3F1S

Crystal structure of Protein Z complexed with protein Z-dependent inhibitor

Summary for 3F1S

Entry DOI	10.2210/pdb3f1s/pdb
Descriptor	Protein Z-dependent protease inhibitor, Vitamin K-dependent protein Z, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	pz, zpi, complex, serpin, protease inhibitor, protease, glycoprotein, secreted, serine protease inhibitor, blood coagulation, cleavage on pair of basic residues, egf-like domain, gamma-carboxyglutamic acid, hydroxylation, serine protease homolog, hydrolase inhibitor-hydrolase complex, hydrolase inhibitor/hydrolase
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	76582.52
Authors	Zhou, A. (deposition date: 2008-10-28, release date: 2009-06-30, Last modification date: 2023-12-27)
Primary citation	Wei, Z.,Yan, Y.,Carrell, R.W.,Zhou, A. Crystal structure of protein Z-dependent inhibitor complex shows how protein Z functions as a cofactor in the membrane inhibition of factor X. Blood, 2009 Cited by PubMed: 19528533 DOI: 10.1182/blood-2009-04-210021 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation