8PF3
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![BU of 8pf3 by Molmil](/molmil-images/mine/8pf3) | Crystal structure of Trypanosoma brucei trypanothione reductase in complex with 1-(3,4-dichlorobenzyl)-4-(((5-((4-fluorophenethyl)carbamoyl)furan-2-yl)methyl)(4-fluorophenyl)carbamoyl)-1-(3-phenylpropyl)piperazin-1-ium | Descriptor: | 4-[(3,4-dichlorophenyl)methyl]-~{N}-(4-fluorophenyl)-~{N}-[[5-[2-(4-fluorophenyl)ethylcarbamoyl]furan-2-yl]methyl]-4-(3-phenylpropyl)-1,4$l^{4}-diazinane-1-carboxamide, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Exertier, C, Ilari, A, Fiorillo, A, Antonelli, L. | Deposit date: | 2023-06-15 | Release date: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis. J.Med.Chem., 67, 2024
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8CNR
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![BU of 8cnr by Molmil](/molmil-images/mine/8cnr) | Hybrid Cluster Protein from the thermophilic methanogen Methanothermococcus thermolithotrophicus as isolated in a reduced state at 1.45-A resolution | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, ... | Authors: | Lemaire, O.N, Wagner, T. | Deposit date: | 2023-02-24 | Release date: | 2023-04-19 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural and biochemical elucidation of class I hybrid cluster protein natively extracted from a marine methanogenic archaeon. Front Microbiol, 14, 2023
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5B7G
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![BU of 5b7g by Molmil](/molmil-images/mine/5b7g) | |
8CNS
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![BU of 8cns by Molmil](/molmil-images/mine/8cns) | The Hybrid Cluster Protein from the thermophilic methanogen Methanothermococcus thermolithotrophicus in a mixed redox state after soaking with hydroxylamine, at 1.36-A resolution. | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ... | Authors: | Lemaire, O.N, Wagner, T. | Deposit date: | 2023-02-24 | Release date: | 2023-04-19 | Last modified: | 2023-06-07 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Structural and biochemical elucidation of class I hybrid cluster protein natively extracted from a marine methanogenic archaeon. Front Microbiol, 14, 2023
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5TDT
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5XC8
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![BU of 5xc8 by Molmil](/molmil-images/mine/5xc8) | Crystal structure of GH45 endoglucanase EG27II at pH5.5, in complex with cellobiose | Descriptor: | Endo-beta-1,4-glucanase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Nomura, T, Mizutani, K, Iwase, H, Takahashi, N, Mikami, B. | Deposit date: | 2017-03-22 | Release date: | 2018-03-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | High-resolution crystal structures of the glycoside hydrolase family 45 endoglucanase EG27II from the snail Ampullaria crossean. Acta Crystallogr D Struct Biol, 75, 2019
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7YX4
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![BU of 7yx4 by Molmil](/molmil-images/mine/7yx4) | Structure of the Mimivirus genomic fibre in its compact 5-start helix form | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Putative glucose-methanol-choline oxidoreductase protein | Authors: | Villalta, A, Schmitt, A, Estrozi, L.F, Quemin, E.R.J, Alempic, J.M, Lartigue, A, Prazak, V, Belmudes, L, Vasishtan, D, Colmant, A.M.G, Honore, F.A, Coute, Y, Grunewald, K, Abergel, C. | Deposit date: | 2022-02-15 | Release date: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | The giant mimivirus 1.2 Mb genome is elegantly organized into a 30 nm diameter helical protein shield. Elife, 11, 2022
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8P41
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![BU of 8p41 by Molmil](/molmil-images/mine/8p41) | Crystal structure of glucocerebrosidase in complex with allosteric activator | Descriptor: | 2-[2-[[3,5-bis(trifluoromethyl)phenyl]methylsulfanyl]ethanoylamino]-5-chloranyl-benzoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Schulze, M.-S. | Deposit date: | 2023-05-18 | Release date: | 2024-03-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Identification of ss-Glucocerebrosidase Activators for Glucosylceramide hydrolysis. Chemmedchem, 19, 2024
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5TEN
