PDB: 195 resultsInfo pagesStatus searchChemie searchBIRD

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8H37	Cryo-EM Structure of the KBTBD2-CUL3-Rbx1-p85a tetrameric complex Descriptor: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ... Authors: Hu, Y, Mao, Q, Chen, Z, Sun, L. Deposit date: 2022-10-08 Release date: 2023-10-11 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (7.52 Å) Cite: Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2. Nat.Struct.Mol.Biol., 31, 2024
8H3F	Cryo-EM Structure of the KBTBD2-CRL3-CSN complex Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... Authors: Hu, Y, Mao, Q, Chen, Z, Sun, L. Deposit date: 2022-10-08 Release date: 2023-10-11 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (6.73 Å) Cite: Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2. Nat.Struct.Mol.Biol., 31, 2024
8H3A	Cryo-EM Structure of the KBTBD2-CRL3~N8(removed)-CSN complex Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... Authors: Hu, Y, Mao, Q, Chen, Z, Sun, L. Deposit date: 2022-10-08 Release date: 2023-10-11 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (7.51 Å) Cite: Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2. Nat.Struct.Mol.Biol., 31, 2024
8H36	Cryo-EM Structure of the KBTBD2-CUL3-Rbx1-p85a dimeric complex Descriptor: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ... Authors: Hu, Y, Mao, Q, Chen, Z, Sun, L. Deposit date: 2022-10-08 Release date: 2023-10-11 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2. Nat.Struct.Mol.Biol., 31, 2024
8H35	Cryo-EM Structure of the KBTBD2-Cul3-Rbx1 octameric complex Descriptor: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ... Authors: Hu, Y, Mao, Q, Chen, Z, Sun, L. Deposit date: 2022-10-08 Release date: 2023-10-11 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (7.41 Å) Cite: Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2. Nat.Struct.Mol.Biol., 31, 2024
8H33	Cryo-EM Structure of the KBTBD2-Cul3-Rbx1 tetrameric complex Descriptor: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ... Authors: Hu, Y, Mao, Q, Chen, Z, Sun, L. Deposit date: 2022-10-07 Release date: 2023-10-11 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (7.86 Å) Cite: Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2. Nat.Struct.Mol.Biol., 31, 2024
8W4J	Cryo-EM structure of the KLHL22 E3 ligase bound to human glutamate dehydrogenase I Descriptor: Glutamate dehydrogenase 1, mitochondrial, Kelch-like protein 22 Authors: Su, M.-Y, Su, M.-Y. Deposit date: 2023-08-24 Release date: 2023-11-01 Last modified: 2023-11-22 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: Cryo-EM structure of the KLHL22 E3 ligase bound to an oligomeric metabolic enzyme. Structure, 31, 2023
8WFG	The Crystal Structure of KEAP1 from Biortus. Descriptor: Kelch-like ECH-associated protein 1 Authors: Wang, F, Cheng, W, Yuan, Z, Qi, J, Shen, Z. Deposit date: 2023-09-19 Release date: 2023-11-22 Method: X-RAY DIFFRACTION (2.251 Å) Cite: The Crystal Structure of KEAP1 from Biortus. To Be Published
8KHP	CULLIN3-KLHL22-RBX1 E3 ligase Descriptor: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch-like protein 22 Authors: Su, M.-Y, Su, M.-Y. Deposit date: 2023-08-22 Release date: 2023-12-13 Method: ELECTRON MICROSCOPY (3.67 Å) Cite: Cryo-EM structure of the KLHL22 E3 ligase bound to an oligomeric metabolic enzyme. Structure, 31, 2023
8K8T	Structure of CUL3-RBX1-KLHL22 complex Descriptor: Cullin-3, Kelch-like protein 22 Authors: Wang, W, Ling, L, Dai, Z, Zuo, P, Yin, Y. Deposit date: 2023-07-31 Release date: 2024-05-22 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: A conserved N-terminal motif of CUL3 contributes to assembly and E3 ligase activity of CRL3 KLHL22. Nat Commun, 15, 2024
