4DTS
| RB69 DNA Polymerase Ternary Complex with dCTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... | Authors: | Xia, S, Wang, J, Konigsberg, W.H. | Deposit date: | 2012-02-21 | Release date: | 2012-06-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
|
|
4DTU
| RB69 DNA Polymerase Ternary Complex with dGTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... | Authors: | Xia, S, Wang, J, Konigsberg, W.H. | Deposit date: | 2012-02-21 | Release date: | 2012-06-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
|
|
4FJL
| RB69 DNA polymerase ternary complex with dGTP/dA | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... | Authors: | Xia, S, Wang, J, Konigsberg, W.H. | Deposit date: | 2012-06-11 | Release date: | 2012-12-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase. J.Am.Chem.Soc., 135, 2013
|
|
8TLT
| Cryo-EM structure of Rev1(deltaN)-Polzeta-DNA-dCTP complex | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*TP*AP*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*GP*AP*AP*T)-3'), ... | Authors: | Malik, R, Aggarwal, A.K. | Deposit date: | 2023-07-27 | Release date: | 2024-05-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Cryo-EM structure of the Rev1-Pol zeta holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis. Nat.Struct.Mol.Biol., 2024
|
|
8TLQ
| Cryo-EM structure of the Rev1-Polzeta-DNA-dCTP complex | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ... | Authors: | Malik, R, Aggarwal, A.K. | Deposit date: | 2023-07-27 | Release date: | 2024-05-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | Cryo-EM structure of the Rev1-Pol zeta holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis. Nat.Struct.Mol.Biol., 2024
|
|
8UCU
| Partial DNA termination subcomplex of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ... | Authors: | Mullins, E.A, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-09-27 | Release date: | 2023-10-11 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8UCW
| Complete DNA termination subcomplex 2 of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ... | Authors: | Mullins, E.A, Chazin, W.C, Eichman, B.F. | Deposit date: | 2023-09-27 | Release date: | 2023-10-11 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8UCV
| Complete DNA termination subcomplex 1 of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ... | Authors: | Mullins, E.A, Chazin, W.C, Eichman, B.F. | Deposit date: | 2023-09-27 | Release date: | 2023-10-11 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.81 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8WPK
| Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with exgenous DNA | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA polymerase, DNA polymerase processivity factor, ... | Authors: | Wang, X, Li, N, Gao, N. | Deposit date: | 2023-10-10 | Release date: | 2023-11-29 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
|
|
8WPE
| Structure of monkeypox virus polymerase complex F8-A22-E4-H5 (tag-free A22) with exogenous DNA | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, A22R DNA polymerase processivity factor, DNA polymerase, ... | Authors: | Wang, X, Li, N, Gao, N. | Deposit date: | 2023-10-10 | Release date: | 2023-11-29 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
|
|
8WPP
| Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with endogenous DNA | Descriptor: | A22R DNA polymerase processivity factor, DNA polymerase, E4R Uracil-DNA glycosylase, ... | Authors: | Wang, X, Li, N, Gao, N. | Deposit date: | 2023-10-10 | Release date: | 2023-11-29 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
|
|
8V6J
| DNA elongation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-12-01 | Release date: | 2023-12-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (11.11 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8V5O
| Tetramer core subcomplex (conformation 3) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... | Authors: | Mullins, E.A, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-11-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (8.99 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8V6I
| DNA elongation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-12-01 | Release date: | 2023-12-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (14.06 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8V5N
| Tetramer core subcomplex (conformation 2) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... | Authors: | Mullins, E.A, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-11-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (8.56 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8V6G
| DNA initiation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-12-01 | Release date: | 2023-12-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (11.16 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8V6H
| DNA initiation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-12-01 | Release date: | 2023-12-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (11.11 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
8WPF
| Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with exogenous DNA bearing one abasic site | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, A22R DNA polymerase processivity factor, DNA polymerase, ... | Authors: | Wang, X, Li, N, Gao, N. | Deposit date: | 2023-10-10 | Release date: | 2023-11-29 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
|
|
8V5M
| Tetramer core subcomplex (conformation 1) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... | Authors: | Mullins, E.A, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-11-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (9.22 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
|
|
9ENP
| HSV-1 DNA polymerase-processivity factor complex in exonuclease state with 1-bp DNA mismatch | Descriptor: | CALCIUM ION, DNA (46-MER), DNA (67-MER), ... | Authors: | Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. | Deposit date: | 2024-03-13 | Release date: | 2024-05-29 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.12 Å) | Cite: | Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 2024
|
|
9ENQ
| HSV-1 DNA polymerase-processivity factor complex in exonuclease state active site with 1-bp DNA mismatch | Descriptor: | CALCIUM ION, DNA (46-MER), DNA (67-MER), ... | Authors: | Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. | Deposit date: | 2024-03-13 | Release date: | 2024-05-29 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.12 Å) | Cite: | Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 2024
|
|
4K8Z
| KOD Polymerase in binary complex with dsDNA | Descriptor: | 1,2-ETHANEDIOL, COBALT HEXAMMINE(III), DNA (5'-D(*AP*AP*AP*TP*TP*CP*GP*CP*AP*GP*TP*TP*CP*GP*CP*G)-3'), ... | Authors: | Bergen, K, Betz, K, Welte, W, Diederichs, K, Marx, A. | Deposit date: | 2013-04-19 | Release date: | 2013-06-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structures of KOD and 9N DNA Polymerases Complexed with Primer Template Duplex Chembiochem, 14, 2013
|
|
4KHN
| Crystal structure of the ternary complex of the D714A mutant of RB69 DNA polymerase | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3'), ... | Authors: | Guja, K.E, Jacewicz, A, Trzemecka, A, Plochocka, D, Yakubovskaya, E, Bebenek, A, Garcia-Diaz, M. | Deposit date: | 2013-04-30 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | A Remote Palm Domain Residue of RB69 DNA Polymerase Is Critical for Enzyme Activity and Influences the Conformation of the Active Site. Plos One, 8, 2013
|
|
4KHW
| |
4M3X
| |