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1ZKJ
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BU of 1zkj by Molmil
Structural Basis for the Extended Substrate Spectrum of CMY-10, a Plasmid-Encoded Class C beta-lactamase
Descriptor: ACETIC ACID, ZINC ION, extended-spectrum beta-lactamase
Authors:Cha, S.S, Jung, H.I, An, Y.J, Lee, S.H.
Deposit date:2005-05-03
Release date:2006-04-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for the extended substrate spectrum of CMY-10, a plasmid-encoded class C beta-lactamase.
Mol.Microbiol., 60, 2006
2A3U
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BU of 2a3u by Molmil
Crystal structure of sulbactam bound to E166A variant of SHV-1 beta-lactamase
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, ...
Authors:Padayatti, P.S, Helfand, M.S, Totir, M.A, Carey, M.P, Carey, P.R, Bonomo, R.A, van den Akker, F.
Deposit date:2005-06-27
Release date:2005-08-02
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:High Resolution Crystal Structures of the trans-Enamine Intermediates Formed by Sulbactam and Clavulanic Acid and E166A SHV-1 {beta}-Lactamase.
J.Biol.Chem., 280, 2005
2A49
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BU of 2a49 by Molmil
Crystal structure of clavulanic acid bound to E166A variant of SHV-1 beta-lactamase
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, ...
Authors:Padayatti, P.S, Helfand, M.S, Totir, M.A, Carey, M.P, Carey, P.R, Bonomo, R.A, van den Akker, F.
Deposit date:2005-06-28
Release date:2005-08-02
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:High Resolution Crystal Structures of the trans-Enamine Intermediates Formed by Sulbactam and Clavulanic Acid and E166A SHV-1 {beta}-Lactamase.
J.Biol.Chem., 280, 2005
2B5R
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BU of 2b5r by Molmil
1B Lactamase / B Lactamase Inhibitor
Descriptor: Beta-lactamase TEM, Beta-lactamase inhibitory protein
Authors:Rahat, O, Albeck, S, Meged, R, Dym, O, Screiber, G, Israel Structural Proteomics Center (ISPC)
Deposit date:2005-09-29
Release date:2006-04-11
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Binding Hot Spots in the TEM1-BLIP Interface in Light of its Modular Architecture.
J.Mol.Biol., 102, 2006
2BLM
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BU of 2blm by Molmil
BETA-LACTAMASE OF BACILLUS LICHENIFORMIS 749(SLASH)C AT 2 ANGSTROMS RESOLUTION
Descriptor: BETA-LACTAMASE
Authors:Moews, P.C, Knox, J.R, Dideberg, O.
Deposit date:1990-02-02
Release date:1990-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Beta-lactamase of Bacillus licheniformis 749/C at 2 A resolution.
Proteins, 7, 1990
2BLS
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BU of 2bls by Molmil
AMPC BETA-LACTAMASE FROM ESCHERICHIA COLI
Descriptor: AMPC BETA-LACTAMASE
Authors:Usher, K.C, Wery, J.-P, Blaszczak, L.C, Remington, S.J.
Deposit date:1998-06-03
Release date:1998-08-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of AmpC beta-lactamase from Escherichia coli bound to a transition-state analogue: possible implications for the oxyanion hypothesis and for inhibitor design.
Biochemistry, 37, 1998
2CC1
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BU of 2cc1 by Molmil
Crystal structure of the class A beta-lactamase from Mycobacterium fortuitum
Descriptor: Beta-lactamase
Authors:Sauvage, E, Fonze, E, Charlier, P.
Deposit date:2006-01-11
Release date:2006-01-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Crystal structure of the Mycobacterium fortuitum class A beta-lactamase: structural basis for broad substrate specificity.
Antimicrob. Agents Chemother., 50, 2006
2DCF
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BU of 2dcf by Molmil
Crystal structure of 6-aminohexanoate-dimer hydrolase S112A/G181D/H266N mutant with substrate
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-AMINOHEXANOIC ACID, 6-aminohexanoate-dimer hydrolase, ...
Authors:Ohki, T, Shibata, N, Higuchi, Y, Takeo, M, Negoro, S.
Deposit date:2006-01-06
Release date:2007-01-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Nylon-oligomer degrading enzyme/substrate complex: catalytic mechanism of 6-aminohexanoate-dimer hydrolase
J.Mol.Biol., 370, 2007
2DNS
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BU of 2dns by Molmil
The crystal structure of D-amino acid amidase from Ochrobactrum anthropi SV3 complexed with D-Phenylalanine
Descriptor: BARIUM ION, D-PHENYLALANINE, D-amino acid amidase
Authors:Okazaki, S, Suzuki, A, Komeda, H, Asano, Y, Yamane, T.
Deposit date:2006-04-26
Release date:2006-05-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure and Functional Characterization of a D-Stereospecific Amino Acid Amidase from Ochrobactrum anthropi SV3, a New Member of the Penicillin-recognizing Proteins
J.Mol.Biol., 368, 2007
2DRW
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BU of 2drw by Molmil
The crystal structutre of D-amino acid amidase from Ochrobactrum anthropi SV3
Descriptor: BARIUM ION, D-Amino acid amidase
Authors:Okazaki, S, Suzuki, A, Komeda, H, Asano, Y, Yamane, T.
