4J34

Crystal Structure of kynurenine 3-monooxygenase - truncated at position 394 plus HIS tag cleaved.

Summary for 4J34

• Entry DOI: 10.2210/pdb4j34/pdb
• Related: 4J2W 4J31 4J33 4J36
• Descriptor: Kynurenine 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
• Functional Keywords: monooxygenase kynurenine his cleaved, oxidoreductase
• Biological source: Saccharomyces cerevisiae (Baker's yeast)
• Cellular location: Mitochondrion outer membrane: P38169
• Total number of polymer chains: 2
• Total formula weight: 91321.92

Authors

Amaral, M.,Levy, C.,Heyes, D.J.,Lafite, P.,Outeiro, T.F.,Giorgini, F.,Leys, D.,Scrutton, N.S. (deposition date: 2013-02-05, release date: 2013-04-10, Last modification date: 2024-02-28)

• Primary citation: Amaral, M.,Levy, C.,Heyes, D.J.,Lafite, P.,Outeiro, T.F.,Giorgini, F.,Leys, D.,Scrutton, N.S.; Structural basis of kynurenine 3-monooxygenase inhibition.; Nature, 496:382-385, 2013; PubMed: 23575632; DOI: 10.1038/nature12039

Experimental method

X-RAY DIFFRACTION (2.03 Å)