PDB: 45566 resultsInfo pagesStatus searchChemie searchBIRD

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3RB5	Crystal structure of calcium binding domain CBD12 of CALX1.1 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Na/Ca exchange protein, ... Authors: Wu, M, Zheng, L. Deposit date: 2011-03-28 Release date: 2011-11-02 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural Basis of the Ca(2+) Inhibitory Mechanism of Drosophila Na(+)/Ca(2+) Exchanger CALX and Its Modification by Alternative Splicing. Structure, 19, 2011
5GGW	Crystal structure of Class C beta-lactamase Descriptor: Beta-lactamase, PHOSPHATE ION, SULFATE ION Authors: An, Y.J, Na, J.H, Cha, S.S. Deposit date: 2016-06-16 Release date: 2017-05-03 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.762 Å) Cite: Structural basis for the extended substrate spectrum of AmpC BER and structure-guided discovery of the inhibition activity of citrate against the class C beta-lactamases AmpC BER and CMY-10. Acta Crystallogr D Struct Biol, 72, 2016
2FWU	Second Ca2+ binding domain of the Na,Ca-exchanger (NCX1) Descriptor: CALCIUM ION, Sodium/calcium exchanger 1 Authors: Hilge, M, Vuister, G.W, Aelen, J. Deposit date: 2006-02-03 Release date: 2006-04-18 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Ca(2+) regulation in the na(+)/ca(2+) exchanger involves two markedly different ca(2+) sensors Mol.Cell, 22, 2006
2AEP	An epidemiologically significant epitope of a 1998 influenza virus neuraminidase forms a highly hydrated interface in the NA-antibody complex. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FAB heavy chain, ... Authors: Venkatramani, L, Bochkareva, E, Lee, J.T, Gulati, U, Laver, W.G, Bochkarev, A, Air, G.M. Deposit date: 2005-07-23 Release date: 2005-12-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.1 Å) Cite: An Epidemiologically Significant Epitope of a 1998 Human Influenza Virus Neuraminidase Forms a Highly Hydrated Interface in the NA-Antibody Complex J.Mol.Biol., 356, 2006
1S45	Crystal structure analysis of the DNA quadruplex d(TGGGGT) S1 Descriptor: 5'-D(*TP*GP*GP*GP*GP*T)-3', MAGNESIUM ION, SODIUM ION, ... Authors: Caceres, C, Wright, G, Gouyette, C, Parkinson, G, Subirana, J.A. Deposit date: 2004-01-15 Release date: 2004-02-24 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: A Thymine tetrad in d(TGGGGT) quadruplexes stabilized with Tl+1/Na+1 ions Nucleic Acids Res., 32, 2004
2FIR	Crystal structure of DFPR-VIIa/sTF Descriptor: CALCIUM ION, CHLORIDE ION, Coagulation factor VII Heavy Chain (EC 3.4.21.21), ... Authors: Bajaj, S.P, Schmidt, A.E, Padmanabhan, K, Bajaj, M.S, Prevost, D, Schreuder, H. Deposit date: 2005-12-30 Release date: 2006-07-11 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2 Å) Cite: High Resolution Structures of p-Aminobenzamidine- and Benzamidine-VIIa/Soluble Tissue Factor: Unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+ and Zn2+ sites in factor VIIa J.Biol.Chem., 281, 2006
2FWS	First Ca2+ binding domain of the Na,Ca-exchanger (NCX1) Descriptor: CALCIUM ION, Sodium/calcium exchanger 1 Authors: Hilge, M, Aelen, J, Vuister, G.W. Deposit date: 2006-02-03 Release date: 2006-04-18 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Ca(2+) regulation in the na(+)/ca(2+) exchanger involves two markedly different ca(2+) sensors Mol.Cell, 22, 2006
1U53	Novel X-Ray Structure of Na-ASP-2, a PR-1 protein from the nematode parasite Necator americanus and a vaccine antigen for human hookworm infection Descriptor: secreted protein ASP-2 Authors: Asojo, O.A, Goud, G, Dhar, K, Loukas, A, Zhan, B, Deumic, V, Liu, S, Borgstahl, G.E.O, Hotez, P.J. Deposit date: 2004-07-26 Release date: 2005-02-01 Last modified: 2017-10-11 Method: X-RAY DIFFRACTION (1.56 Å) Cite: X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection. J.Mol.Biol., 346, 2005
1I92	STRUCTURAL BASIS OF THE NHERF PDZ1-CFTR INTERACTION Descriptor: CHLORIDE ION, NA+/H+ EXCHANGE REGULATORY CO-FACTOR Authors: Karthikeyan, S, Leung, T, Ladias, J.A.A. Deposit date: 2001-03-16 Release date: 2001-06-27 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural basis of the Na+/H+ exchanger regulatory factor PDZ1 interaction with the carboxyl-terminal region of the cystic fibrosis transmembrane conductance regulator. J.Biol.Chem., 276, 2001
2DPK	The Crystal Structure of the Primary Ca2+ Sensor of the Na+/Ca2+ Exchanger Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, GUANIDINE, ... Authors: Abramson, J, Sawaya, M. Deposit date: 2006-05-12 Release date: 2006-06-13 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The crystal structure of the primary Ca2+ sensor of the na+/ca2+ exchanger reveals a novel Ca2+ binding motif. J.Biol.Chem., 281, 2006
2AER	Crystal Structure of Benzamidine-Factor VIIa/Soluble Tissue Factor complex. Descriptor: BENZAMIDINE, CALCIUM ION, CHLORIDE ION, ... Authors: Bajaj, S.P, Schmidt, A.E, Padmanabhan, K, Bajaj, M.S, Liesum, A, Dumas, J, Prevost, D, Schreuder, H. Deposit date: 2005-07-23 Release date: 2006-07-04 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.87 Å) Cite: High Resolution Structures of p-Aminobenzamidine- and Benzamidine-VIIa/Soluble Tissue Factor: Unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+ and Zn2+ sites in factor VIIa J.Biol.Chem., 281, 2006
