1ZBH
| 3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease | Descriptor: | 3'-5' exonuclease ERI1, 5'-R(*CP*CP*GP*GP*CP*UP*CP*UP*UP*UP*UP*CP*AP*GP*AP*GP*CP*CP*GP*G)-3', ADENOSINE MONOPHOSPHATE, ... | Authors: | Cheng, Y, Patel, D.J. | Deposit date: | 2005-04-08 | Release date: | 2006-09-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for 3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease, a human nuclease that also targets siRNA To be Published
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1ZBU
| crystal structure of full-length 3'-exonuclease | Descriptor: | 3'-5' exonuclease ERI1, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION | Authors: | Cheng, Y, Patel, D.J. | Deposit date: | 2005-04-08 | Release date: | 2006-09-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.998 Å) | Cite: | Structural basis for 3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease, a human nuclease that also targets siRNA To be Published
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4RBY
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4RC0
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4RBZ
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4O41
| Amide linked RNA | Descriptor: | AMIDE LINKED RNA, STRONTIUM ION | Authors: | Pallan, P.S, Egli, M. | Deposit date: | 2013-12-18 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs. Nucleic Acids Res., 42, 2014
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6WXQ
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2X1O
| Gelsolin Nanobody | Descriptor: | GELSOLIN NANOBODY | Authors: | Van Den Abbeele, A, Declercq, S, De Ganck, A, De Corte, V, Van Loo, B, Srinivasan, V, Steyaert, J, Van De Kerckhove, J, Gettemans, J. | Deposit date: | 2010-01-03 | Release date: | 2011-01-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction. Cell.Mol.Life Sci., 67, 2010
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3TIX
| Crystal structure of the Chp1-Tas3 complex core | Descriptor: | CHLORIDE ION, Chromo domain-containing protein 1, POTASSIUM ION, ... | Authors: | Schalch, T, Joshua-Tor, L. | Deposit date: | 2011-08-22 | Release date: | 2011-11-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9001 Å) | Cite: | The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS. Nat.Struct.Mol.Biol., 18, 2011
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2X1Q
| Gelsolin Nanobody | Descriptor: | GELSOLIN NANOBODY | Authors: | Van Den Abbeele, A, Declercq, S, De Ganck, A, De Corte, V, Van Loo, B, Srinivasan, V, Steyaert, J, Van De Kerckhove, J, Gettemans, J. | Deposit date: | 2010-01-03 | Release date: | 2011-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.06 Å) | Cite: | A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction. Cell.Mol.Life Sci., 67, 2010
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2X1P
| Gelsolin Nanobody | Descriptor: | GELSOLIN NANOBODY | Authors: | Van Den Abbeele, A, Declercq, S, De Ganck, A, De Corte, V, Van Loo, B, Srinivasan, V, Steyaert, J, Van De Kerckhove, J, Gettemans, J. | Deposit date: | 2010-01-03 | Release date: | 2011-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction. Cell.Mol.Life Sci., 67, 2010
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1YTU
| Structural basis for 5'-end-specific recognition of the guide RNA strand by the A. fulgidus PIWI protein | Descriptor: | 5'-R(P*AP*GP*AP*CP*AP*G)-3', 5'-R(P*UP*GP*UP*C)-3', MAGNESIUM ION, ... | Authors: | Ma, J.B, Yuan, Y.R, Meister, G, Pei, Y, Tuschl, T, Patel, D.J. | Deposit date: | 2005-02-11 | Release date: | 2005-04-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature, 434, 2005
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4OLB
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4OLA
| Crystal Structure of Human Argonaute2 | Descriptor: | 5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*U)-3', ISOPROPYL ALCOHOL, PHENOL, ... | Authors: | Schirle, N.T, MacRae, I.J. | Deposit date: | 2014-01-23 | Release date: | 2014-02-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of human Argonaute2. Science, 336, 2012
