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3FAA
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BU of 3faa by Molmil
Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor
Descriptor: N-[4-(5-fluoro-6-methylpyridin-2-yl)-5-quinoxalin-6-yl-1H-imidazol-2-yl]acetamide, PHOSPHATE ION, TGF-beta receptor type-1
Authors:Boriack-Sjodin, P.A, Fitch, C.
Deposit date:2008-11-16
Release date:2009-01-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:2-Aminoimidazoles inhibitors of TGF-beta receptor 1.
Bioorg.Med.Chem.Lett., 19, 2009
3RD2
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BU of 3rd2 by Molmil
NIP45 SUMO-like Domain 2
Descriptor: NFATC2-interacting protein
Authors:Perry, J.J.P, Arvai, A.S, Tainer, J.A.
Deposit date:2011-03-31
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:DNA repair and global sumoylation are regulated by distinct Ubc9 noncovalent complexes.
Mol.Cell.Biol., 31, 2011
3FBX
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BU of 3fbx by Molmil
Crystal structure of the lysosomal 66.3 kDa protein from mouse solved by S-SAD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Lakomek, K, Dickmanns, A, Mueller, U, Ficner, R.
Deposit date:2008-11-20
Release date:2009-03-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:De novo sulfur SAD phasing of the lysosomal 66.3 kDa protein from mouse
Acta Crystallogr.,Sect.D, 65, 2009
3RH7
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BU of 3rh7 by Molmil
Crystal structure of a putative oxidoreductase (SMa0793) from Sinorhizobium meliloti 1021 at 3.00 A resolution
Descriptor: FLAVIN MONONUCLEOTIDE, Hypothetical oxidoreductase
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2011-04-11
Release date:2011-06-08
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a Hypothetical oxidoreductase (SMa0793) from SINORHIZOBIUM MELILOTI 1021 at 3.00 A resolution
To be published
3RI3
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BU of 3ri3 by Molmil
Actinorhodin Polyketide Ketoreductase Mutant P94L bound to NADPH and the Inhibitor Emodin
Descriptor: 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ketoacyl reductase
Authors:Javidpour, P, Tsai, S.-C.
Deposit date:2011-04-12
Release date:2011-06-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.292 Å)
Cite:Structural and Biochemical Analyses of Regio- and Stereospecificities Observed in a Type II Polyketide Ketoreductase.
Biochemistry, 50, 2011
3EYP
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BU of 3eyp by Molmil
Crystal structure of putative alpha-L-fucosidase from Bacteroides thetaiotaomicron
Descriptor: GLYCEROL, Putative alpha-L-fucosidase
Authors:Bonanno, J.B, Freeman, J, Bain, K.T, Hu, S, Romero, R, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2008-10-21
Release date:2008-11-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of putative alpha-L-fucosidase from Bacteroides thetaiotaomicron
To be Published
3FEA
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BU of 3fea by Molmil
Crystal Structure of HdmX bound to the p53-peptidomimetic Ac-Phe-Met-Aib-Pmp-6-Cl-Trp-Glu-Ac3c-Leu-NH2 at 1.33A
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Mdm4 protein, p53-peptidomimetic Ac-Phe-Met-Aib-Pmp-6-Cl-Trp-Glu-Ac3c-Leu-NH2
Authors:Kallen, J.
Deposit date:2008-11-28
Release date:2009-01-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes
J.Biol.Chem., 284, 2009
3F03
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BU of 3f03 by Molmil
Crystal structure of Pentaerythritol Tetranitrate Reductase complex with 1-nitrocyclohexene
Descriptor: 1-nitrocyclohexene, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
Authors:Roujeinikova, A.R, Toogood, H.S, Leys, D.
Deposit date:2008-10-24
Release date:2008-12-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Structure-based insight into the asymmetric bioreduction of the C=C double bond of alpha,beta-unsaturated nitroalkenes by pentaerythritol tetranitrate reductase.
