4V97
| Crystal structure of the bacterial ribosome ram mutation G299A. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Fagan, C.E, Dunkle, J.A, Maehigashi, T, Dunham, C.M. | 登録日 | 2012-04-06 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.516 Å) | 主引用文献 | Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4V5L
| The structure of EF-Tu and aminoacyl-tRNA bound to the 70S ribosome with a GTP analog | 分子名称: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Voorhees, R.M, Schmeing, T.M, Ramakrishnan, V. | 登録日 | 2010-09-02 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The Mechanism for Activation of GTP Hydrolysis on the Ribosome. Science, 330, 2010
|
|
4V8J
| Crystal structure of the bacterial ribosome ram mutation G347U. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Fagan, C.E, Dunkle, J.A, Maehigashi, T, Dunham, C.M. | 登録日 | 2011-12-20 | 公開日 | 2014-07-09 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
2F4S
| A-site RNA in complex with neamine | 分子名称: | (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside, 5'-R(P*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3' | 著者 | Murray, J.B, Meroueh, S.O, Russell, R.J, Lentzen, G, Haddad, J, Mobashery, S. | 登録日 | 2005-11-24 | 公開日 | 2006-05-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site Chem.Biol., 13, 2006
|
|
6MPI
| Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGU-codon in the A-site and paromomycin | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Cantara, W.A, DeMirci, H, Agris, P.F. | 登録日 | 2018-10-07 | 公開日 | 2019-04-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.33 Å) | 主引用文献 | A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432, 2020
|
|
6MKN
| Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Cantara, W.A, DeMirci, H, Agris, P.F. | 登録日 | 2018-09-25 | 公開日 | 2019-04-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | 主引用文献 | A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432, 2020
|
|
6MPF
| Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGC-codon in the A-site and paromomycin | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Cantara, W.A, DeMirci, H, Agris, P.F. | 登録日 | 2018-10-05 | 公開日 | 2019-04-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.33 Å) | 主引用文献 | A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432, 2020
|
|
6OF6
| Crystal structure of tRNA^ Ala(GGC) bound to cognate 70S A-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Nguyen, H.A, Sunita, S, Dunham, C.M. | 登録日 | 2019-03-28 | 公開日 | 2020-06-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Disruption of evolutionarily correlated tRNA elements impairs accurate decoding. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6OPE
| Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to near-cognate 70S A site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Nguyen, H.A, Sunita, S, Dunham, C.M. | 登録日 | 2019-04-24 | 公開日 | 2020-06-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Disruption of evolutionarily correlated tRNA elements impairs accurate decoding. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6ORD
| Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to cognate 70S A site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Nguyen, H.A, Sunita, S, Dunham, C.M. | 登録日 | 2019-04-30 | 公開日 | 2020-06-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Disruption of evolutionarily correlated tRNA elements impairs accurate decoding. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6OJ2
| Crystal structure of tRNA^ Ala(GGC) bound to the near-cognate 70S A-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Nguyen, H.A, Sunita, S, Dunham, C.M. | 登録日 | 2019-04-10 | 公開日 | 2020-06-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Disruption of evolutionarily correlated tRNA elements impairs accurate decoding. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
3Q2J
| Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa Protein Kinase Inhibitor CKI-7 Complex | 分子名称: | Aminoglycoside 3'-phosphotransferase, CALCIUM ION, N-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE | 著者 | Fong, D.H, Xiong, B, Hwang, J, Berghuis, A.M. | 登録日 | 2010-12-20 | 公開日 | 2011-05-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1501 Å) | 主引用文献 | Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor. Plos One, 6, 2011
