6DG8

Full-length 5-HT3A receptor in a serotonin-bound conformation- State 2

Summary for 6DG8

Entry DOI	10.2210/pdb6dg8/pdb
EMDB information	7882 7883
Descriptor	5-hydroxytryptamine receptor 3A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	membrane protein
Biological source	Mus musculus (Mouse)
Total number of polymer chains	5
Total formula weight	270676.10
Authors	Basak, S.,Chakrapani, S. (deposition date: 2018-05-17, release date: 2018-11-07, Last modification date: 2020-07-29)
Primary citation	Basak, S.,Gicheru, Y.,Rao, S.,Sansom, M.S.P.,Chakrapani, S. Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT3Areceptor. Nature, 563:270-274, 2018 Cited by PubMed: 30401837 DOI: 10.1038/s41586-018-0660-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.89 Å)

Structure validation