6SC2

Structure of the dynein-2 complex; IFT-train bound model

Summary for 6SC2

Entry DOI	10.2210/pdb6sc2/pdb
EMDB information	4303 4917 4918
Descriptor	O6-alkylguanine-DNA alkyltransferase mutant,DYNC2H1 variant protein,O6-alkylguanine-DNA alkyltransferase mutant,Cytoplasmic dynein 2 heavy chain 1,DYNC2H1 variant protein,DYNC2H1 variant protein,DYNC2H1 variant protein, MAGNESIUM ION, WD repeat-containing protein 60, ... (10 entities in total)
Functional Keywords	dynein, cilia, intraflagellar transport, complex, motor protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	14
Total formula weight	1363284.98
Authors	Toropova, K.,Zalyte, R.,Mukhopadhyay, A.G.,Mladenov, M.,Carter, A.P.,Roberts, A.J. (deposition date: 2019-07-23, release date: 2019-09-04, Last modification date: 2019-09-18)
Primary citation	Toropova, K.,Zalyte, R.,Mukhopadhyay, A.G.,Mladenov, M.,Carter, A.P.,Roberts, A.J. Structure of the dynein-2 complex and its assembly with intraflagellar transport trains. Nat.Struct.Mol.Biol., 26:823-829, 2019 Cited by PubMed: 31451806 DOI: 10.1038/s41594-019-0286-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation