PDB: 220113 件ウェブページステータス検索Chemie searchBIRD

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9BHR	Crystal structure of the WDR domain of human DCAF1 in complex with OICR-40155 compound 分子名称: (4P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-4-(4-chloro-2-fluorophenyl)-5-{(1E)-3-[(2-methoxyethyl)amino]-3-oxoprop-1-en-1-yl}-1H-pyrrole-3-carboxamide, DDB1- and CUL4-associated factor 1 著者 kimani, S, Dong, A, Li, Y, Seitova, A, Al-Awar, R, Krausser, C, Wilson, B, Ackloo, S, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) 登録日 2024-04-21 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Crystal structure of the WDR domain of human DCAF1 in complex with OICR-40155 compound To be published
9BHA	Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology annealed conformation 分子名称: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang 著者 Zerio, C.J, Lander, G.C. 登録日 2024-04-19 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Human polymerase theta helicase positions DNA microhomologies for double-strand break repair To Be Published
9BH9	Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology aligning conformation 分子名称: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang 著者 Zerio, C.J, Lander, G.C. 登録日 2024-04-19 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Human polymerase theta helicase positions DNA microhomologies for double-strand break repair To Be Published
9BH8	Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology searching conformation 分子名称: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang 著者 Zerio, C.J, Lander, G.C. 登録日 2024-04-19 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Human polymerase theta helicase positions DNA microhomologies for double-strand break repair To Be Published
9BH7	Human DNA polymerase theta helicase domain dimer in the apo form 分子名称: DNA polymerase theta 著者 Zerio, C.J, Lander, G.C. 登録日 2024-04-19 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Human polymerase theta helicase positions DNA microhomologies for double-strand break repair To Be Published
9BH6	Human DNA polymerase theta helicase domain tetramer in the apo form 分子名称: DNA polymerase theta 著者 Zerio, C.J, Lander, G.C. 登録日 2024-04-19 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Human polymerase theta helicase positions DNA microhomologies for double-strand break repair To Be Published
9BFT	Cryo-EM co-structure of AcrB with CU244 分子名称: (2S)-1-{[(1R,5R)-3-azabicyclo[3.1.0]hexan-6-yl]amino}-3-(3,5-dichlorophenoxy)propan-2-ol, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Multidrug efflux pump subunit AcrB 著者 Su, C.C. 登録日 2024-04-18 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.44 Å) 主引用文献 Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023
9BFN	Cryo-EM co-structure of AcrB with the CU232 efflux pump inhibitor 分子名称: (2R)-1-(4-aminopiperidin-1-yl)-3-[3-(trifluoromethyl)phenoxy]propan-2-ol, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Multidrug efflux pump subunit AcrB 著者 Su, C.C. 登録日 2024-04-18 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.71 Å) 主引用文献 Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023
9BFM	Cryo-EM co-structure of AcrB with the EPM35 efflux pump inhibitor 分子名称: (2S)-1-(3,4-dichlorophenoxy)-3-(4-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}piperidin-1-yl)propan-2-ol, Multidrug efflux pump subunit AcrB 著者 Su, C.C. 登録日 2024-04-18 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.71 Å) 主引用文献 Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023
9BFH	Cryo-EM co-structure of AcrB with the CU032 efflux pump inhibitor 分子名称: (2S)-1-[(3R)-3-aminopyrrolidin-1-yl]-3-(3,4-dichlorophenoxy)propan-2-ol, Multidrug efflux pump subunit AcrB 著者 Su, C.C. 登録日 2024-04-17 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.62 Å) 主引用文献 Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023
9BEI	Cryo-EM structure of synthetic claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain, sFab COP-2, and Nanobody 分子名称: Anti-fab nanobody, COP-2 Fab Heavy chain, COP-2 Fab Light chain, ... 著者 Vecchio, A.J. 登録日 2024-04-15 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (4.16 Å) 主引用文献 Computational design of soluble functional analogues of integral membrane proteins To be published
9BE2	Structure of the E. coli nucleic associated protein, YejK 分子名称: Nucleoid-associated protein YejK 著者 Schumacher, M.A. 登録日 2024-04-13 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (3.56 Å) 主引用文献 Structure of the E. coli nucleic associated protein, YejK To Be Published
9BDX	NF-kappaB RelA homo-dimer bound to CG-centric kappaB DNA 分子名称: DNA (5'-D(*AP*TP*CP*AP*CP*TP*GP*GP*AP*AP*GP*TP*TP*CP*CP*CP*AP*GP*T)-3'), DNA (5'-D(P*AP*CP*TP*GP*GP*GP*AP*AP*CP*TP*TP*CP*CP*AP*GP*TP*GP*AP*T)-3'), Transcription factor p65 著者 Biswas, T, Shahabi, S, Tsodikov, O.V, Ghosh, G. 登録日 2024-04-12 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Transient interactions modulate affinity of NF-kappaB transcription factors for DNA To Be Published
