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8FCH
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BU of 8fch by Molmil
Apo Structure of (N1G37) Methyltransferase from Mycobacterium avium
Descriptor: tRNA (guanine-N(1)-)-methyltransferase
Authors:Isaacson, B, Brylewski, J, Schlegel, F, Cortes, J, Lavallee, T, Mehta, K, Young, A, Doti, L, Battaile, K.P, Stojanoff, V, Perez, A, Bolen, R.
Deposit date:2022-12-01
Release date:2023-12-13
Method:X-RAY DIFFRACTION (1.956 Å)
Cite:Apo structure of (N1G37) Methyltransferase from Mycobacterium avium.
To Be Published
8OGI
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BU of 8ogi by Molmil
Structure of native human eosinophil peroxidase
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Pfanzagl, V, Obinger, C.
Deposit date:2023-03-20
Release date:2024-01-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.547 Å)
Cite:Posttranslational modification and heme cavity architecture of human eosinophil peroxidase-insights from first crystal structure and biochemical characterization.
J.Biol.Chem., 299, 2023
8PE9
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BU of 8pe9 by Molmil
Complex between DDR1 DS-like domain and PRTH-101 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Liu, J, Chiang, H, Xiong, W, Laurent, V, Griffiths, S.C, Duelfer, J, Deng, H, Sun, X, Yin, Y.W, Li, W, Audoly, L.P, An, Z, Schuerpf, T, Li, R, Zhang, N.
Deposit date:2023-06-13
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.152 Å)
Cite:A highly selective humanized DDR1 mAb reverses immune exclusion by disrupting collagen fiber alignment in breast cancer.
J Immunother Cancer, 11, 2023
8P5R
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BU of 8p5r by Molmil
Crystal structure of full-length, homohexameric 2-oxoglutarate dehydrogenase KGD from Mycobacterium smegmatis in complex with GarA
Descriptor: CALCIUM ION, Glycogen accumulation regulator GarA, MAGNESIUM ION, ...
Authors:Wagner, T, Mechaly, A.M, Alzari, P.M, Bellinzoni, M.
Deposit date:2023-05-24
Release date:2023-08-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (4.562 Å)
Cite:High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase.
Nat Commun, 14, 2023
5P5B
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BU of 5p5b by Molmil
Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 236
Descriptor: endothiapepsin
Authors:Schiebel, J, Heine, A, Klebe, G.
Deposit date:2016-06-28
Release date:2016-08-03
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (1.209 Å)
Cite:High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits.
Structure, 24, 2016
5P63
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BU of 5p63 by Molmil
Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 264
Descriptor: endothiapepsin
Authors:Schiebel, J, Heine, A, Klebe, G.
Deposit date:2016-06-28
Release date:2016-08-03
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (1.199 Å)
Cite:High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits.
Structure, 24, 2016
5P6F
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BU of 5p6f by Molmil
Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 276
Descriptor: endothiapepsin
Authors:Schiebel, J, Heine, A, Klebe, G.
Deposit date:2016-06-28
Release date:2016-08-03
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (1.129 Å)
Cite:High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits.
Structure, 24, 2016
5P6U
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BU of 5p6u by Molmil
Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 291
Descriptor: endothiapepsin
Authors:Schiebel, J, Heine, A, Klebe, G.
Deposit date:2016-06-28
Release date:2016-08-03
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (1.06 Å)
Cite:High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits.
Structure, 24, 2016
3C2V
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BU of 3c2v by Molmil
Crystal structure of the quinolinate phosphoribosyl transferase (BNA6) from Saccharomyces cerevisiae complexed with PRPP and the inhibitor phthalate
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Nicotinate-nucleotide pyrophosphorylase, PHTHALIC ACID
Authors:di Luccio, E, Wilson, D.K.
Deposit date:2008-01-25
Release date:2008-04-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Comprehensive X-ray Structural Studies of the Quinolinate Phosphoribosyl Transferase (BNA6) from Saccharomyces cerevisiae.
Biochemistry, 47, 2008
5P79
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BU of 5p79 by Molmil
Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 306
Descriptor: endothiapepsin
Authors:Schiebel, J, Heine, A, Klebe, G.
Deposit date:2016-06-28
Release date:2016-08-03
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (1.129 Å)
Cite:High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits.
Structure, 24, 2016
5P7O
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BU of 5p7o by Molmil
Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 321
Descriptor: endothiapepsin
Authors:Schiebel, J, Heine, A, Klebe, G.
Deposit date:2016-06-28
Release date:2016-08-03
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (1.482 Å)
Cite:High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits.
Structure, 24, 2016
5P82
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BU of 5p82 by Molmil
Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 335
Descriptor: endothiapepsin
Authors:Schiebel, J, Heine, A, Klebe, G.
Deposit date:2016-06-28
Release date:2016-08-03
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits.