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![BU of 5ten by Molmil](/molmil-images/mine/5ten) | Structure of 4-Hydroxy-tetrahydrodipicolinate Reductase from Vibrio vulnificus with 2,5 Furan Dicarboxylic and NADH with Intact Polyhistidine Tag | Descriptor: | 2,5 Furan Dicarboxylic Acid, 4-hydroxy-tetrahydrodipicolinate reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Mank, N, Pote, S, Arnette, K, Klapper, V, Chruszcz, M. | Deposit date: | 2016-09-22 | Release date: | 2017-10-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Comparative structural and mechanistic studies of 4-hydroxy-tetrahydrodipicolinate reductases from Mycobacterium tuberculosis and Vibrio vulnificus. Biochim Biophys Acta Gen Subj, 1865, 2021
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5XDC
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![BU of 5xdc by Molmil](/molmil-images/mine/5xdc) | Crystal structure of Indole-bound TdsC from Paenibacillus sp. A11-2 | Descriptor: | GLYCEROL, INDOLE, SULFATE ION, ... | Authors: | Hino, T, Hamamoto, H, Ohshiro, T, Nagano, S. | Deposit date: | 2017-03-28 | Release date: | 2017-08-09 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.5785 Å) | Cite: | Crystal structures of TdsC, a dibenzothiophene monooxygenase from the thermophile Paenibacillus sp. A11-2, reveal potential for expanding its substrate selectivity. J. Biol. Chem., 292, 2017
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1ILQ
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![BU of 1ilq by Molmil](/molmil-images/mine/1ilq) | |
7YNH
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5XDB
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![BU of 5xdb by Molmil](/molmil-images/mine/5xdb) | Crystal structure of FMN-bound TdsC from Paenibacillus sp. A11-2 | Descriptor: | FLAVIN MONONUCLEOTIDE, GLYCEROL, SULFATE ION, ... | Authors: | Hino, T, Hamamoto, H, Ohshiro, T, Nagano, S. | Deposit date: | 2017-03-28 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.811 Å) | Cite: | Crystal structures of TdsC, a dibenzothiophene monooxygenase from the thermophile Paenibacillus sp. A11-2, reveal potential for expanding its substrate selectivity. J. Biol. Chem., 292, 2017
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5BN7
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![BU of 5bn7 by Molmil](/molmil-images/mine/5bn7) | Crystal structure of maltodextrin glucosidase from E.coli at 3.7 A resolution | Descriptor: | Maltodextrin glucosidase | Authors: | Shukla, P.K, Pastor, A, Singh, A.K, Sharma, S, Singh, T.P, Chaudhuri, T.K. | Deposit date: | 2015-05-25 | Release date: | 2015-08-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Role of N-terminal region of Escherichia coli maltodextrin glucosidase in folding and function of the protein Biochim.Biophys.Acta, 1864, 2016
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5LZY
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![BU of 5lzy by Molmil](/molmil-images/mine/5lzy) | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a polyadenylated mRNA. | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | Deposit date: | 2016-10-02 | Release date: | 2016-11-30 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.99 Å) | Cite: | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
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5B66
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![BU of 5b66 by Molmil](/molmil-images/mine/5b66) | Crystal structure analysis of Photosystem II complex | Descriptor: | (3R)-beta,beta-caroten-3-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... | Authors: | Tanaka, A, Fukushima, Y, Kamiya, N. | Deposit date: | 2016-05-25 | Release date: | 2017-02-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Two Different Structures of the Oxygen-Evolving Complex in the Same Polypeptide Frameworks of Photosystem II J. Am. Chem. Soc., 139, 2017
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8PF4
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![BU of 8pf4 by Molmil](/molmil-images/mine/8pf4) | Crystal structure of Trypanosoma brucei trypanothione reductase in complex with 4-(((5-((4-fluorophenethyl)carbamoyl)furan-2-yl)methyl)(4-fluorophenyl)carbamoyl)-1-methyl-1-(3-phenylpropyl)piperazin-1-ium | Descriptor: | DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Exertier, C, Ilari, A, Fiorillo, A, Antonelli, L. | Deposit date: | 2023-06-15 | Release date: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis. J.Med.Chem., 67, 2024
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7YX3
