2FWS

First Ca2+ binding domain of the Na,Ca-exchanger (NCX1)

Summary for 2FWS

• Entry DOI: 10.2210/pdb2fws/pdb
• Related: 2fwu
• NMR Information: BMRB: 7009
• Descriptor: Sodium/calcium exchanger 1, CALCIUM ION (2 entities in total)
• Functional Keywords: beta-sandwich, greek key, cis-proline, beta-bulge, ca2+ binding, metal transport regulator
• Biological source: Canis lupus familiaris (dog)
• Cellular location: Cell membrane; Multi-pass membrane protein: P23685
• Total number of polymer chains: 1
• Total formula weight: 15243.67

Authors

Hilge, M.,Aelen, J.,Vuister, G.W. (deposition date: 2006-02-03, release date: 2006-04-18, Last modification date: 2022-03-09)

• Primary citation: Hilge, M.,Aelen, J.,Vuister, G.W.; Ca(2+) regulation in the na(+)/ca(2+) exchanger involves two markedly different ca(2+) sensors; Mol.Cell, 22:15-25, 2006; PubMed: 16600866; DOI: 10.1016/j.molcel.2006.03.008

Experimental method

SOLUTION NMR