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8UQE	Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 26-residue linker (RING not modeled in density) Descriptor: E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E Authors: Hu, Q, Botuyan, M.V, Mer, G. Deposit date: 2023-10-23 Release date: 2024-01-17 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (3.562 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8UQA	Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 12-residue linker Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, SODIUM ION, ... Authors: Hu, Q, Botuyan, M.V, Mer, G. Deposit date: 2023-10-23 Release date: 2024-01-17 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.049 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8UQB	Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (crystallization condition 1) Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, ZINC ION Authors: Hu, Q, Botuyan, M.V, Mer, G. Deposit date: 2023-10-23 Release date: 2024-01-17 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.484 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
6SC2	Structure of the dynein-2 complex; IFT-train bound model Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 2 light intermediate chain 1, ... Authors: Toropova, K, Zalyte, R, Mukhopadhyay, A.G, Mladenov, M, Carter, A.P, Roberts, A.J. Deposit date: 2019-07-23 Release date: 2019-09-04 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structure of the dynein-2 complex and its assembly with intraflagellar transport trains. Nat.Struct.Mol.Biol., 26, 2019
8UQ9	Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 4-residue linker Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, GLYCEROL, ... Authors: Hu, Q, Botuyan, M.V, Mer, G. Deposit date: 2023-10-23 Release date: 2024-01-17 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
8SFN	WT CRISPR-Cas12a with a 16bp R-loop and nontarget strand in the RuvC active site. Descriptor: CRISPR-associated endonuclease Cas12a, DNA (30-MER), DNA (31-MER), ... Authors: Strohkendl, I, Taylor, D.W. Deposit date: 2023-04-11 Release date: 2024-07-03 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: WT CRISPR-Cas12a with a 16bp R-loop and nontarget strand in the RuvC active site. To Be Published
8SFO	WT CRISPR-Cas12a with a 20bp R-loop and nontarget strand in the RuvC active site. Descriptor: CRISPR-associated endonuclease Cas12a, DNA (35-MER), DNA (40-MER), ... Authors: Strohkendl, I, Taylor, D.W. Deposit date: 2023-04-11 Release date: 2024-07-03 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: WT CRISPR-Cas12a with a 20bp R-loop and nontarget strand in the RuvC active site. To Be Published
1BGF	STAT-4 N-DOMAIN Descriptor: STAT-4 Authors: Vinkemeier, U, Moarefi, I, Darnell, J.E, Kuriyan, J. Deposit date: 1998-05-28 Release date: 1998-09-16 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Structure of the amino-terminal protein interaction domain of STAT-4. Science, 279, 1998
5OKC	Crystal structure of the Ctf18-1-8 module from Ctf18-RFC Descriptor: 1,2-ETHANEDIOL, Chromosome transmission fidelity protein 18, Chromosome transmission fidelity protein 8, ... Authors: Grabarczyk, D.B, Kisker, C. Deposit date: 2017-07-25 Release date: 2017-12-20 Last modified: 2018-01-10 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural Basis for the Recruitment of Ctf18-RFC to the Replisome. Structure, 26, 2018
3Q3D	Crystal structure of BmrR bound to puromycin Descriptor: BmrR promoter DNA, Multidrug-efflux transporter 1 regulator, PUROMYCIN Authors: Bachas, S, Eginton, C, Gunio, G, Wade, H. Deposit date: 2010-12-21 Release date: 2011-06-15 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc.Natl.Acad.Sci.USA, 108, 2011
3MXI	TREX1 3' Exonuclease D18N Familial Chilblain Lupus Mutant Descriptor: CALCIUM ION, DNA (5'-D(*GP*AP*CP*G)-3'), Three prime repair exonuclease 1 Authors: Bailey, S.L, Hollis, T. Deposit date: 2010-05-07 Release date: 2011-05-18 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.55 Å) Cite: X-ray Crystal Structures of TREX1 3' Exonuclease Autoimmune Disease Mutants To be Published
3MXM	TREX1 3' Exonuclease V201D Aicardi-Goutieres Syndrome Mutant Descriptor: CALCIUM ION, DNA (5'-D(*GP*AP*CP*G)-3'), IODIDE ION, ... Authors: Bailey, S.L, Hollis, T. Deposit date: 2010-05-07 Release date: 2011-05-18 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.75 Å) Cite: X-ray Crystal Structures of TREX1 3' Exonuclease Autoimmune Disease Mutants To be Published
2XIG	The structure of the Helicobacter pylori ferric uptake regulator Fur reveals three functional metal binding sites Descriptor: CITRIC ACID, FERRIC UPTAKE REGULATION PROTEIN, ZINC ION Authors: Dian, C, Vitale, S, Leonard, G.A, Fauquant, F, Muller, C, Bahlawane, C, de Reuse, H, Michaud-Soret, I, Terradot, L. Deposit date: 2010-06-29 Release date: 2011-01-19 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.85 Å) Cite: The Structure of the Helicobacter Pylori Ferric Uptake Regulator Fur Reveals Three Functional Metal Binding Sites. Mol.Microbiol., 79, 2011