To be published
3RJO
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BU of 3rjo by Molmil
Crystal Structure of ERAP1 Peptide Binding Domain
Descriptor: 1,2-ETHANEDIOL, Endoplasmic reticulum aminopeptidase 1
Authors:Guo, H.-C, Lakshminarasimhan, D, Gandhi, A.
Deposit date:2011-04-15
Release date:2011-12-21
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the molecular ruler mechanism of the endoplasmic reticulum aminopeptidase ERAP1.
Sci Rep, 1, 2011
3F1J
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BU of 3f1j by Molmil
Crystal structure of the Borna disease virus matrix protein (BDV-M) reveals RNA binding properties
Descriptor: CYTIDINE-5'-MONOPHOSPHATE, Matrix protein, SULFATE ION
Authors:Neumann, P, Lieber, D, Meyer, S, Dautel, P, Kerth, A, Kraus, I, Garten, W, Stubbs, M.T.
Deposit date:2008-10-28
Release date:2009-02-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of the Borna disease virus matrix protein (BDV-M) reveals ssRNA binding properties
Proc.Natl.Acad.Sci.USA, 106, 2009
3FG7
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BU of 3fg7 by Molmil
The crystal structure of villin domain 6
Descriptor: Villin-1
Authors:Wang, H, Burtnick, L.D, Robinson, R.C.
Deposit date:2008-12-05
Release date:2009-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Helix-straightening as an activation mechanism in the gelsolin superfamily of actin regulatory proteins
J.Biol.Chem., 284, 2009
3F1S
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BU of 3f1s by Molmil
Crystal structure of Protein Z complexed with protein Z-dependent inhibitor
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Zhou, A.
Deposit date:2008-10-28
Release date:2009-06-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of protein Z-dependent inhibitor complex shows how protein Z functions as a cofactor in the membrane inhibition of factor X.
Blood, 2009
3RP6
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BU of 3rp6 by Molmil
Crystal Structure of Klebsiella pneumoniae HpxO complexed with FAD
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, flavoprotein monooxygenase
Authors:Hicks, K.A, O'Leary, S.E, Begley, T.P, Ealick, S.E.
Deposit date:2011-04-26
Release date:2012-05-16
Last modified:2013-02-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae.
Biochemistry, 52, 2013
3FHG
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BU of 3fhg by Molmil
Crystal structure of Sulfolobus solfataricus 8-oxoguanine DNA glycosylase (SsOgg)
Descriptor: GLYCEROL, N-glycosylase/DNA lyase, SULFATE ION
Authors:Faucher, F, Doublie, S.
Deposit date:2008-12-09
Release date:2009-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of two archaeal 8-oxoguanine DNA glycosylases provide structural insight into guanine/8-oxoguanine distinction.
Structure, 17, 2009
3F3U
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BU of 3f3u by Molmil
Kinase domain of cSrc in complex with inhibitor RL37 (Type III)
Descriptor: 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-phenylurea, Proto-oncogene tyrosine-protein kinase Src
Authors:Gruetter, C, Klueter, S, Getlik, M, Rauh, D.
Deposit date:2008-10-31
Release date:2009-03-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A new screening assay for allosteric inhibitors of cSrc
Nat.Chem.Biol., 5, 2009
3F47
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BU of 3f47 by Molmil
The Crystal Structure of [Fe]-Hydrogenase (Hmd) Holoenzyme from Methanocaldococcus jannaschii
Descriptor: 5'-O-[(S)-hydroxy{[2-hydroxy-3,5-dimethyl-6-(2-oxoethyl)pyridin-4-yl]oxy}phosphoryl]guanosine, 5,10-methenyltetrahydromethanopterin hydrogenase, CARBON MONOXIDE, ...
Authors:Hiromoto, T, Pilak, O, Warkentin, E, Thauer, R.K, Shima, S, Ermler, U.
Deposit date:2008-10-31
Release date:2009-02-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The crystal structure of C176A mutated [Fe]-hydrogenase suggests an acyl-iron ligation in the active site iron complex.
Febs Lett., 583, 2009
3RPH
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BU of 3rph by Molmil
Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis co-crystallized with ATP/Mg2+.
