PDB: 657 件ウェブページステータス検索Chemie searchBIRD

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5ELQ	Crystal structure of the SNX27 PDZ domain bound to the C-terminal DGKzeta PDZ binding motif 分子名称: GLU-ASP-GLN-GLU-THR-ALA-VAL, Sorting nexin-27, TETRAETHYLENE GLYCOL 著者 Collins, B.M, Clairfeuille, T. 登録日 2015-11-05 公開日 2016-09-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat.Struct.Mol.Biol., 23, 2016
5EM9	Crystal structure of the SNX27 PDZ domain bound to the phosphorylated C-terminal 5HT4(a)R PDZ binding motif 分子名称: SEP-LEU-GLU-SER-CYS-PHE, Sorting nexin-27 著者 Collins, B.M, Clairfeuille, T. 登録日 2015-11-06 公開日 2016-09-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat.Struct.Mol.Biol., 23, 2016
5EMB	Crystal structure of the SNX27 PDZ domain bound to the C-terminal phosphorylated PTHR PDZ binding motif 分子名称: GLU-GLU-TRP-SEP-THR-VAL-MET, Sorting nexin-27 著者 Collins, B.M, Clairfeuille, T. 登録日 2015-11-06 公開日 2016-09-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (0.85 Å) 主引用文献 A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat.Struct.Mol.Biol., 23, 2016
5EMA	Crystal structure of the SNX27 PDZ domain bound to the phosphorylated C-terminal LRRC3B PDZ binding motif 分子名称: ASP-ASP-ILE-SEP-THR-VAL-VAL, GLYCEROL, Sorting nexin-27 著者 Collins, B.M, Clairfeuille, T. 登録日 2015-11-06 公開日 2016-09-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat.Struct.Mol.Biol., 23, 2016
6KZ1	Complex structure of Whirlin and Myosin XVa 分子名称: Myosin XVa, Whirlin 著者 Lin, L, Wang, M, Shi, Y, Zhu, J, Zhang, R. 登録日 2019-09-22 公開日 2020-09-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.694 Å) 主引用文献 Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex. Cell Rep, 34, 2021
6LCA	Crystal structure of human Dishevelled1 PDZ domain homotrimer 分子名称: SULFATE ION, Segment polarity protein dishevelled homolog DVL-1 著者 Yasukochi, S, Numoto, N, Tenno, N, Tenno, T, Ito, N, Hiroaki, H. 登録日 2019-11-18 公開日 2020-11-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of human Dishevelled1 PDZ domain homotrimer To Be Published
5EYZ	CRYSTAL STRUCTURE OF THE PTPN4 PDZ DOMAIN COMPLEXED WITH THE TAILORED PEPTIDE CYTO8-RETEV 分子名称: CHLORIDE ION, CYTO8-RETEV, Tyrosine-protein phosphatase non-receptor type 4 著者 Maisonneuve, P, Vaney, M.C, Babault, B, Caillet-Saguy, C, Lafon, M, Delepierre, M, Cordier, F, Wolff, N. 登録日 2015-11-26 公開日 2016-06-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma. J.Biol.Chem., 291, 2016
5F67	An exquisitely specific PDZ/target recognition revealed by the structure of INAD PDZ3 in complex with TRP channel tail 分子名称: Inactivation-no-after-potential D protein, TRP C terminal Tail 著者 Ye, F, Shang, Y, Liu, W, Zhang, M. 登録日 2015-12-05 公開日 2016-02-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 An Exquisitely Specific PDZ/Target Recognition Revealed by the Structure of INAD PDZ3 in Complex with TRP Channel Tail Structure, 24, 2016
5EZ0	CRYSTAL STRUCTURE OF THE PTPN4 PDZ DOMAIN COMPLEXED WITH THE PDZ BINDING MOTIF OF THE MITOGEN ACTIVATED PROTEIN KINASE P38GAMMA. 分子名称: Mitogen-activated protein kinase 12, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 4 著者 Maisonneuve, P, Vaney, M.C, Caillet-Saguy, C, Lafon, M, Delepierre, M, Cordier, F, Wolff, N. 登録日 2015-11-26 公開日 2016-06-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma. J.Biol.Chem., 291, 2016
5FB8	Structure of Interleukin-16 bound to the 14.1 antibody 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Anti-IL-16 antibody 14.1 Fab domain Heavy Chain, ... 著者 Hall, G, Cowan, R, Bayliss, R, Carr, M. 登録日 2015-12-14 公開日 2016-06-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Structure of a Potential Therapeutic Antibody Bound to Interleukin-16 (IL-16): MECHANISTIC INSIGHTS AND NEW THERAPEUTIC OPPORTUNITIES. J.Biol.Chem., 291, 2016
6MTU	Crystal structure of human Scribble PDZ1:pMCC complex 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Colorectal mutant cancer protein, ... 著者 Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M. 登録日 2018-10-22 公開日 2019-08-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.141 Å) 主引用文献 Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains. Febs J., 286, 2019
6MTV	Crystal structure of human Scribble PDZ1:MCC complex 分子名称: Colorectal mutant cancer protein, DI(HYDROXYETHYL)ETHER, Protein scribble homolog, ... 著者 Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M. 登録日 2018-10-22 公開日 2019-08-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.597 Å) 主引用文献 Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains. Febs J., 286, 2019
6MYE	Crystal structure of human Scribble PDZ1 domain in complex with internal PDZ binding motif of Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF) 分子名称: FORMIC ACID, Protein scribble homolog, Rho guanine nucleotide exchange factor 26, ... 著者 Sun, Y.J, Hou, T, Gakhar, L, Fuentes, E.J. 登録日 2018-11-01 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility. J.Cell Biol., 218, 2019