Structure, 24, 2016
5P8H
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BU of 5p8h by Molmil
Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 350
Descriptor: endothiapepsin
Authors:Schiebel, J, Heine, A, Klebe, G.
Deposit date:2016-06-28
Release date:2016-08-03
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits.
Structure, 24, 2016
5P8U
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BU of 5p8u by Molmil
Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 363
Descriptor: endothiapepsin
Authors:Schiebel, J, Heine, A, Klebe, G.
Deposit date:2016-06-28
Release date:2016-08-03
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits.
Structure, 24, 2016
3BOF
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BU of 3bof by Molmil
Cobalamin-dependent methionine synthase (1-566) from Thermotoga maritima complexed with Zn2+ and Homocysteine
Descriptor: 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydrofolate S-homocysteine methyltransferase, POTASSIUM ION, ...
Authors:Koutmos, M, Smith, J.L, Ludwig, M.L.
Deposit date:2007-12-17
Release date:2008-03-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Metal active site elasticity linked to activation of homocysteine in methionine synthases.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BQR
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BU of 3bqr by Molmil
Crystal structure of human death associated protein kinase 3 (DAPK3) in complex with an imidazo-pyridazine ligand
Descriptor: 4-(6-{[(1R)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid, Death-associated protein kinase 3, GLYCEROL, ...
Authors:Filippakopoulos, P, Rellos, P, Fedorov, O, Niesen, F, Pike, A.C.W, Pilka, E.S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2007-12-20
Release date:2008-02-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure of Human Death Associated Protein Kinase 3 (DAPK3) in Complex with an Imidazo-Pyridazine Ligand.
To be Published
3BRN
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BU of 3brn by Molmil
Crystal Structure of AM182 Serotonin Complex
Descriptor: Lipocalin, SEROTONIN
Authors:Mans, B.J, Ribeiro, J.M, Andersen, J.F.
Deposit date:2007-12-21
Release date:2008-04-01
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure, function, and evolution of biogenic amine-binding proteins in soft ticks.
J.Biol.Chem., 283, 2008
3BTR
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BU of 3btr by Molmil
AR-NLS:Importin-alpha complex
Descriptor: Androgen receptor, Importin subunit alpha-2
Authors:Cutress, M.L, Whitaker, H.C, Mills, I.G, Stewart, M, Neal, D.E.
Deposit date:2007-12-30
Release date:2008-12-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the nuclear import of the human androgen receptor
J.Cell.Sci., 121, 2008
3BKK
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BU of 3bkk by Molmil
Tesis ACE co-crystal structure with ketone ACE inhibitor kAF
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
Authors:Watermeyer, J.M, Kroger, W.L, O'Neill, H.G, Sewell, B.T, Sturrock, E.D.
Deposit date:2007-12-07
Release date:2008-06-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Probing the basis of domain-dependent inhibition using novel ketone inhibitors of Angiotensin-converting enzyme
Biochemistry, 47, 2008
5OYS
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BU of 5oys by Molmil
Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 3
Descriptor: endothiapepsin
Authors:Schiebel, J, Heine, A, Klebe, G.
Deposit date:2016-06-28
Release date:2016-08-03
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (1.649 Å)
Cite:High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits.
Structure, 24, 2016
3BLF
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BU of 3blf by Molmil
Crystal structure of the catalytic domain of LiCMS in complexed with pyruvate
Descriptor: Citramalate synthase from Leptospira interrogans, PYRUVIC ACID, ZINC ION
Authors:Zhang, P, Ma, J.
Deposit date:2007-12-11
Release date:2008-11-11
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular basis of the substrate specificity and the catalytic mechanism of citramalate synthase from Leptospira interrogans.
Biochem.J., 415, 2008
5OZ0
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BU of 5oz0 by Molmil
Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 11
Descriptor: endothiapepsin
Authors:Schiebel, J, Heine, A, Klebe, G.
Deposit date:2016-06-28
Release date:2016-08-03
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits.
Structure, 24, 2016
5OYV
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BU of 5oyv by Molmil
Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 6
Descriptor: endothiapepsin
Authors:Schiebel, J, Heine, A, Klebe, G.
Deposit date:2016-06-28
Release date:2016-08-03
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (1.439 Å)
Cite:High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits.
Structure, 24, 2016
5OZD
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BU of 5ozd by Molmil
Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 24
Descriptor: endothiapepsin
Authors:Schiebel, J, Heine, A, Klebe, G.
Deposit date:2016-06-28
Release date:2016-08-03
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits.
Structure, 24, 2016
3BW8
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BU of 3bw8 by Molmil
Crystal structure of the Clostridium limosum C3 exoenzyme
Descriptor: Mono-ADP-ribosyltransferase C3, SULFATE ION
Authors:Vogelsgesang, M, Stieglitz, B, Herrmann, C, Pautsch, A, Aktories, K.
Deposit date:2008-01-08
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the Clostridium limosum C3 exoenzyme.
Febs Lett., 582, 2008

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