|
|
3TM0
| Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa AMPPNP Butirosin A Complex | 分子名称: | (2S)-4-amino-N-[(1R,2S,3R,4R,5S)-5-amino-4-[(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxy-3-(beta-D-xylofuranosyloxy)cyclohexyl]-2-hydroxybutanamide, Aminoglycoside 3'-phosphotransferase, MAGNESIUM ION, ... | 著者 | Berghuis, A.M, Fong, D.H. | 登録日 | 2011-08-30 | 公開日 | 2011-10-19 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of APH(3')-IIIa-mediated resistance to N1-substituted aminoglycoside antibiotics. Antimicrob.Agents Chemother., 53, 2009
|
|
6MB4
| Binary (sisomicin) structure of AAC-IIIb | 分子名称: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, Aac(3)-IIIb protein | 著者 | Cuneo, M.J, Kumar, P. | 登録日 | 2018-08-29 | 公開日 | 2018-11-07 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | 主引用文献 | Encoding of Promiscuity in an Aminoglycoside Acetyltransferase. J. Med. Chem., 61, 2018
|
|
6MB6
| AAC-IIIb binary with CoASH | 分子名称: | Aac(3)-IIIb protein, COENZYME A, MALONATE ION | 著者 | Cuneo, M.J, Kumar, P. | 登録日 | 2018-08-29 | 公開日 | 2018-11-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Encoding of Promiscuity in an Aminoglycoside Acetyltransferase. J. Med. Chem., 61, 2018
|
|
6MB8
| Apo structure of AAC-IIIb | 分子名称: | Aac(3)-IIIb protein, CHLORIDE ION | 著者 | Cuneo, M.J, Kumar, P. | 登録日 | 2018-08-29 | 公開日 | 2018-11-07 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Encoding of Promiscuity in an Aminoglycoside Acetyltransferase. J. Med. Chem., 61, 2018
|
|
5DV2
| |
1KD3
| The Crystal Structure of r(GGUCACAGCCC)2, Thallium form | 分子名称: | 5'-R(*GP*GP*UP*CP*AP*CP*AP*GP*CP*CP*C)-3', THALLIUM (I) ION | 著者 | Kacer, V, Scaringe, S.A, Scarsdale, J.N, Rife, J.P. | 登録日 | 2001-11-12 | 公開日 | 2003-03-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structures of r(GGUCACAGCCC)2. Acta Crystallogr.,Sect.D, 59, 2003
|
|
1KD5
| The Crystal Structure of r(GGUCACAGCCC)2 metal free form | 分子名称: | 5'-R(*GP*GP*UP*CP*AP*CP*AP*GP*CP*CP*C)-3' | 著者 | Kacer, V, Scaringe, S.A, Scarsdale, J.N, Rife, J.P. | 登録日 | 2001-11-12 | 公開日 | 2003-03-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Crystal structures of r(GGUCACAGCCC)2. Acta Crystallogr.,Sect.D, 59, 2003
|
|
2BKK
| Crystal structure of Aminoglycoside Phosphotransferase APH(3')-IIIa in complex with the inhibitor AR_3a | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE, DESIGNED ANKYRIN REPEAT INHIBITOR AR_3A, ... | 著者 | Kohl, A, Amstutz, P, Parizek, P, Binz, H.K, Briand, C, Capitani, G, Forrer, P, Pluckthun, A, Grutter, M.G. | 登録日 | 2005-02-16 | 公開日 | 2005-08-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Allosteric Inhibition of Aminoglycoside Phosphotransferase by a Designed Ankyrin Repeat Protein Structure, 13, 2005
|
|
1P6V
| Crystal structure of the tRNA domain of transfer-messenger RNA in complex with SmpB | 分子名称: | 45-MER, SsrA-binding protein | 著者 | Gutmann, S, Haebel, P.W, Metzinger, L, Sutter, M, Felden, B, Ban, N. | 登録日 | 2003-04-30 | 公開日 | 2003-08-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of the transfer-RNA domain of transfer-messenger RNA in complex with SmpB Nature, 424, 2003
|
|
8VTS
| |
7LLD
| Crystal structure of GenB4 in complex with external aldimine of PLP-sisomicin | 分子名称: | (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-amino-2,3,4,6-tetradeoxy-6-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-alpha-D-erythro-hexopyranoside, (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-amino-2,3,4,6-tetradeoxy-6-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-beta-L-threo-hexopyranoside, C-6' aminotransferase, ... | 著者 | Bury, P.S, Huang, F, Leadlay, P.F, Dias, M.V.B. | 登録日 | 2021-02-03 | 公開日 | 2021-09-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structure of GenB4 in complex with external aldimine of PLP-sisomicin Acs Catalysis, 2021
|
|
7LLE
| |
5VQF
| Crystal Structure of pro-TGF-beta 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Transforming growth factor beta-1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Zhao, B, Xu, S, Dong, X, Lu, C, Springer, T.A. | 登録日 | 2017-05-08 | 公開日 | 2017-11-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Prodomain-growth factor swapping in the structure of pro-TGF-beta 1. J. Biol. Chem., 293, 2018
|
|