7ZN7	Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and rat STAT2 CCD Descriptor: B27a, DNA damage-binding protein 1, Signal transducer and activator of transcription, ... Authors: Lauer, S, Spahn, C.M.T, Schwefel, D. Deposit date: 2022-04-20 Release date: 2022-11-09 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.78 Å) Cite: Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor. Embo J., 42, 2023
7ZNN	Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and full-length rat STAT2 Descriptor: B27a, DNA damage-binding protein 1, Signal transducer and activator of transcription, ... Authors: Lauer, S, Spahn, C.M.T, Schwefel, D. Deposit date: 2022-04-21 Release date: 2022-11-09 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor. Embo J., 42, 2023
6C9T	Transcriptional repressor, CouR Descriptor: CouR Authors: Cogan, D.P, Nair, S.K. Deposit date: 2018-01-28 Release date: 2018-05-30 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Structural basis of transcriptional regulation by CouR, a repressor of coumarate catabolism, inRhodopseudomonas palustris. J. Biol. Chem., 293, 2018
2JEX	Transcription activator structure reveals redox control of a replication initiation reaction Descriptor: REGULATORY PROTEIN E2 Authors: Sanders, C.M, Sizov, D, Seavers, P.R, Ortiz-Lombardia, M, Antson, A.A. Deposit date: 2007-01-24 Release date: 2007-05-15 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Transcription Activator Structure Reveals Redox Control of a Replication Initiation Reaction. Nucleic Acids Res., 35, 2007
3NCT	X-ray crystal structure of the bacterial conjugation factor PsiB, a negative regulator of reca Descriptor: Protein psiB Authors: Petrova, V, Satyshur, K.A, George, N.P, McCaslin, D, Cox, M.M, Keck, J.L. Deposit date: 2010-06-05 Release date: 2010-07-21 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: X-ray crystal structure of the bacterial conjugation factor PsiB, a negative regulator of RecA. J.Biol.Chem., 285, 2010
5CRL	Crystal Structure of the Transcription Activator Tn501 MerR in Complex with Mercury (II) Descriptor: MERCURY (II) ION, Mercuric resistance operon regulatory protein Authors: Wang, D, Gan, J.H, Chen, H. Deposit date: 2015-07-23 Release date: 2016-09-07 Last modified: 2023-04-12 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Analysis of the Hg(II)-Regulatory Protein Tn501 MerR from Pseudomonas aeruginosa. Sci Rep, 6, 2016
2JEU	Transcription activator structure reveals redox control of a replication initiation reaction Descriptor: REGULATORY PROTEIN E2 Authors: Sanders, C.M, Sizov, D, Seavers, P.R, Ortiz-Lombardia, M, Antson, A.A. Deposit date: 2007-01-23 Release date: 2007-05-15 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Transcription Activator Structure Reveals Redox Control of a Replication Initiation Reaction. Nucleic Acids Res., 35, 2007
6C28	Transcriptional repressor, CouR, bound to p-coumaroyl-CoA Descriptor: Transcriptional regulator, MarR family, p-coumaroyl-CoA Authors: Cogan, D.P, Nair, S.K. Deposit date: 2018-01-07 Release date: 2018-05-30 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Structural basis of transcriptional regulation by CouR, a repressor of coumarate catabolism, inRhodopseudomonas palustris. J. Biol. Chem., 293, 2018
3NQU	Crystal structure of partially trypsinized (CENP-A/H4)2 heterotetramer Descriptor: Histone H3-like centromeric protein A, Histone H4, SULFATE ION Authors: Sekulic, N, Black, B.E. Deposit date: 2010-06-29 Release date: 2010-08-25 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The structure of (CENP-A-H4)(2) reveals physical features that mark centromeres. Nature, 467, 2010
7ET5	Crystal structure of Arabidopsis TEM1 AP2 domain Descriptor: AP2/ERF and B3 domain-containing transcription repressor TEM1, SULFATE ION Authors: Hu, H, Du, J. Deposit date: 2021-05-12 Release date: 2021-09-15 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.052 Å) Cite: TEM1 combinatorially binds to FLOWERING LOCUS T and recruits a Polycomb factor to repress the floral transition in Arabidopsis. Proc.Natl.Acad.Sci.USA, 118, 2021
4OAY	BldD CTD-c-di-GMP complex Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein Authors: Schumacher, M.A, Tschowri, N, Buttner, M, Brennan, R.G. Deposit date: 2014-01-06 Release date: 2014-11-19 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development. Cell(Cambridge,Mass.), 158, 2014
3MNN	A Ruthenium Antitumour Agent Forms Specific Histone Protein Adducts in the Nucleosome Core Descriptor: 1,3,5-triaza-7-phosphatricyclo[3.3.1.1~3,7~]decane, 1-methyl-4-(1-methylethyl)benzene, DNA (145-MER), ... Authors: Ong, M.S, Davey, C.A. Deposit date: 2010-04-22 Release date: 2011-04-06 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core Chemistry, 17, 2011

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