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![BU of 7yx3 by Molmil](/molmil-images/mine/7yx3) | Structure of the Mimivirus genomic fibre in its compact 6-start helix form | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Putative GMC-type oxidoreductase | Authors: | Villalta, A, Schmitt, A, Estrozi, L.F, Quemin, E.R.J, Alempic, J.M, Lartigue, A, Prazak, V, Belmudes, L, Vasishtan, D, Colmant, A.M.G, Honore, F.A, Coute, Y, Grunewald, K, Abergel, C. | Deposit date: | 2022-02-15 | Release date: | 2022-08-10 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | The giant mimivirus 1.2 Mb genome is elegantly organized into a 30-nm diameter helical protein shield. Elife, 11, 2022
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8P3E
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![BU of 8p3e by Molmil](/molmil-images/mine/8p3e) | Crystal structure of glucocerebrosidase in complex with allosteric activator | Descriptor: | 2-[[3-[(4-chlorophenyl)carbamoyl]phenyl]sulfonylamino]benzoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Schulze, M.-S. | Deposit date: | 2023-05-17 | Release date: | 2024-03-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Identification of ss-Glucocerebrosidase Activators for Glucosylceramide hydrolysis. Chemmedchem, 19, 2024
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5XF1
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![BU of 5xf1 by Molmil](/molmil-images/mine/5xf1) | Structure of the Full-length glucagon class B G protein-coupled receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, H, Qiao, A, Yang, D, Yang, L, Dai, A, de Graaf, C, Reedtz-Runge, S, Dharmarajan, V, Zhang, H, Han, G.W, Grant, T, Sierra, R, Weierstall, U, Nelson, G, Liu, W, Wu, Y, Ma, L, Cai, X, Lin, G, Wu, X, Geng, Z, Dong, Y, Song, G, Griffin, P, Lau, J, Cherezov, V, Yang, H, Hanson, M, Stevens, R, Jiang, H, Wang, M, Zhao, Q, Wu, B. | Deposit date: | 2017-04-06 | Release date: | 2017-05-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Structure of the full-length glucagon class B G-protein-coupled receptor. Nature, 546, 2017
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6UFQ
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![BU of 6ufq by Molmil](/molmil-images/mine/6ufq) | Crystal structure of D678N GoxA bound to glycine | Descriptor: | GLYCINE, Glycine Oxidase GoxA, MAGNESIUM ION | Authors: | Yukl, E.T. | Deposit date: | 2019-09-24 | Release date: | 2019-10-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Kinetic and structural evidence that Asp-678 plays multiple roles in catalysis by the quinoprotein glycine oxidase. J.Biol.Chem., 294, 2019
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8HTY
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![BU of 8hty by Molmil](/molmil-images/mine/8hty) | Candida boidinii Formate Dehydrogenase Crystal Structure at 1.4 Angstrom Resolution | Descriptor: | Formate dehydrogenase, SULFATE ION | Authors: | Gul, M, Yuksel, B, Bulut, H, DeMirci, H. | Deposit date: | 2022-12-22 | Release date: | 2023-01-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural analysis of wild-type and Val120Thr mutant Candida boidinii formate dehydrogenase by X-ray crystallography. Acta Crystallogr D Struct Biol, 79, 2023
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5I82
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![BU of 5i82 by Molmil](/molmil-images/mine/5i82) | First Crystal Structure of E.coli Based Recombinant Diphtheria Toxin Mutant CRM197 | Descriptor: | Diphtheria toxin, GLYCEROL, SULFATE ION | Authors: | Minasov, G, Shuvalova, L, Mishra, R.P.N, Goel, A, Dubrovska, I, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-02-18 | Release date: | 2016-03-02 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural and immunological characterization of E. coli derived recombinant CRM 197 protein used as carrier in conjugate vaccines. Biosci.Rep., 38, 2018
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5XGT
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![BU of 5xgt by Molmil](/molmil-images/mine/5xgt) | |
5LZW
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![BU of 5lzw by Molmil](/molmil-images/mine/5lzw) | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA. | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | Authors: | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | Deposit date: | 2016-10-02 | Release date: | 2016-11-30 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
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