3W4I
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![BU of 3w4i by Molmil](/molmil-images/mine/3w4i) | Crystal Structure of human DAAO in complex with coumpound 8 | Descriptor: | D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, pyridine-2,3-diol | Authors: | Hondo, T, Warizaya, M, Niimi, T, Namatame, I, Yamaguchi, T, Nakanishi, K, Hamajima, T, Harada, K, Sakashita, H, Matsumoto, Y, Orita, M, Watanabe, T, Takeuchi, M. | Deposit date: | 2013-01-09 | Release date: | 2013-05-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | 4-Hydroxypyridazin-3(2H)-one Derivatives as Novel d-Amino Acid Oxidase Inhibitors. J.Med.Chem., 56, 2013
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2IA8
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![BU of 2ia8 by Molmil](/molmil-images/mine/2ia8) | Kinetic and Crystallographic Studies of a Redesigned Manganese-Binding Site in Cytochrome c Peroxidase | Descriptor: | Cytochrome c peroxidase, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Pfister, T, Mirarefi, A.Y, Gengenbach, A.J, Zhao, X, Conaster, C.D.N, Gao, Y.G, Robinson, H, Zukoski, C.F, Wang, A.H.J, Lu, Y. | Deposit date: | 2006-09-07 | Release date: | 2007-08-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Kinetic and crystallographic studies of a redesigned manganese-binding site in cytochrome c peroxidase J.Biol.Inorg.Chem., 12, 2007
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6TLJ
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7LK3
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![BU of 7lk3 by Molmil](/molmil-images/mine/7lk3) | Crystal structure of untwinned human GABARAPL2 | Descriptor: | 1,2-ETHANEDIOL, Gamma-aminobutyric acid receptor-associated protein-like 2 | Authors: | Scicluna, K, Dewson, G, Czabotar, P.E, Birkinshaw, R.W. | Deposit date: | 2021-02-01 | Release date: | 2021-05-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A new crystal form of GABARAPL2. Acta Crystallogr.,Sect.F, 77, 2021
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1JTK
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![BU of 1jtk by Molmil](/molmil-images/mine/1jtk) | Crystal structure of cytidine deaminase from Bacillus subtilis in complex with the inhibitor tetrahydrodeoxyuridine | Descriptor: | TETRAHYDRODEOXYURIDINE, ZINC ION, cytidine deaminase | Authors: | Johansson, E, Mejlhede, N, Neuhard, J, Larsen, S. | Deposit date: | 2001-08-21 | Release date: | 2002-04-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Crystal structure of the tetrameric cytidine deaminase from Bacillus subtilis at 2.0 A resolution. Biochemistry, 41, 2002
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6DG8
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![BU of 6dg8 by Molmil](/molmil-images/mine/6dg8) | Full-length 5-HT3A receptor in a serotonin-bound conformation- State 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, SEROTONIN, ... | Authors: | Basak, S, Chakrapani, S. | Deposit date: | 2018-05-17 | Release date: | 2018-11-07 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.89 Å) | Cite: | Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT3Areceptor. Nature, 563, 2018
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3FF9
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![BU of 3ff9 by Molmil](/molmil-images/mine/3ff9) | Structure of NK cell receptor KLRG1 | Descriptor: | Killer cell lectin-like receptor subfamily G member 1 | Authors: | Li, Y, Mariuzza, R.A. | Deposit date: | 2008-12-02 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition. Immunity, 31, 2009
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8FQX
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![BU of 8fqx by Molmil](/molmil-images/mine/8fqx) | Carbonic Anhydrase II in complex with the alkyl ureas 3g | Descriptor: | 4-hydroxy-3-({[(pyridin-4-yl)methyl]carbamoyl}amino)benzene-1-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | Authors: | Combs, J.E, McKenna, R. | Deposit date: | 2023-01-06 | Release date: | 2023-02-01 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.496 Å) | Cite: | New Insights into Conformationally Restricted Carbonic Anhydrase Inhibitors. Molecules, 28, 2023
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8FQZ
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![BU of 8fqz by Molmil](/molmil-images/mine/8fqz) | Carbonic Anhydrase II in complex with the alkyl urea 3j | Descriptor: | 4-hydroxy-3-{[(4-hydroxybutyl)carbamoyl]amino}benzene-1-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | Authors: | Combs, J.C, McKenna, R. | Deposit date: | 2023-01-06 | Release date: | 2023-02-01 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.467 Å) | Cite: | New Insights into Conformationally Restricted Carbonic Anhydrase Inhibitors. Molecules, 28, 2023
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5ZRN
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8FR1
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![BU of 8fr1 by Molmil](/molmil-images/mine/8fr1) | Carbonic Anhydrase IX in complex with the alkyl urea compound 3g | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-hydroxy-3-({[(pyridin-4-yl)methyl]carbamoyl}amino)benzene-1-sulfonamide, Carbonic anhydrase 2, ... | Authors: | Combs, J.C, McKenna, R. | Deposit date: | 2023-01-06 | Release date: | 2023-02-01 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | New Insights into Conformationally Restricted Carbonic Anhydrase Inhibitors. Molecules, 28, 2023
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8FQY
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![BU of 8fqy by Molmil](/molmil-images/mine/8fqy) | Carbonic Anhydrase II in complex with the alkyl urea 3h | Descriptor: | 4-hydroxy-3-({[2-(pyridin-2-yl)ethyl]carbamoyl}amino)benzene-1-sulfonamide, Carbonic anhydrase 2, ZINC ION | Authors: | Combs, J.C, McKenna, R. | Deposit date: | 2023-01-06 | Release date: | 2023-02-01 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.466 Å) | Cite: | New Insights into Conformationally Restricted Carbonic Anhydrase Inhibitors. Molecules, 28, 2023