1G9O	FIRST PDZ DOMAIN OF THE HUMAN NA+/H+ EXCHANGER REGULATORY FACTOR Descriptor: NHE-RF Authors: Karthikeyan, S, Leung, T, Birrane, G, Webster, G, Ladias, J.A.A. Deposit date: 2000-11-26 Release date: 2001-05-23 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains. J.Mol.Biol., 308, 2001
1BKS	TRYPTOPHAN SYNTHASE (E.C.4.2.1.20) FROM SALMONELLA TYPHIMURIUM Descriptor: PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE Authors: Hyde, C.C. Deposit date: 1998-07-10 Release date: 1999-03-23 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Exchange of K+ or Cs+ for Na+ induces local and long-range changes in the three-dimensional structure of the tryptophan synthase alpha2beta2 complex. Biochemistry, 35, 1996
6PZG	Crystal structure of human NA-80 Fab Descriptor: NA-80 Fab heavy chain, NA-80 Fab light chain Authors: Zhu, X, Wilson, I.A. Deposit date: 2019-07-31 Release date: 2019-12-04 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies. Cell Host Microbe, 26, 2019
6PZH	Crystal structure of human NA-22 Fab Descriptor: NA-22 Fab heavy chain, NA-22 Fab light chain Authors: Zhu, X, Wilson, I.A. Deposit date: 2019-07-31 Release date: 2019-12-04 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies. Cell Host Microbe, 26, 2019
8QRO	ASCT2 trimer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS) Descriptor: GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION Authors: Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. Deposit date: 2023-10-09 Release date: 2024-08-14 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
8QRV	ASCT2 protomer in lipid nanodiscs under low Na+ concentration in the outward-facing state (OFS) Descriptor: Neutral amino acid transporter B(0), SODIUM ION Authors: Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. Deposit date: 2023-10-09 Release date: 2024-08-14 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
8QRP	ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS.1) Descriptor: GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION Authors: Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. Deposit date: 2023-10-09 Release date: 2024-08-14 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
8QRR	ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS.3) Descriptor: GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION Authors: Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. Deposit date: 2023-10-09 Release date: 2024-08-14 Method: ELECTRON MICROSCOPY (2.78 Å) Cite: Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
8QRW	ASCT2 protomer in lipid nanodiscs under low Na+ concentration in the intermediate outward-facing state (iOFS-up) Descriptor: Neutral amino acid transporter B(0), SODIUM ION Authors: Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. Deposit date: 2023-10-09 Release date: 2024-08-14 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
8QRQ	ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS.2) Descriptor: GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION Authors: Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. Deposit date: 2023-10-09 Release date: 2024-08-14 Method: ELECTRON MICROSCOPY (2.74 Å) Cite: Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
5HXE	Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 100 mM Na+ and zero Ca2+ Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, PENTADECANE, ... Authors: Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D. Deposit date: 2016-01-30 Release date: 2016-05-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.288 Å) Cite: Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger Nat.Struct.Mol.Biol., 23, 2016
5HYA	Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchangerNCX_Mj soaked with 150 mM Na+ and nominal Ca2+ Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ACETATE ION, CALCIUM ION, ... Authors: Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D. Deposit date: 2016-02-01 Release date: 2016-05-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.897 Å) Cite: Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger Nat.Struct.Mol.Biol., 23, 2016
5HXC	Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 20 mM Na+ and zero Ca2+ Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, CALCIUM ION, ... Authors: Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D. Deposit date: 2016-01-30 Release date: 2016-05-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.101 Å) Cite: Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger Nat.Struct.Mol.Biol., 23, 2016
5HWY	Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 10 mM Na+ and zero Ca2+ Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ACETATE ION, PENTADECANE, ... Authors: Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D. Deposit date: 2016-01-29 Release date: 2016-05-18 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.098 Å) Cite: Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger Nat.Struct.Mol.Biol., 23, 2016

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