcales. Febs J., 2024
8Q5X	MgADP-bound Fe protein of the molybdenum nitrogenase from Methanococcus maripaludis Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... Authors: Maslac, N, Wagner, T. Deposit date: 2023-08-09 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural comparison of (hyper-)thermophilic nitrogenase reductases from three marine Methanococcales. Febs J., 2024
8Q8H	Crystal Structure of Apo beta-D-GalNAcase from Niabella aurantiaca (Structure 2) Descriptor: SODIUM ION, SULFATE ION, beta-D-GalNAcase from Niabella aurantiaca DSM 17617 Authors: Morth, J.P, Moreno Prieto, E.S, Siebenhaar, S. Deposit date: 2023-08-18 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Characterization and structural study of a novel beta-N-acetylgalactosaminidase from Niabella aurantiaca. Febs J., 291, 2024
8QBN	Structure of the non-canonical CTLH E3 substrate receptor WDR26 bound to YPEL5 Descriptor: Protein yippee-like 5, WD repeat-containing protein 26, ZINC ION Authors: Chrustowicz, J, Sherpa, D, Schulman, B.A. Deposit date: 2023-08-24 Release date: 2024-05-15 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Non-canonical substrate targeting by the supramolecular CTLH E3 ligase reveals an WDR26-YPEL5 regulatory module To Be Published
8QE8	Structure of the non-canonical CTLH E3 substrate receptor WDR26 bound to NMNAT1 substrate Descriptor: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1, WD repeat-containing protein 26, ... Authors: Chrustowicz, J, Sherpa, D, Schulman, B.A. Deposit date: 2023-08-30 Release date: 2024-05-15 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Non-canonical substrate targeting by the supramolecular CTLH E3 ligase reveals an WDR26-YPEL5 regulatory module To Be Published
8QFY	Crystal structure of high affinity TCR in complex with pHLA harbouring bacterial peptide Descriptor: ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... Authors: Pengelly, R.J, Robinson, R.A. Deposit date: 2023-09-05 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (2.33 Å) Cite: An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 121, 2024
8QRE	Cholera holotoxin (wildtype) Descriptor: ACETATE ION, Cholera enterotoxin subunit A, Cholera enterotoxin subunit B, ... Authors: Mojica, N, Cordara, G, Krengel, U. Deposit date: 2023-10-06 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Using Vibrio natriegens for High-Yield Production of Challenging Expression Targets and for Protein Perdeuteration. Biochemistry, 63, 2024

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