9BDW	NF-kappaB RelA homo-dimer bound to GC-centric kappaB DNA 分子名称: DNA (5'-D(P*AP*CP*TP*GP*GP*GP*AP*AP*GP*TP*TP*CP*CP*AP*GP*TP*GP*AP*T)-3'), DNA (5'-D(P*AP*TP*CP*AP*CP*TP*GP*GP*AP*AP*CP*TP*TP*CP*CP*CP*AP*GP*T)-3'), SULFATE ION, ... 著者 Biswas, T, Shahabi, S, Tsodikov, O.V, Huang, D, Ghosh, G. 登録日 2024-04-12 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Transient interactions modulate affinity of NF-kappaB transcription factors for DNA To Be Published
9BDV	NF-kappaB RelA homo-dimer bound to TA-centric kappaB DNA 分子名称: DNA (5'-D(*AP*TP*CP*AP*CP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*CP*AP*GP*T)-3'), DNA (5'-D(P*AP*CP*TP*GP*GP*GP*AP*AP*TP*TP*TP*CP*CP*AP*GP*TP*GP*AP*T)-3'), SULFATE ION, ... 著者 Biswas, T, Shahabi, S, Tsodikov, O.V. 登録日 2024-04-12 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Transient interactions modulate affinity of NF-kappaB transcription factors for DNA To Be Published
9BDU	NF-kappaB RelA homo-dimer bound to AT-centric kappaB DNA 分子名称: DNA (5'-D(P*AP*CP*TP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*AP*GP*TP*GP*AP*T)-3'), DNA (5'-D(P*AP*TP*CP*AP*CP*TP*GP*GP*AP*AP*TP*TP*TP*CP*CP*CP*AP*GP*T)-3'), SULFATE ION, ... 著者 Biswas, T, Huang, D, Ghosh, G. 登録日 2024-04-12 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Transient interactions modulate affinity of NF-kappaB transcription factors for DNA To Be Published
9BCZ	Chicken 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (PLCZ1) in complex with calcium and phosphorylated threonine 分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Edwards, M.M, Dong, A, Theo-Emegano, N, Seitova, A, Loppnau, P, Leung, R, Li, H, Ilyassov, O, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium, Structural Genomics Consortium (SGC) 登録日 2024-04-10 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Chicken 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (PLCZ1) in complex with calcium and phosphorylated threonine To be published
9BCB	Crystal structure of human cellular retinol binding protein 3 in complex with C11 TopFluor MG 分子名称: 1-[11-(dipyrrometheneboron difluoride)undecanoyl]-rac-glycerol, GLYCEROL, Retinol-binding protein 5 著者 Golczak, M. 登録日 2024-04-08 公開日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Interactom of cellular retinol binding protein 3. To Be Published
9BBM	PHF filament generated from 4E-Tau(297-407) under neutral Mg2+ condition 分子名称: Isoform Tau-F of Microtubule-associated protein tau 著者 Duan, P, El Mammeri, N. 登録日 2024-04-06 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Milligram-Scale Assembly and NMR Fingerprint of Tau Fibrils Adopting the Alzheimer's Disease Fold. J.Biol.Chem., 2024
9BBL	THF filament generated from 4E-Tau(297-407) under neutral Mg2+ condition 分子名称: Isoform Tau-F of Microtubule-associated protein tau 著者 Duan, P, El Mammeri, N. 登録日 2024-04-06 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Milligram-Scale Assembly and NMR Fingerprint of Tau Fibrils Adopting the Alzheimer's Disease Fold. J.Biol.Chem., 2024
9B94	Cryo-EM structure of the E396A mutant of human TRPM4 in complex with calcium at 37 degrees Celsius 分子名称: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4 著者 Hu, J, Lu, W, Du, J. 登録日 2024-04-01 公開日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Physiological temperature drives TRPM4 ligand recognition and gating Nature, 2024
9B93	Cryo-EM structure of the human TRPM4 channel in the presence of EDTA at 37 degrees Celsius 分子名称: Transient receptor potential cation channel subfamily M member 4 著者 Hu, J, Lu, W, Du, J. 登録日 2024-04-01 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Physiological temperature drives TRPM4 ligand recognition and gating Nature, 2024
9B92	Cryo-EM structure of the human TRPM4 in complex with calcium at 18 degrees Celsius 分子名称: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4 著者 Hu, J, Lu, W, Du, J. 登録日 2024-04-01 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Physiological temperature drives TRPM4 ligand recognition and gating Nature, 2024
9B91	Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and ATP at 37 degrees Celsius 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Transient receptor potential cation channel subfamily M member 4 著者 Hu, J, Lu, W, Du, J. 登録日 2024-04-01 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Physiological Temperature Drives TRPM4 Ligand Recognition and Gating Nature, 2024
9B90	Cryo-EM structure of the human TRPM4 channel in complex with calcium and ATP at 37 degrees Celsius 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Transient receptor potential cation channel subfamily M member 4 著者 Hu, J, Lu, W, Du, J. 登録日 2024-04-01 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Physiological Temperature Drives TRPM4 Ligand Recognition and Gating Nature, 2024

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