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2VDX
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BU of 2vdx by Molmil
Crystal Structure of the reactive loop Cleaved Corticosteroid Binding Globulin
Descriptor: CORTICOSTEROID-BINDING GLOBULIN, SODIUM ION
Authors:Zhou, A, Wei, Z, Read, R.J.
Deposit date:2007-10-13
Release date:2008-05-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release.
J.Mol.Biol., 380, 2008
2WXX
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BU of 2wxx by Molmil
Crystal structure of mouse angiotensinogen in the oxidised form
Descriptor: ANGIOTENSINOGEN
Authors:Zhou, A, Wei, Z, Carrell, R.W, Read, R.J.
Deposit date:2009-11-11
Release date:2010-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
2WY0
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BU of 2wy0 by Molmil
Crystal structure of mouse angiotensinogen in the oxidised form with space group P6122
Descriptor: 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION
Authors:Zhou, A, Wei, Z, Carrell, R.W, Read, R.J.
Deposit date:2009-11-11
Release date:2010-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
2WXZ
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BU of 2wxz by Molmil
Crystal structure of rat angiotensinogen in C2 space group
Descriptor: ANGIOTENSINOGEN
Authors:Zhou, A, Wei, Z, Carrell, R.W, Read, R.J.
Deposit date:2009-11-11
Release date:2010-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
1IMV
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BU of 1imv by Molmil
2.85 A crystal structure of PEDF
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PIGMENT EPITHELIUM-DERIVED FACTOR
Authors:Simonovic, M, Gettins, P.G.W, Volz, K.
Deposit date:2001-05-11
Release date:2001-09-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor.
Proc.Natl.Acad.Sci.USA, 98, 2001
2VH4
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BU of 2vh4 by Molmil
Structure of a loop C-sheet serpin polymer
Descriptor: TENGPIN
Authors:Zhang, Q, Law, R.H.P, Bottomley, S.P, Whisstock, J.C, Buckle, A.M.
Deposit date:2007-11-19
Release date:2008-01-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A Structural Basis for Loop C-Sheet Polymerization in Serpins.
J.Mol.Biol., 376, 2008
2WY1
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BU of 2wy1 by Molmil
Crystal structure of rat angiotensinogen in P321 space group
Descriptor: ANGIOTENSINOGEN
Authors:Zhou, A, Wei, Z, Carrell, R.W, Read, R.J.
Deposit date:2009-11-11
Release date:2010-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
2WXW
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BU of 2wxw by Molmil
Crystal structure of human angiotensinogen
Descriptor: ANGIOTENSINOGEN
Authors:Zhou, A, Wei, Z, Carrell, R.W, Read, R.J.
Deposit date:2009-11-11
Release date:2010-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
1KCT
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BU of 1kct by Molmil
ALPHA1-ANTITRYPSIN
Descriptor: ALPHA1-ANTITRYPSIN
Authors:Song, H.K, Suh, S.W.
Deposit date:1996-08-06
Release date:1997-01-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.46 Å)
Cite:Crystal structure of an uncleaved alpha 1-antitrypsin reveals the conformation of its inhibitory reactive loop.
FEBS Lett., 377, 1995
2WXY
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BU of 2wxy by Molmil
Crystal structure of mouse angiotensinogen in the reduced form
Descriptor: 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION
Authors:Zhou, A, Wei, Z, Carrell, R.W, Read, R.J.
Deposit date:2009-11-11
Release date:2010-10-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
1LQ8
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BU of 1lq8 by Molmil
Crystal structure of cleaved protein C inhibitor
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Huntington, J.A, Kjellberg, M, Stenflo, J.
Deposit date:2002-05-09
Release date:2003-02-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Protein C Inhibitor Provides Insights into Hormone Binding and Heparin Activation
Structure, 11, 2003
1IZ2
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BU of 1iz2 by Molmil
Interactions causing the kinetic trap in serpin protein folding
Descriptor: alpha-D-glucopyranose-(1-2)-(5R)-5-[(2R)-2-hydroxynonyl]-beta-D-xylulofuranose, alpha1-antitrypsin
Authors:Im, H, Woo, M.-S, Hwang, K.Y, Yu, M.-H.
Deposit date:2002-09-19
Release date:2003-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Interactions causing the kinetic trap in serpin protein folding
J.BIOL.CHEM., 277, 2002
1LK6
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BU of 1lk6 by Molmil
Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous tripeptide
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Zhou, A, Huntington, J.A, Lomas, D.A, Carrell, R.W, Stein, P.E.