6MS1	Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC 分子名称: 1,2-ETHANEDIOL, APC C-terminus peptide, Protein scribble homolog 著者 How, J.Y, Kvansakul, M, Caria, S, Humbert, P.O. 登録日 2018-10-16 公開日 2019-02-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC. FEBS Lett., 593, 2019
7X2E	Structure of USH1C PDZ2 and coiled-coil in complex with CDHR2 C-terminal tail 分子名称: Cadherin-related family member 2, GLYCEROL, Harmonin 著者 Yan, W, Chen, G, Li, J. 登録日 2022-02-25 公開日 2022-07-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of the Harmonin PDZ2 and coiled-coil domains in a complex with CDHR2 tail and its implications. Faseb J., 36, 2022
7WEG	Complex structure of PDZD7 and FCHSD2 分子名称: FCHSD2, PDZ domain-containing protein 7, ZINC ION 著者 Wang, H, Lin, L, Lu, Q. 登録日 2021-12-23 公開日 2022-11-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Deafness-related protein PDZD7 forms complex with the C-terminal tail of FCHSD2. Biochem.J., 479, 2022
7XTY	Crystal Structure of the second PDZ domain from human PTPN13 in complex with APC peptide 分子名称: APC-peptide, Tyrosine-protein phosphatase non-receptor type 13 著者 Jing, L.Q, Sun, X.N, Ma, W.H, Zhou, W.J, Wu, D.L. 登録日 2022-05-18 公開日 2023-05-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Targeting PTPN13 with 11 amino acid peptides of C-terminal APC prevents immune evasion of colorectal cancer to be published
8AH7	Crystal Structure of the third PDZ domain of PSD-95 protein in the space group P212121 at pH 4.0 分子名称: SULFATE ION, cDNA FLJ50577, highly similar to Discs large homolog 4 著者 Camara-Artigas, A, Salinas-Garcia, M.C. 登録日 2022-07-20 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 pH-Driven Polymorphic Behaviour of the Third PDZ Domain of PSD95: The Role of Electrostatic Interactions Crystals, 2023
8AH4	Crystal Structure of the third PDZ domain of PSD-95 protein in the space group P3112 at pH 4.0 分子名称: ACETATE ION, cDNA FLJ50577, highly similar to Discs large homolog 4 著者 Camara-Artigas, A, Salinas Garcia, M.C. 登録日 2022-07-20 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 pH-Driven Polymorphic Behaviour of the Third PDZ Domain of PSD95: The Role of Electrostatic Interactions Crystals, 2023
8AH6	Crystal Structure of the third PDZ domain of PSD-95 protein in the space group P21 at pH 4.0 分子名称: ACETATE ION, cDNA FLJ50577, highly similar to Discs large homolog 4 著者 Camara-Artigas, A, Salinas Garcia, M.C. 登録日 2022-07-20 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 pH-Driven Polymorphic Behaviour of the Third PDZ Domain of PSD95: The Role of Electrostatic Interactions Crystals, 2023
8AH5	Crystal Structure of the third PDZ domain of PSD-95 protein in the space group P212121 at pH 4.6 分子名称: ACETATE ION, cDNA FLJ50577, highly similar to Discs large homolog 4 著者 Camara-Artigas, A, Salinas Garcia, M.C. 登録日 2022-07-20 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 pH-Driven Polymorphic Behaviour of the Third PDZ Domain of PSD95: The Role of Electrostatic Interactions Crystals, 2023
8AH8	Crystal Structure of the third PDZ domain of PSD-95 protein in the space group P3121 at pH 3.7 分子名称: cDNA FLJ50577, highly similar to Discs large homolog 4 著者 Camara-Artigas, A, Salinas Garcia, M.C. 登録日 2022-07-20 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 pH-Driven Polymorphic Behaviour of the Third PDZ Domain of PSD95: The Role of Electrostatic Interactions Crystals, 2023
8AAP	Crystal structure of the PDZ tandem of syntenin in complex with compound SYNTi 分子名称: (2S)-2-[[(2S)-2-(6-bromanyl-3-oxidanylidene-1H-isoindol-2-yl)-3-[4-(5-ethanoyl-2-fluoranyl-phenyl)phenyl]propanoyl]amino]propanoic acid, Syntenin-1 著者 Feracci, M, Barral, K. 登録日 2022-07-01 公開日 2023-04-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.174 Å) 主引用文献 Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein-Protein Interaction: A Semi-Automated "Hit Identification-to-Optimization" Approach. J.Med.Chem., 66, 2023
8AAK	Crystal structure of the PDZ tandem of syntenin in complex with compound 29 分子名称: (2~{S})-2-[[(2~{S})-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)-3-phenyl-propanoyl]amino]propanoic acid, GLYCEROL, Syntenin-1 著者 Feracci, M, Barral, K. 登録日 2022-07-01 公開日 2023-04-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.554 Å) 主引用文献 Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein-Protein Interaction: A Semi-Automated "Hit Identification-to-Optimization" Approach. J.Med.Chem., 66, 2023
8AAI	Crystal structure of the PDZ tandem of syntenin in complex with fragment E5 分子名称: (2~{S})-2-[[(2~{S})-3-methyl-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)butanoyl]amino]propanoic acid, Syntenin-1 著者 Feracci, M, Barral, K. 登録日 2022-07-01 公開日 2023-04-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein-Protein Interaction: A Semi-Automated "Hit Identification-to-Optimization" Approach. J.Med.Chem., 66, 2023

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