3ZIP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zip by Molmil](/molmil-images/mine/3zip) | minor-site specific NLS (A58) | Descriptor: | A58NLS, IMPORTIN SUBUNIT ALPHA-2 | Authors: | Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. | Deposit date: | 2013-01-10 | Release date: | 2013-08-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha Traffic, 14, 2013
|
|
8GAI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gai by Molmil](/molmil-images/mine/8gai) | |
8FZK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fzk by Molmil](/molmil-images/mine/8fzk) | |
4E4V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e4v by Molmil](/molmil-images/mine/4e4v) | The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution. | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Importin subunit alpha-2 | Authors: | Hang, P.C, Miknis, Z.M, Franke, W.A, Umland, T.C, Schultz, L.W. | Deposit date: | 2012-03-13 | Release date: | 2013-05-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5283 Å) | Cite: | The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution. To be Published
|
|
8G8R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g8r by Molmil](/molmil-images/mine/8g8r) | |
2X1G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2x1g by Molmil](/molmil-images/mine/2x1g) | Crystal structure of Importin13 - Mago-Y14 complex | Descriptor: | CADMUS, PROTEIN MAGO NASHI, RNA-BINDING PROTEIN 8A | Authors: | Bono, F, Cook, A.G, Gruenwald, M, Ebert, J, Conti, E. | Deposit date: | 2009-12-23 | Release date: | 2010-02-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Nuclear Import Mechanism of the Ejc Component Mago- Y14 Revealed by Structural Studies of Importin 13. Mol.Cell, 37, 2010
|
|
3WPT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wpt by Molmil](/molmil-images/mine/3wpt) | Crystal structure of closed dimer of human importin-alpha1 (Rch1) | Descriptor: | DI(HYDROXYETHYL)ETHER, Importin subunit alpha-1 | Authors: | Miyatake, H, Sanjoh, A, Matsuda, G, Tatsumi, Y, Dohmae, N, Aida, Y. | Deposit date: | 2014-01-17 | Release date: | 2015-01-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.629 Å) | Cite: | Crystal structure of closed dimer of human importin-alpha1 (Rch1) To be Published
|
|
1UN0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1un0 by Molmil](/molmil-images/mine/1un0) | Crystal Structure of Yeast Karyopherin (Importin) alpha in complex with a Nup2p N-terminal fragment | Descriptor: | IMPORTIN ALPHA SUBUNIT, NUCLEOPORIN NUP2 | Authors: | Matsuura, Y, Lange, A, Harreman, M.T, Corbett, A.H, Stewart, M. | Deposit date: | 2003-09-03 | Release date: | 2003-10-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Basis for Nup2P Function in Cargo Release and Karyopherin Recycling in Nuclear Import Embo J., 22, 2003
|
|
4PVZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pvz by Molmil](/molmil-images/mine/4pvz) | Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh2 | Descriptor: | Importin subunit alpha, Inner nuclear membrane protein HEH2 | Authors: | Lokareddy, R.K, Hapsari, A.R, van Rheenen, M, Bhardwaj, A, Veenhoff, L.M, Cingolani, C. | Deposit date: | 2014-03-18 | Release date: | 2015-08-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2. Structure, 23, 2015
|
|
8SG7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sg7 by Molmil](/molmil-images/mine/8sg7) | |
2JDQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jdq by Molmil](/molmil-images/mine/2jdq) | C-terminal domain of influenza A virus polymerase PB2 subunit in complex with human importin alpha5 | Descriptor: | IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC PROTEIN 2 | Authors: | Tarendeau, F, Guilligay, D, Mas, P, Boulo, S, Baudin, F, Ruigrok, R.W.H, Hart, D.J, Cusack, S. | Deposit date: | 2007-01-11 | Release date: | 2007-02-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure and Nuclear Import Function of the C- Terminal Domain of Influenza Virus Polymerase Pb2 Subunit Nat.Struct.Mol.Biol., 14, 2007
|
|
