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4GUV
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BU of 4guv by Molmil
TetX derivatized with Xenon
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, TetX2 protein, ...
Authors:Volkers, G, Palm, G.J, Panjikar, S, Hinrichs, W.
Deposit date:2012-08-29
Release date:2013-04-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Putative dioxygen-binding sites and recognition of tigecycline and minocycline in the tetracycline-degrading monooxygenase TetX.
Acta Crystallogr.,Sect.D, 69, 2013
4H2R
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BU of 4h2r by Molmil
Structure of MHPCO Y270F mutant, 5-hydroxynicotinic acid complex
Descriptor: 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5-hydroxypyridine-3-carboxylic acid, BETA-MERCAPTOETHANOL, ...
Authors:Kobayashi, J, Yoshida, H, Mikami, B, Hayashi, H, Kamitori, S, Yagi, T.
Deposit date:2012-09-13
Release date:2013-09-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.473 Å)
Cite:Crystal structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid oxygenase
To be Published
4J36
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BU of 4j36 by Molmil
Cocrystal Structure of kynurenine 3-monooxygenase in complex with UPF 648 inhibitor(KMO-394UPF)
Descriptor: (1S,2S)-2-(3,4-dichlorobenzoyl)cyclopropanecarboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
Authors:Amaral, M, Levy, C, Heyes, D.J, Lafite, P, Outeiro, T.F, Giorgini, F, Leys, D, Scrutton, N.S.
Deposit date:2013-02-05
Release date:2013-04-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural basis of kynurenine 3-monooxygenase inhibition.
Nature, 496, 2013
4J34
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BU of 4j34 by Molmil
Crystal Structure of kynurenine 3-monooxygenase - truncated at position 394 plus HIS tag cleaved.
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
Authors:Amaral, M, Levy, C, Heyes, D.J, Lafite, P, Outeiro, T.F, Giorgini, F, Leys, D, Scrutton, N.S.
Deposit date:2013-02-05
Release date:2013-04-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural basis of kynurenine 3-monooxygenase inhibition.
Nature, 496, 2013
4J33
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BU of 4j33 by Molmil
Crystal Structure of kynurenine 3-monooxygenase (KMO-394)
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
Authors:Amaral, M, Levy, C, Heyes, D.J, Lafite, P, Outeiro, T.F, Giorgini, F, Leys, D, Scrutton, N.S.
Deposit date:2013-02-05
Release date:2013-04-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structural basis of kynurenine 3-monooxygenase inhibition.
Nature, 496, 2013
4K22
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BU of 4k22 by Molmil
Structure of the C-terminal truncated form of E.Coli C5-hydroxylase UBII involved in ubiquinone (Q8) biosynthesis
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Pecqueur, L, Lombard, M, Golinelli-pimpaneau, B, Fontecave, M.
Deposit date:2013-04-07
Release date:2013-05-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:ubiI, a New Gene in Escherichia coli Coenzyme Q Biosynthesis, Is Involved in Aerobic C5-hydroxylation.
J.Biol.Chem., 288, 2013
4JY2
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BU of 4jy2 by Molmil
Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, native and unliganded form
Descriptor: 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, BETA-MERCAPTOETHANOL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Kobayashi, J, Yoshida, H, Kamitori, S, Hayashi, H, Mizutani, K, Takahashi, N, Mikami, B, Yagi, T.
Deposit date:2013-03-28
Release date:2014-04-02
Method:X-RAY DIFFRACTION (1.935 Å)
Cite:Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase
To be Published
3IHG
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BU of 3ihg by Molmil
Crystal structure of a ternary complex of aklavinone-11 hydroxylase with FAD and aklavinone
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, RdmE, SULFATE ION, ...
Authors:Lindqvist, Y, Koskiniemi, H, Jansson, A, Sandalova, T, Schneider, G.
Deposit date:2009-07-30
Release date:2009-09-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural basis for substrate recognition and specificity in aklavinone-11-hydroxylase from rhodomycin biosynthesis.
J.Mol.Biol., 393, 2009
5KOW
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BU of 5kow by Molmil
Structure of rifampicin monooxygenase
Descriptor: ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, Pentachlorophenol 4-monooxygenase
Authors:Tanner, J.J, Liu, L.-K.
Deposit date:2016-07-01
Release date:2016-09-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Structure of the Antibiotic Deactivating, N-hydroxylating Rifampicin Monooxygenase.