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8FR2
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8FR4
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6DG7
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![BU of 6dg7 by Molmil](/molmil-images/mine/6dg7) | Full-length 5-HT3A receptor in a serotonin-bound conformation- State 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, SEROTONIN, ... | Authors: | Basak, S, Chakrapani, S. | Deposit date: | 2018-05-17 | Release date: | 2018-11-07 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT3Areceptor. Nature, 563, 2018
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4QH5
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![BU of 4qh5 by Molmil](/molmil-images/mine/4qh5) | The GLIC pentameric Ligand-Gated Ion Channel (wild-type) crystallized in phosphate buffer | Descriptor: | CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | Authors: | Fourati, Z, Delarue, M, Sauguet, L. | Deposit date: | 2014-05-26 | Release date: | 2015-03-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural characterization of potential modulation sites in the extracellular domain of the prokaryotic pentameric proton-gated ion channel GLIC Acta Crystallogr.,Sect.D, 2015
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2W6Q
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![BU of 2w6q by Molmil](/molmil-images/mine/2w6q) | Crystal structure of Biotin carboxylase from E. coli in complex with the triazine-2,4-diamine fragment | Descriptor: | 6-(2-phenoxyethoxy)-1,3,5-triazine-2,4-diamine, BIOTIN CARBOXYLASE, CHLORIDE ION | Authors: | Mochalkin, I, Miller, J.R. | Deposit date: | 2008-12-18 | Release date: | 2009-05-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
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2W71
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1ZKC
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![BU of 1zkc by Molmil](/molmil-images/mine/1zkc) | Crystal Structure of the cyclophiln_RING domain of human peptidylprolyl isomerase (cyclophilin)-like 2 isoform b | Descriptor: | BETA-MERCAPTOETHANOL, Peptidyl-prolyl cis-trans isomerase like 2 | Authors: | Walker, J.R, Davis, T, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2005-05-02 | Release date: | 2005-08-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases. PLoS Biol., 8, 2010
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1Y4T
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![BU of 1y4t by Molmil](/molmil-images/mine/1y4t) | Ferric binding protein from Campylobacter jejuni | Descriptor: | FE (III) ION, putative iron-uptake ABC transport system periplasmic iron-binding protein | Authors: | Tom-Yew, S.A.L, Cui, D.T, Bekker, E.G, Murphy, M.E.P. | Deposit date: | 2004-12-01 | Release date: | 2005-01-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Anion-independent iron coordination by the Campylobacter jejuni ferric binding protein J.Biol.Chem., 280, 2005
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4I7E
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![BU of 4i7e by Molmil](/molmil-images/mine/4i7e) | Crystal Structure of the Bacillus stearothermophilus Phosphofructokinase Mutant D12A in Complex with PEP | Descriptor: | 6-phosphofructokinase, PHOSPHOENOLPYRUVATE | Authors: | Mosser, R, Reddy, M, Bruning, J.B, Sacchettini, J.C, Reinhart, G.D. | Deposit date: | 2012-11-30 | Release date: | 2013-07-31 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Redefining the Role of the Quaternary Shift in Bacillus stearothermophilus Phosphofructokinase. Biochemistry, 52, 2013
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1MEZ
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![BU of 1mez by Molmil](/molmil-images/mine/1mez) | Structure of the Recombinant Mouse-Muscle Adenylosuccinate Synthetase Complexed with SAMP, GDP, SO4(2-), and Mg(2+) | Descriptor: | 2-[9-(3,4-DIHYDROXY-5-PHOSPHONOOXYMETHYL-TETRAHYDRO-FURAN-2-YL)-9H-PURIN-6-YLAMINO]-SUCCINIC ACID, Adenylosuccinate Synthetase, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Iancu, C.V, Borza, T, Fromm, H.J, Honzatko, R.B. | Deposit date: | 2002-08-09 | Release date: | 2002-10-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Feedback inhibition and product complexes of recombinant mouse muscle adenylosuccinate synthetase. J.Biol.Chem., 277, 2002
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1YBG
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![BU of 1ybg by Molmil](/molmil-images/mine/1ybg) | MurA inhibited by a derivative of 5-sulfonoxy-anthranilic acid | Descriptor: | N-METHYL-N-{2-[(2-NAPHTHYLSULFONYL)AMINO]-5-[(2-NAPHTHYLSULFONYL)OXY]BENZOYL}-L-ASPARTIC ACID, UDP-N-acetylglucosamine 1-carboxyvinyltransferase | Authors: | Eschenburg, S, Priestman, M.A, Abdul-Latif, F.A, Delachaume, C, Fassy, F, Schonbrunn, E. | Deposit date: | 2004-12-20 | Release date: | 2005-02-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A Novel Inhibitor That Suspends the Induced Fit Mechanism of UDP-N-acetylglucosamine Enolpyruvyl Transferase (MurA). J.Biol.Chem., 280, 2005
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4XQM
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1MF1
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![BU of 1mf1 by Molmil](/molmil-images/mine/1mf1) | Structure of the Recombinant Mouse-Muscle Adenylosuccinate Synthetase Complexed with AMP | Descriptor: | ACETATE ION, ADENOSINE MONOPHOSPHATE, Adenylosuccinate Synthetase | Authors: | Iancu, C.V, Borza, T, Fromm, H.J, Honzatko, R.B. | Deposit date: | 2002-08-09 | Release date: | 2002-10-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Feedback inhibition and product complexes of recombinant mouse muscle adenylosuccinate synthetase. J.Biol.Chem., 277, 2002
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