7UMI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7umi by Molmil](/molmil-images/mine/7umi) | Importin a1 bound to Cp183-CTD | Descriptor: | HBV-NLS, Importin subunit alpha-1 | Authors: | Yang, R, Cingolani, G. | Deposit date: | 2022-04-07 | Release date: | 2023-10-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core. Sci Adv, 10, 2024
|
|
3TPO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tpo by Molmil](/molmil-images/mine/3tpo) | |
3TPM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tpm by Molmil](/molmil-images/mine/3tpm) | |
4XZR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xzr by Molmil](/molmil-images/mine/4xzr) | |
2QNA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qna by Molmil](/molmil-images/mine/2qna) | Crystal structure of human Importin-beta (127-876) in complex with the IBB-domain of Snurportin1 (1-65) | Descriptor: | Importin subunit beta-1, SULFATE ION, Snurportin-1 | Authors: | Wohlwend, D, Strasser, A, Dickmanns, A, Ficner, R. | Deposit date: | 2007-07-18 | Release date: | 2008-04-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Structural basis for RanGTP independent entry of spliceosomal U snRNPs into the nucleus. J.Mol.Biol., 374, 2007
|
|
7JVO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jvo by Molmil](/molmil-images/mine/7jvo) | |
5E6Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e6q by Molmil](/molmil-images/mine/5e6q) | Importin alpha binding to XRCC1 NLS peptide | Descriptor: | CHLORIDE ION, DNA repair protein XRCC1 NLS peptide, GLYCEROL, ... | Authors: | Pedersen, L.C, Kirby, T.W, Gassman, N.R, Smith, C.E, Gabel, S.A, Sobhany, M, Wilson, S.H, London, R.E. | Deposit date: | 2015-10-10 | Release date: | 2015-10-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.305 Å) | Cite: | Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS. Sci Rep, 5, 2015
|
|
5EKG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ekg by Molmil](/molmil-images/mine/5ekg) | |
7VPS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vps by Molmil](/molmil-images/mine/7vps) | |
5FC8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fc8 by Molmil](/molmil-images/mine/5fc8) | Mouse importin alpha: Dengue 3 NS5 C-terminal NLS peptide complex | Descriptor: | Importin subunit alpha-1, Nonstructural protein 5 | Authors: | Smith, K.M, Forwood, J.K. | Deposit date: | 2015-12-15 | Release date: | 2016-05-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. PLoS Pathog., 12, 2016
|
|
5HHG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hhg by Molmil](/molmil-images/mine/5hhg) | Mouse importin alpha: Dengue 2 NS5 C-terminal NLS peptide complex | Descriptor: | Importin subunit alpha-1, RNA-directed RNA polymerase NS5 | Authors: | Smith, K.M, Forwood, J.K. | Deposit date: | 2016-01-11 | Release date: | 2016-05-18 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. PLoS Pathog., 12, 2016
|
|
5W4E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5w4e by Molmil](/molmil-images/mine/5w4e) | Importin binding to Tdt NLS peptide | Descriptor: | GLYCEROL, Importin subunit alpha-1,Importin subunit alpha-1, human DNA repair polymerase Tdt | Authors: | Pedersen, L.C, London, R. | Deposit date: | 2017-06-10 | Release date: | 2018-06-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Variations in nuclear localization strategies among pol X family enzymes. Traffic, 2018
|
|
8FUA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fua by Molmil](/molmil-images/mine/8fua) | Crystal structure of mouse Importin alpha in complex with Hendra virus matrix protein NLS1 | Descriptor: | Importin subunit alpha-1, Matrix protein | Authors: | Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K. | Deposit date: | 2023-01-17 | Release date: | 2023-02-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism. Viruses, 15, 2023
|
|
8FUB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fub by Molmil](/molmil-images/mine/8fub) | Crystal structure of human Importin alpha 3 in complex with Hendra virus matrix protein NLS1 | Descriptor: | Importin subunit alpha-3, Matrix protein | Authors: | Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K. | Deposit date: | 2023-01-17 | Release date: | 2023-02-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism. Viruses, 15, 2023
|
|