J.Biol.Chem., 291, 2016
3I3L
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BU of 3i3l by Molmil
Crystal structure of CmlS, a flavin-dependent halogenase
Descriptor: Alkylhalidase CmlS, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Podzelinska, K, Soares, A, Jia, Z, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2009-06-30
Release date:2010-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Chloramphenicol Biosynthesis: The Structure of CmlS, a Flavin-Dependent Halogenase Showing a Covalent Flavin-Aspartate Bond
J.Mol.Biol., 397, 2010
5KOX
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BU of 5kox by Molmil
Structure of rifampicin monooxygenase complexed with rifampicin
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Pentachlorophenol 4-monooxygenase, RIFAMPICIN
Authors:Tanner, J.J, Liu, L.-K.
Deposit date:2016-07-01
Release date:2016-09-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of the Antibiotic Deactivating, N-hydroxylating Rifampicin Monooxygenase.
J.Biol.Chem., 291, 2016
2DKH
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BU of 2dkh by Molmil
Crystal structure of 3-hydroxybenzoate hydroxylase from Comamonas testosteroni, in complex with the substrate
Descriptor: 3-HYDROXYBENZOIC ACID, 3-hydroxybenzoate hydroxylase, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Hiromoto, T, Fujiwara, S, Hosokawa, K, Yamaguchi, H.
Deposit date:2006-04-11
Release date:2006-10-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of 3-hydroxybenzoate hydroxylase from Comamonas testosteroni has a large tunnel for substrate and oxygen access to the active site
J.Mol.Biol., 364, 2006
7VWP
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BU of 7vwp by Molmil
Structure of the flavin-dependent monooxygenase FlsO1 from the biosynthesis of fluostatinsin
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, FlsO1, PHOSPHATE ION, ...
Authors:Zhang, Y, Yang, C, Zhang, L, Zhang, C.
Deposit date:2021-11-11
Release date:2022-09-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Biochemical and structural insights of multifunctional flavin-dependent monooxygenase FlsO1-catalyzed unexpected xanthone formation
Nat Commun, 13, 2022
2DKI
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BU of 2dki by Molmil
Crystal structure of 3-hydroxybenzoate hydroxylase from Comamonas testosteroni, under pressure of xenon gas (12 atm)
Descriptor: 3-HYDROXYBENZOATE HYDROXYLASE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
Authors:Hiromoto, T, Fujiwara, S, Hosokawa, K, Yamaguchi, H.
Deposit date:2006-04-11
Release date:2006-10-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of 3-hydroxybenzoate hydroxylase from Comamonas testosteroni has a large tunnel for substrate and oxygen access to the active site
J.Mol.Biol., 364, 2006
4X4J
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BU of 4x4j by Molmil
Structural and Functional Studies of BexE: Insights into Oxidation During BE-7585A Biosynthesis
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Putative oxygenase, SULFATE ION
Authors:Tsai, S.-C, Jackson, D.R, Patel, A, Barajas, J.F, Rohr, J, Yu, X, Liu, H.-W, Sasaki, E, Calveras, J, Metsa-Ketela, M.
Deposit date:2014-12-02
Release date:2015-12-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural and Functional Studies of BexE: Insights into Oxidation During BE-7585A Biosynthesis
To Be Published
3EPT
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BU of 3ept by Molmil
Structure of the rebeccamycin biosynthetic enzyme RebC with reduced flavin
Descriptor: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, RebC, SODIUM ION
Authors:Ryan, K.S, Drennan, C.L.
Deposit date:2008-09-30
Release date:2008-12-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:The FAD cofactor of RebC shifts to an IN conformation upon flavin reduction
Biochemistry, 47, 2008
4EIP
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BU of 4eip by Molmil
Native and K252c bound RebC-10x
Descriptor: 6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one, FLAVIN-ADENINE DINUCLEOTIDE, Putative FAD-monooxygenase
Authors:Goldman, P.J, Ryan, K.S, Howard-Jones, A.R, Hamill, M.J, Elliott, S.J, Walsh, C.T, Drennan, C.L.
Deposit date:2012-04-05
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.332 Å)
Cite:An Unusual Role for a Mobile Flavin in StaC-like Indolocarbazole Biosynthetic Enzymes.