Deposit date:2002-04-24
Release date:2003-06-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Serpin Polymerization Is Prevented by a Hydrogen Bond Network That Is Centered on His-334 and Stabilized by Glycerol
J.Biol.Chem., 278, 2003
1LJ5
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BU of 1lj5 by Molmil
1.8A Resolution Structure of Latent Plasminogen Activator Inhibitor-1(PAI-1)
Descriptor: ACETIC ACID, DIMETHYL SULFOXIDE, PLASMINOGEN ACTIVATOR INHIBITOR-1
Authors:Stein, P.E, Baek, K.
Deposit date:2002-04-19
Release date:2002-05-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:

6I7U
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BU of 6i7u by Molmil
Alpha-1-antitrypsin (Ala250Met) in the native conformation
Descriptor: Alpha-1-antitrypsin
Authors:Aldobiyan, I, Lomas, D.A, Irving, J.A.
Deposit date:2018-11-19
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural determinants of instability in alpha-1-antitrypsin
To Be Published
6I3I
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BU of 6i3i by Molmil
Crystal structure of reactive center loop (RCL) cleaved angiotensinogen
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensinogen
Authors:Yan, Y, Read, R.J.
Deposit date:2018-11-06
Release date:2018-12-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Structural basis for the specificity of renin-mediated angiotensinogen cleavage.
J. Biol. Chem., 294, 2019
6I8S
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BU of 6i8s by Molmil
Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1
Descriptor: HEAVY CHAIN OF FAB FRAGMENT FROM AN PAI-1 ANTIBODY, LIGHT CHAIN OF FAB FRAGMENT FROM AN PAI-1 ANTIBODY, Plasminogen activator inhibitor 1
Authors:Vousden, K.A, Lundqvist, T, Popovic, B.
Deposit date:2018-11-21
Release date:2019-02-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1.
Sci Rep, 9, 2019
6I4V
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BU of 6i4v by Molmil
Alpha-1-antitrypsin Queen's (K154N) variant
Descriptor: 3-trimethylsilylpropane-1-sulfonic acid, Alpha-1-antitrypsin, GLYCINE
Authors:Aldobiyan, I, Lomas, D.A, Irving, J.A.
Deposit date:2018-11-12
Release date:2019-11-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural determinants of instability in alpha-1-antitrypsin
To Be Published
6HGK
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BU of 6hgk by Molmil
Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with progesterone
Descriptor: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, PROGESTERONE
Authors:Schmidt, K, Muller, Y.A.
Deposit date:2018-08-23
Release date:2019-05-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.855 Å)
Cite:NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HGD
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BU of 6hgd by Molmil
Crystal structure of Alpha1-antichymotrypsin variant NewBG-0: a new binding globulin variant that is devoid of any cortisol-binding capabilities
Descriptor: Alpha-1-antichymotrypsin
Authors:Gardill, B.R, Schmidt, K, Muller, Y.A.
Deposit date:2018-08-23
Release date:2019-05-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HGG
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BU of 6hgg by Molmil
Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with cortisol
Descriptor: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin
Authors:Schmidt, K, Muller, Y.A.
Deposit date:2018-08-23
Release date:2019-05-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.787 Å)
Cite:NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HGM
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BU of 6hgm by Molmil
Crystal structure of Alpha1-antichymotrypsin variant NewBG-III-allo: an allosterically controlled new binding globulin with an unprecedentedly high ligand release efficacy
Descriptor: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, CALCIUM ION, ...
Authors:Schmidt, K, Muller, Y.A.
Deposit date:2018-08-23
Release date:2019-05-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.369 Å)
Cite:NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HGE
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BU of 6hge by Molmil
Crystal structure of Alpha1-antichymotrypsin variant NewBG-I in the uncleaved S-conformation
Descriptor: Alpha-1-antichymotrypsin
Authors:Gardill, B.R, Schmidt, K, Muller, Y.A.
Deposit date:2018-08-23
Release date:2019-05-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HGI
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BU of 6hgi by Molmil
Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with corticosterone
Descriptor: Alpha-1-antichymotrypsin, CORTICOSTERONE
Authors:Schmidt, K, Muller, Y.A.
Deposit date:2018-08-23
Release date:2019-05-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.517 Å)
Cite:NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HGJ
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BU of 6hgj by Molmil
Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with aldosterone
Descriptor: 1,2-ETHANEDIOL, ALDOSTERONE, Alpha-1-antichymotrypsin
Authors:Schmidt, K, Muller, Y.A.
Deposit date:2018-08-23
Release date:2019-05-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.825 Å)
Cite:NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019

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