5I82

First Crystal Structure of E.coli Based Recombinant Diphtheria Toxin Mutant CRM197

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005615	cellular_component	extracellular space
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0035821	biological_process	modulation of process of another organism
A	0042802	molecular_function	identical protein binding
A	0047286	molecular_function	NAD+-diphthamide ADP-ribosyltransferase activity
A	0090729	molecular_function	toxin activity
B	0005615	cellular_component	extracellular space
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0035821	biological_process	modulation of process of another organism
B	0042802	molecular_function	identical protein binding
B	0047286	molecular_function	NAD+-diphthamide ADP-ribosyltransferase activity
B	0090729	molecular_function	toxin activity
C	0005615	cellular_component	extracellular space
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0035821	biological_process	modulation of process of another organism
C	0042802	molecular_function	identical protein binding
C	0047286	molecular_function	NAD+-diphthamide ADP-ribosyltransferase activity
C	0090729	molecular_function	toxin activity
D	0005615	cellular_component	extracellular space
D	0016740	molecular_function	transferase activity
D	0016757	molecular_function	glycosyltransferase activity
D	0035821	biological_process	modulation of process of another organism
D	0042802	molecular_function	identical protein binding
D	0047286	molecular_function	NAD+-diphthamide ADP-ribosyltransferase activity
D	0090729	molecular_function	toxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue SO4 B 601

Chain	Residue
B	MET459
B	ARG460
B	ARG462
B	LYS474

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site_id	AC2
Number of Residues	3
Details	binding site for residue GOL B 602

Chain	Residue
A	ASN98
B	GLU413
B	GLY415

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site_id	AC3
Number of Residues	3
Details	binding site for residue SO4 C 601

Chain	Residue
C	LYS474
C	ARG460
C	ARG462

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site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 D 601

Chain	Residue
D	ARG460
D	ARG462
D	LYS474

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