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1KKB
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BU of 1kkb by Molmil
Complex of Escherichia coli Adenylosuccinate Synthetase with IMP and Hadacidin
Descriptor: Adenylosuccinate Synthetase, HADACIDIN, INOSINIC ACID
Authors:Hou, Z, Wang, W, Fromm, H.J, Honzatko, R.B.
Deposit date:2001-12-06
Release date:2002-03-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:IMP Alone Organizes the Active Site of Adenylosuccinate Synthetase from Escherichia coli.
J.Biol.Chem., 277, 2002
8H77
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BU of 8h77 by Molmil
Hsp90-AhR-p23-XAP2 complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ...
Authors:Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F.
Deposit date:2022-10-19
Release date:2023-01-04
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the cytosolic AhR complex.
Structure, 31, 2023
6GZ3
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BU of 6gz3 by Molmil
tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-1 (TI-POST-1)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Flis, J, Holm, M, Rundlet, E.J, Loerke, J, Hilal, T, Dabrowski, M, Buerger, J, Mielke, T, Blanchard, S.C, Spahn, C.M.T, Budkevich, T.V.
Deposit date:2018-07-03
Release date:2018-12-05
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis.
Cell Rep, 25, 2018
1RMD
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BU of 1rmd by Molmil
RAG1 DIMERIZATION DOMAIN
Descriptor: RAG1, ZINC ION
Authors:Bellon, S.F, Rodgers, K.K, Schatz, D.G, Coleman, J.E, Steitz, T.A.
Deposit date:1997-01-10
Release date:1997-07-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster.
Nat.Struct.Biol., 4, 1997
6JKY
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BU of 6jky by Molmil
Crystal structure of MvcA-UBE2N-Ub complex from Legionella pneumophila
Descriptor: MvcA, Ub, Ubiquitin-conjugating enzyme E2 N
Authors:Ouyang, S.Y, Guan, H.
Deposit date:2019-03-03
Release date:2019-12-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.454 Å)
Cite:Legionella pneumophila regulates the activity of UBE2N by deamidase-mediated deubiquitination.
Embo J., 39, 2020
8AMS
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BU of 8ams by Molmil
Complex of human TRIM2 RING domain, UBCH5C, and Ubiquitin
Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, GLYCEROL, Polyubiquitin-C, ...
Authors:Perez-Borrajero, C, Kotova, I, Murciano, B, Hennig, J.
Deposit date:2022-08-04
Release date:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and biophysical studies of TRIM2 and TRIM3
To Be Published
7UN6
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BU of 7un6 by Molmil
Complex of UBE2O with NAP1L1
Descriptor: (E3-independent) E2 ubiquitin-conjugating enzyme, Nucleosome assembly protein 1-like 1
Authors:Yip, M.C.J, Sedor, S.F, Shao, S.
Deposit date:2022-04-09
Release date:2022-08-03
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism of client selection by the protein quality-control factor UBE2O.
Nat.Struct.Mol.Biol., 29, 2022
7UN3
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BU of 7un3 by Molmil
Complex of UBE2O with NAP1L1 and ubiquitylated uL2
Descriptor: Nucleosome assembly protein 1-like 1, Ubiquitin,60S ribosomal protein L8,(E3-independent) E2 ubiquitin-conjugating enzyme fusion
Authors:Yip, M.C.J, Sedor, S.F, Shao, S.
Deposit date:2022-04-08
Release date:2022-08-03
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanism of client selection by the protein quality-control factor UBE2O.
Nat.Struct.Mol.Biol., 29, 2022
1X23
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BU of 1x23 by Molmil
Crystal structure of ubch5c
Descriptor: Ubiquitin-conjugating enzyme E2 D3
Authors:Nakanishi, M, Teshima, N, Mizushima, T, Murata, S, Tanaka, K, Yamane, T.
Deposit date:2005-04-19
Release date:2005-05-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of ubch5c
To be Published
6ZQH
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BU of 6zqh by Molmil
Yeast Uba1 in complex with ubiquitin
Descriptor: BETA-MERCAPTOETHANOL, GLYCEROL, TETRAETHYLENE GLYCOL, ...
Authors:Misra, M, Schindelin, H.
Deposit date:2020-07-09
Release date:2020-11-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.032 Å)
Cite:Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection.
Chemistry, 27, 2021
6EXN
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BU of 6exn by Molmil
Post-catalytic P complex spliceosome with 3' splice site docked
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat: UBC4 RNA, ...
Authors:Wilkinson, M.E, Fica, S.M, Galej, W.P, Norman, C.M, Newman, A.J, Nagai, K.
Deposit date:2017-11-08
Release date:2018-01-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.
Science, 358, 2017
8QMO
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BU of 8qmo by Molmil
Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ...
Authors:Kwong, H.S, Grandvuillemin, L, Sirounian, S, Ancelin, A, Lai-Kee-Him, J, Carivenc, C, Lancey, C, Ragan, T.J, Hesketh, E.L, Bourguet, W, Gruszczyk, J.
Deposit date:2023-09-24
Release date:2024-01-10
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related Compounds.
J.Mol.Biol., 436, 2024
3H0Q
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BU of 3h0q by Molmil
Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 3
Descriptor: 4-({4-[(2-methylquinolin-6-yl)methyl]piperidin-1-yl}carbonyl)-2-phenylquinoline, Acetyl-CoA carboxylase
Authors:Zhang, H, Tong, L.
Deposit date:2009-04-10
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2.
