5I82

First Crystal Structure of E.coli Based Recombinant Diphtheria Toxin Mutant CRM197

Summary for 5I82

• Entry DOI: 10.2210/pdb5i82/pdb
• Related: 4AE0 4AE1
• Descriptor: Diphtheria toxin, SULFATE ION, GLYCEROL, ... (4 entities in total)
• Functional Keywords: diphtheria toxin, crm197, csgid, recombinant, structural genomics, center for structural genomics of infectious diseases, transferase
• Biological source: Corynebacterium diphtheriae
• Total number of polymer chains: 4
• Total formula weight: 234313.97

Authors

Minasov, G.,Shuvalova, L.,Mishra, R.P.N.,Goel, A.,Dubrovska, I.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2016-02-18, release date: 2016-03-02, Last modification date: 2023-09-27)

• Primary citation: Mishra, R.P.N.,Yadav, R.S.P.,Jones, C.,Nocadello, S.,Minasov, G.,Shuvalova, L.A.,Anderson, W.F.,Goel, A.; Structural and immunological characterization of E. coli derived recombinant CRM 197 protein used as carrier in conjugate vaccines.; Biosci.Rep., 38:-, 2018; PubMed: 29875175; DOI: 10.1042/BSR20180238

Experimental method

X-RAY DIFFRACTION (2.35 Å)