Chem.Biol., 19, 2012
4EIQ
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BU of 4eiq by Molmil
Chromopyrrolic acid-soaked RebC-10x with bound 7-carboxy-K252c
Descriptor: (5S)-7-oxo-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5-carboxylic acid, Putative FAD-monooxygenase
Authors:Goldman, P.J, Ryan, K.S, Howard-Jones, A.R, Hamill, M.J, Elliott, S.J, Walsh, C.T, Drennan, C.L.
Deposit date:2012-04-05
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:An Unusual Role for a Mobile Flavin in StaC-like Indolocarbazole Biosynthetic Enzymes.
Chem.Biol., 19, 2012
7OUJ
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BU of 7ouj by Molmil
Crystal structure of the flavoprotein monooxygenase RubL from rubromycin biosynthesis
Descriptor: (2S)-hexane-1,2,6-triol, 4-HYDROXYPROLINE, CHLORIDE ION, ...
Authors:Saleem-Batcha, R, Toplak, M, Teufel, R.
Deposit date:2021-06-11
Release date:2021-11-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.573 Å)
Cite:Catalytic Control of Spiroketal Formation in Rubromycin Polyketide Biosynthesis.
Angew.Chem.Int.Ed.Engl., 60, 2021
7OUC
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BU of 7ouc by Molmil
Crystal structure of the flavoprotein monooxygenase GrhO5 from griseorhodin A biosynthesis
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Putative FAD-dependent monooxygenase GrhO5
Authors:Saleem-Batcha, R, Toplak, M, Teufel, R.
Deposit date:2021-06-11
Release date:2021-11-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Catalytic Control of Spiroketal Formation in Rubromycin Polyketide Biosynthesis.
Angew.Chem.Int.Ed.Engl., 60, 2021
7OUD
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BU of 7oud by Molmil
Crystal structure of a ternary complex of the flavoprotein monooxygenase GrhO5 with FAD and collinone
Descriptor: Collinone, FAD-dependent monooxygenase GrhO5, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Saleem-Batcha, R, Toplak, M, Teufel, R.
Deposit date:2021-06-11
Release date:2021-11-03
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Catalytic Control of Spiroketal Formation in Rubromycin Polyketide Biosynthesis.
Angew.Chem.Int.Ed.Engl., 60, 2021
2VOU
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BU of 2vou by Molmil
Structure of 2,6-dihydroxypyridine-3-hydroxylase from Arthrobacter nicotinovorans
Descriptor: 2,6-DIHYDROXYPYRIDINE HYDROXYLASE, ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Treiber, N, Schulz, G.E.
Deposit date:2008-02-21
Release date:2008-05-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of 2,6-Dihydroxypyridine 3-Hydroxylase from a Nicotine-Degrading Pathway.
J.Mol.Biol., 379, 2008
4Z2R
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BU of 4z2r by Molmil
Crystal structure of 2-hydroxybiphenyl 3-monooxygenase from Pseudomonas azelaica
Descriptor: 2-hydroxybiphenyl-3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Kanteev, M, Bregman-Cohen, A, Fishman, A.
Deposit date:2015-03-30
Release date:2015-08-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A crystal structure of 2-hydroxybiphenyl 3-monooxygenase with bound substrate provides insights into the enzymatic mechanism.
Biochim.Biophys.Acta, 1854, 2015
1FOH
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BU of 1foh by Molmil
PHENOL HYDROXYLASE FROM TRICHOSPORON CUTANEUM
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, PHENOL, PHENOL HYDROXYLASE
Authors:Enroth, C, Neujahr, H, Schneider, G, Lindqvist, Y.
Deposit date:1998-03-26
Release date:1998-06-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of phenol hydroxylase in complex with FAD and phenol provides evidence for a concerted conformational change in the enzyme and its cofactor during catalysis.
Structure, 6, 1998
4Z2T
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BU of 4z2t by Molmil
Crystal Structure of 2-hydroxybiphenyl 3-monooxygenase W225Y from Pseudomonas azelaica
Descriptor: 2-hydroxybiphenyl-3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Kanteev, M, Bregman-Cohen, A, Fishman, A.
Deposit date:2015-03-30
Release date:2015-08-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A crystal structure of 2-hydroxybiphenyl 3-monooxygenase with bound substrate provides insights into the enzymatic mechanism.
Biochim.Biophys.Acta, 1854, 2015

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