8K9I	Structure of CUL3-RBX1-KLHL22 complex without CUL3 NA motif Descriptor: Cullin-3, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... Authors: Wang, W, Ling, L, Dai, Z, Zuo, P, Yin, Y. Deposit date: 2023-08-01 Release date: 2024-05-29 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: A conserved N-terminal motif of CUL3 contributes to assembly and E3 ligase activity of CRL3 KLHL22. Nat Commun, 15, 2024
8P2O	Dimeric mutant S103R of the BTB domain of ZBTB8A from Xenopus laevis Descriptor: 1,2-ETHANEDIOL, Zinc finger and BTB domain-containing protein 8A.1-A Authors: Coste, F, Mance, L, Pukalo, Z, Suskiewicz, M.J. Deposit date: 2023-05-16 Release date: 2024-06-05 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Dimeric mutant S103R of the BTB domain of ZBTB8A from Xenopus laevis To Be Published
8P2P	Polymeric form of the BTB domain of human ZBTB18 Descriptor: Zinc finger and BTB domain-containing protein 18 Authors: Coste, F, Mance, L, Pukalo, Z, Suskiewicz, M.J. Deposit date: 2023-05-16 Release date: 2024-06-05 Method: X-RAY DIFFRACTION (4.15 Å) Cite: Polymeric form of the BTB domain of human ZBTB18 To Be Published
8P2N	Polymeric form of the BTB domain of ZBTB8A from Xenopus laevis Descriptor: Zinc finger and BTB domain-containing protein 8A.1-A Authors: Coste, F, Mance, L, Suskiewicz, M.J. Deposit date: 2023-05-16 Release date: 2024-06-05 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Polymeric form of the BTB domain of ZBTB8A from Xenopus laevis To Be Published
8RIR	S103A mutant of the BTB domain of ZBTB8A from Xenopus laevis Descriptor: Zinc finger and BTB domain-containing protein 8A.1-A Authors: Coste, F, Suskiewicz, M.J. Deposit date: 2023-12-19 Release date: 2024-06-05 Method: X-RAY DIFFRACTION (3.72 Å) Cite: S103A mutant of the BTB domain of ZBTB8A from Xenopus laevis To Be Published
8RIT	Dimeric mutant S103D of the BTB domain of ZBTB8A from Xenopus laevis Descriptor: Zinc finger and BTB domain-containing protein 8A.1-A Authors: Coste, F, Suskiewicz, M.J. Deposit date: 2023-12-19 Release date: 2024-06-05 Method: X-RAY DIFFRACTION (3.75 Å) Cite: Dimeric mutant S103D of the BTB domain of ZBTB8A from Xenopus laevis To Be Published
9B9R	Cryo-EM structure of the ZBTB5 BTB domain filament Descriptor: Zinc finger and BTB domain-containing protein 5 Authors: Park, J, Hunkeler, M, Fischer, E.S. Deposit date: 2024-04-03 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Polymerization of ZBTB transcription factors regulates chromatin occupancy. Mol.Cell, 84, 2024
9B9V	Cryo-EM structure of the ZBTB9 BTB domain filament Descriptor: Zinc finger and BTB domain-containing protein 9 Authors: Park, J, Hunkeler, M, Fischer, E.S. Deposit date: 2024-04-03 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (8.1 Å) Cite: Polymerization of ZBTB transcription factors regulates chromatin occupancy. Mol.Cell, 84, 2024
8RC6	Cryo-EM structure of hexameric BTB domain of Drosophila CG6765 protein Descriptor: BTB domain of CG6765 protein Authors: Bonchuk, A.N, Naschberger, A, Baradaran, R. Deposit date: 2023-12-06 Release date: 2024-09-11 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: The Arthropoda-specific Tramtrack group BTB protein domains use previously unknown interface to form hexamers. Elife, 13, 2024
9DU7	KEAP1 BTB domain in complex with the covalent activator VVD-065 Descriptor: 1-{(3S)-3-[3-(4-amino-1,3,5-triazin-2-yl)-5-chlorophenyl]morpholin-4-yl}propan-1-one, Kelch-like ECH-associated protein 1 Authors: Bernard, S.M. Deposit date: 2024-10-02 Release date: 2024-10-23 Method: X-RAY DIFFRACTION (1.867 Å) Cite: Suppression of NRF2-dependent cancer growth by a covalent allosteric molecular glue Biorxiv, 2024

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