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4WYQ
| Crystal structure of the Dicer-TRBP interface | Descriptor: | Endoribonuclease Dicer, Poly(UNK), RISC-loading complex subunit TARBP2 | Authors: | Wilson, R.C, Doudna, J.A. | Deposit date: | 2014-11-18 | Release date: | 2014-12-17 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Dicer-TRBP Complex Formation Ensures Accurate Mammalian MicroRNA Biogenesis. Mol.Cell, 57, 2015
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5W6V
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5JRE
| Crystal structure of NeC3PO in complex with ssDNA. | Descriptor: | 9-METHYL-9H-PURIN-6-AMINE, ADENINE, NEQ131, ... | Authors: | Gan, J, Zhang, J. | Deposit date: | 2016-05-06 | Release date: | 2016-09-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for single-stranded RNA recognition and cleavage by C3PO Nucleic Acids Res., 44, 2016
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5JRC
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5JR9
| Crystal structure of apo-NeC3PO | Descriptor: | NEQ131 | Authors: | Zhang, J, Gan, J. | Deposit date: | 2016-05-06 | Release date: | 2016-09-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for single-stranded RNA recognition and cleavage by C3PO Nucleic Acids Res., 44, 2016
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7Y8P
| Crystal structure of 4'-selenoRNA duplex | Descriptor: | COBALT HEXAMMINE(III), RNA (5'-R(*GP*GP*AP*(IKS)P*(ILK)P*(IKS)P*GP*AP*GP*UP*CP*C)-3') | Authors: | Kondo, J, Minakawa, N, Ohta, M, Takahashi, H, Tarashima, N. | Deposit date: | 2022-06-24 | Release date: | 2023-05-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Synthesis and properties of fully-modified 4'-selenoRNA, an endonuclease-resistant RNA analog. Bioorg.Med.Chem., 76, 2022
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3VEM
| Structural basis of transcriptional gene silencing mediated by Arabidopsis MOM1 | Descriptor: | Helicase protein MOM1 | Authors: | Nishikura, T, Petty, T.J, Halazonetis, T, Paszkowski, J, Thore, S. | Deposit date: | 2012-01-09 | Release date: | 2012-03-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural Basis of Transcriptional Gene Silencing Mediated by Arabidopsis MOM1. PLOS GENET., 8, 2012
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3PJA
| Crystal structure of human C3PO complex | Descriptor: | Translin, Translin-associated protein X | Authors: | Huang, N, Zhang, H. | Deposit date: | 2010-11-09 | Release date: | 2011-05-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of C3PO and mechanism of human RISC activation. Nat.Struct.Mol.Biol., 18, 2011
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3QB5
| Human C3PO complex in the presence of MnSO4 | Descriptor: | CHLORIDE ION, MANGANESE (II) ION, PHOSPHATE ION, ... | Authors: | Ye, X, Huang, N, Liu, Y, Paroo, Z, Chen, S, Zhang, H, Liu, Q. | Deposit date: | 2011-01-12 | Release date: | 2011-05-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of C3PO and mechanism of human RISC activation. Nat.Struct.Mol.Biol., 18, 2011
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8D1V
| Cryo-EM structure of guide RNA and target RNA bound Cas7-11 | Descriptor: | CRISPR RNA (34-MER), CRISPR-associated RAMP family protein, SS target RNA (5'-R(P*AP*GP*CP*UP*UP*GP*GP*UP*UP*CP*AP*AP*AP*GP*AP*AP*CP*G)-3'), ... | Authors: | Rai, J, Goswami, H, Li, H. | Deposit date: | 2022-05-27 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (2.82 Å) | Cite: | Molecular mechanism of active Cas7-11 in processing CRISPR RNA and interfering target RNA. Elife, 11, 2022
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4TXD
| Crystal structure of Thermofilum pendens Csc2 | Descriptor: | Csc2, ZINC ION | Authors: | Hrle, A, Conti, E. | Deposit date: | 2014-07-03 | Release date: | 2014-08-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.818 Å) | Cite: | Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family. Rna Biol., 11, 2014
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