Descriptor: ADENOSINE MONOPHOSPHATE, ADP/ATP-dependent NAD(P)H-hydrate dehydratase, MAGNESIUM ION, ...
Authors:Shumilin, I.A, Cymborowski, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
Deposit date:2011-04-26
Release date:2011-07-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Identification of unknown protein function using metabolite cocktail screening.
Structure, 20, 2012
3F3Z
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BU of 3f3z by Molmil
Crystal structure of Cryptosporidium parvum calcium dependent protein kinase cgd7_1840 in presence of indirubin E804
Descriptor: 3-({[(3S)-3,4-dihydroxybutyl]oxy}amino)-1H,2'H-2,3'-biindol-2'-one, Calcium/calmodulin-dependent protein kinase with a kinase domain and 4 calmodulin like EF hands, GLYCEROL
Authors:Wernimont, A.K, Lew, J, Wasney, G, Kozieradzki, I, Cossar, D, Vedadi, M, Bochkarev, A, Arrowsmith, C.H, Sundstrom, M, Weigelt, J, Edwards, A.M, Hui, R, Artz, J.D, Amani, M, Structural Genomics Consortium (SGC)
Deposit date:2008-10-31
Release date:2008-12-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Crystal structure of Cryptosporidium parvum calcium dependent protein kinase cgd7_1840 in presence of indirubin E804
To be Published
3RRN
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BU of 3rrn by Molmil
S. cerevisiae dbp5 l327v bound to gle1 h337r and ip6
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K.
Deposit date:2011-04-29
Release date:2011-05-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.001 Å)
Cite:A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export.
Nature, 472, 2011
3RS7
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BU of 3rs7 by Molmil
H-Ras soaked in 50% isopropanol: 1 of 10 in MSCS set
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Mattos, C, Buhrman, G, Kearney, B.
Deposit date:2011-05-02
Release date:2011-09-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Analysis of Binding Site Hot Spots on the Surface of Ras GTPase.
J.Mol.Biol., 413, 2011
3F5S
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BU of 3f5s by Molmil
CRYSTAL STRUCTURE OF putatitve short chain dehydrogenase from Shigella flexneri 2a str. 301
Descriptor: dehydrogenase
Authors:Malashkevich, V.N, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2008-11-04
Release date:2008-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:CRYSTAL STRUCTURE OF putatitve short chain dehydrogenase from Shigella flexneri 2a str. 301
To be Published
3RQ3
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BU of 3rq3 by Molmil
Structure of T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT) in hexagonal crystal form
Descriptor: CHLORIDE ION, T cell immunoreceptor with Ig and ITIM domains
Authors:Ramagopal, U.A, Rubinstein, R, Guo, H, Samanta, D, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2011-04-27
Release date:2011-06-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT) in hexagonal crystal form
To be published
3F89
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BU of 3f89 by Molmil
NEMO CoZi domain
Descriptor: NF-kappa-B essential modulator
Authors:Rahighi, S, Ikeda, F, Kawasaki, M, Akutsu, M, Suzuki, N, Kato, R, Kensche, T, Uejima, T, Bloor, S, Komander, D, Randow, F, Wakatsuki, S, Dikic, I.
Deposit date:2008-11-11
Release date:2009-03-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009
3RSS
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BU of 3rss by Molmil
Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima soaked with NADP
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Putative uncharacterized protein, ...
Authors:Shumilin, I.A, Cymborowski, M, Lesley, S.A, Minor, W.
Deposit date:2011-05-02
Release date:2011-06-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.953 Å)
Cite:Identification of unknown protein function using metabolite cocktail screening.
Structure, 20, 2012
3RTC
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BU of 3rtc by Molmil
Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima soaked with NAD and ATP.
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Shumilin, I.A, Cymborowski, M, Lesley, S.A, Minor, W.
Deposit date:2011-05-03
Release date:2011-06-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Identification of unknown protein function using metabolite cocktail screening.
Structure, 20, 2012

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