Bioorg.Med.Chem.Lett., 20, 2010
4G9I
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BU of 4g9i by Molmil
Crystal structure of T.kodakarensis HypF
Descriptor: Hydrogenase maturation protein HypF, ZINC ION
Authors:Tominaga, T, Watanabe, S, Matsumi, R, Atomi, H, Imanaka, T, Miki, K.
Deposit date:2012-07-24
Release date:2012-10-24
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structure of the [NiFe]-hydrogenase maturation protein HypF from Thermococcus kodakarensis KOD1.
Acta Crystallogr.,Sect.F, 68, 2012
3J7Q
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BU of 3j7q by Molmil
Structure of the idle mammalian ribosome-Sec61 complex
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2019-10-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
2ZNJ
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BU of 2znj by Molmil
Crystal structure of Pyrrolysyl-tRNA synthetase from Desulfitobacterium hafniense
Descriptor: Putative uncharacterized protein
Authors:Nozawa, K, Araiso, Y, Soll, D, Ishitani, R, Nureki, O.
Deposit date:2008-04-25
Release date:2008-12-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality
Nature, 457, 2009
8IYJ
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BU of 8iyj by Molmil
Cryo-EM structure of the 48-nm repeat doublet microtubule from mouse sperm
Descriptor: Cilia and flagella-associated protein 77, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ...
Authors:Zhou, L.N, Gui, M, Wu, J.P.
Deposit date:2023-04-05
Release date:2023-07-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility.
Cell, 186, 2023
1HOO
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BU of 1hoo by Molmil
STRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI AT PH 6.5 AND 25 DEGREES CELSIUS
Descriptor: ADENYLOSUCCINATE SYNTHETASE, AMINOPHOSPHONIC ACID-GUANYLATE ESTER, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Poland, B.W, Hou, Z, Bruns, C, Fromm, H.J, Honzatko, R.B.
Deposit date:1996-04-26
Release date:1997-02-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Refined crystal structures of guanine nucleotide complexes of adenylosuccinate synthetase from Escherichia coli.
J.Biol.Chem., 271, 1996
1GIN
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BU of 1gin by Molmil
CRYSTAL STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH GDP, IMP, HADACIDIN, NO3-, AND MG2+. DATA COLLECTED AT 298K (PH 6.5).
Descriptor: ADENYLOSUCCINATE SYNTHETASE, GUANOSINE-5'-DIPHOSPHATE, HADACIDIN, ...
Authors:Poland, B.W, Fromm, H.J, Honzatko, R.B.
Deposit date:1996-06-18
Release date:1997-02-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of adenylosuccinate synthetase from Escherichia coli complexed with GDP, IMP hadacidin, NO3-, and Mg2+.
J.Mol.Biol., 264, 1996
1JUY
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BU of 1juy by Molmil
REFINED CRYSTAL STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH HYDANTOCIDIN 5'-PHOSPHATE GDP, HPO4(2-), MG2+, AND HADACIDIN
Descriptor: ADENYLOSUCCINATE SYNTHETASE, GUANOSINE-5'-DIPHOSPHATE, HADACIDIN, ...
Authors:Poland, B.W, Lee, S.-F, Subramanian, M.V, Siehl, D.L, Anderson, R.J, Fromm, H.J, Honzatko, R.B.
Deposit date:1996-09-25
Release date:1997-06-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Refined crystal structure of adenylosuccinate synthetase from Escherichia coli complexed with hydantocidin 5'-phosphate, GDP, HPO4(2-), Mg2+, and hadacidin.
Biochemistry, 35, 1996
8J2P
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BU of 8j2p by Molmil
Crystal structure of PML B-box2
Descriptor: Maltose/maltodextrin-binding periplasmic protein,Protein PML, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Zhou, C, Zang, N, Zhang, J.
Deposit date:2023-04-15
Release date:2023-09-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function.
Cancer Discov, 13, 2023
8J25
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BU of 8j25 by Molmil
Crystal structure of PML B-box2 mutant
Descriptor: Maltose/maltodextrin-binding periplasmic protein,Protein PML, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Zhou, C, Zang, N, Zhang, J.
Deposit date:2023-04-14
Release date:2023-09-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function.
Cancer Discov, 13, 2023
5OY4
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BU of 5oy4 by Molmil
GSK3beta complex with N-(6-(3,4-dihydroxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)acetamide
Descriptor: Glycogen synthase kinase-3 beta, Proto-oncogene FRAT1, SULFATE ION, ...
Authors:Bax, B.D, Convery, M.A.
Deposit date:2017-09-07
Release date:2017-11-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:From PIM1 to PI3K delta via GSK3 beta : Target Hopping through the Kinome.
ACS Med Chem Lett, 8, 2017
5NAS
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BU of 5nas by Molmil
Crystal structure of human 14-3-3 zeta in complex with PI4KIIIB peptide
Descriptor: 14-3-3 protein zeta/delta, Phosphatidylinositol 4-kinase beta
Authors:Boura, E, Eisenreichova, A.
Deposit date:2017-02-28
Release date:2017-03-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystal structure of human 14-3-3 zeta in complex with PI4KIIIB peptide
To Be Published
2GCQ
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BU of 2gcq by Molmil
Fully ligated E.Coli Adenylosuccinate Synthetase with GTP, 2'-deoxy-IMP and Hadacidin
Descriptor: 9-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-6-(PHOSPHONOOXY)-9H-PURINE, Adenylosuccinate Synthetase, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Honzatko, R.B, Zhou, Y.
Deposit date:2006-03-14
Release date:2007-04-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cavitation as a mechanism of substrate discrimination by adenylosuccinate synthetases
Biochemistry, 45, 2006

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