5I82
First Crystal Structure of E.coli Based Recombinant Diphtheria Toxin Mutant CRM197
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Diphtheria toxin | polymer | 535 | 58483.4 | 4 | UniProt (Q5PY51) Pfam (PF02763) Pfam (PF02764) Pfam (PF01324) UniProt (by SIFTS) (Q6NK15) | Corynebacterium diphtheriae | |
| 2 | E, G, H (B, C, D) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | F (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 351 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 535 (UniProt: Q5PY51)
| PDB | External Database | Details |
|---|---|---|
| Glu 52 | Gly 53 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 233933.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 380.3 | |
| All* | Total formula weight | 234314.0 |