Deposit date:2006-06-15
Release date:2006-07-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure and Functional Characterization of a D-Stereospecific Amino Acid Amidase from Ochrobactrum anthropi SV3, a New Member of the Penicillin-recognizing Proteins
J.Mol.Biol., 368, 2007
2E8I
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BU of 2e8i by Molmil
Structure of 6-aminohexanoate-dimer hydrolase, D1 mutant
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-aminohexanoate-dimer hydrolase, GLYCEROL, ...
Authors:Shibata, N, Higuchi, Y, Negoro, S.
Deposit date:2007-01-20
Release date:2008-01-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Molecular design of a nylon-6 byproduct-degrading enzyme from a carboxylesterase with a beta-lactamase fold.
Febs J., 276, 2009
2EFU
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BU of 2efu by Molmil
The crystal structure of D-amino acid amidase from Ochrobactrum anthropi SV3 complexed with L-phenylalanine
Descriptor: BARIUM ION, D-Amino acid amidase, PHENYLALANINE
Authors:Okazaki, S, Suzuki, A, Mizushima, T, Komeda, H, Asano, Y, Yamane, T.
Deposit date:2007-02-26
Release date:2007-03-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of D-amino-acid amidase complexed with L-phenylalanine and with L-phenylalanine amide: insight into the D-stereospecificity of D-amino-acid amidase from Ochrobactrum anthropi SV3.
Acta Crystallogr.,Sect.D, 64, 2008
2EFX
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BU of 2efx by Molmil
The crystal structure of D-amino acid amidase from Ochrobactrum anthropi SV3 complexed with L-phenylalanine amide
Descriptor: BARIUM ION, D-amino acid amidase, PHENYLALANINE AMIDE
Authors:Okazaki, S, Suzuki, A, Mizushima, T, Komeda, H, Asano, Y, Yamane, T.
Deposit date:2007-02-26
Release date:2007-03-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of D-amino-acid amidase complexed with L-phenylalanine and with L-phenylalanine amide: insight into the D-stereospecificity of D-amino-acid amidase from Ochrobactrum anthropi SV3.
Acta Crystallogr.,Sect.D, 64, 2008
2FFY
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BU of 2ffy by Molmil
AmpC beta-lactamase N289A mutant in complex with a boronic acid deacylation transition state analog compound SM3
Descriptor: (1R)-1-(2-THIENYLACETYLAMINO)-1-PHENYLMETHYLBORONIC ACID, Beta-lactamase, PHOSPHATE ION, ...
Authors:Chen, Y, Minasov, G, Roth, T.A, Prati, F, Shoichet, B.K.
Deposit date:2005-12-20
Release date:2006-03-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:The deacylation mechanism of AmpC beta-lactamase at ultrahigh resolution
J.Am.Chem.Soc., 128, 2006
2G2U
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BU of 2g2u by Molmil
Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) complex
Descriptor: Beta-lactamase SHV-1, Beta-lactamase inhibitory protein
Authors:Reynolds, K.A, Thomson, J.M, Corbett, K.D, Bethel, C.R, Berger, J.M, Kirsch, J.F, Bonomo, R.A, Handel, T.M.
Deposit date:2006-02-16
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface.
J.Biol.Chem., 281, 2006
2G2W
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BU of 2g2w by Molmil
Crystal Structure of the SHV D104K Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) complex
Descriptor: Beta-lactamase SHV-1, Beta-lactamase inhibitory protein
Authors:Reynolds, K.A, Thomson, J.M, Corbett, K.D, Bethel, C.R, Berger, J.M, Kirsch, J.F, Bonomo, R.A, Handel, T.M.
Deposit date:2006-02-16
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface.
J.Biol.Chem., 281, 2006
2GDN
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BU of 2gdn by Molmil
Crystal structure of the Mycobacterium tuberculosis beta-lactamase
Descriptor: Beta-lactamase
Authors:Wang, F, Cassidy, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2006-03-16
Release date:2006-04-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal Structure and Activity Studies of the Mycobacterium tuberculosis {beta}-Lactamase Reveal Its Critical Role in Resistance to {beta}-Lactam Antibiotics.
Antimicrob.Agents Chemother., 50, 2006
2H0T
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BU of 2h0t by Molmil
Crystal structure of the M69V E166A double mutant of SHV-1 b-lactamase complexed to clavulanic acid
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Broad-spectrum beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, ...
Authors:van den Akker, F, Padayatti, P.S.
Deposit date:2006-05-15
Release date:2007-01-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Effect of the inhibitor-resistant M69V substitution on the structures and populations of trans-enamine beta-lactamase intermediates.
Biochemistry, 45, 2006
2H0Y
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BU of 2h0y by Molmil
Crystal structure of the M69V E166A double mutant of SHV-1 b-lactamase complexed to sulbactam
Descriptor: Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, ETHANESULFONIC ACID, ...
Authors:van den Akker, F, Padayatti, P.S.
Deposit date:2006-05-15
Release date:2007-01-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Effect of the inhibitor-resistant M69V substitution on the structures and populations of trans-enamine beta-lactamase intermediates.
Biochemistry, 45, 2006
2H10
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BU of 2h10 by Molmil
Crystal structure of the M69V E166A double mutant of SHV-1 b-lactamase complexed to tazobactam
Descriptor: Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, TAZOBACTAM INTERMEDIATE
Authors:van den Akker, F, Padayatti, P.S.
Deposit date:2006-05-15
Release date:2007-01-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Effect of the inhibitor-resistant M69V substitution on the structures and populations of trans-enamine beta-lactamase intermediates.
Biochemistry, 45, 2006
2H5S
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BU of 2h5s by Molmil
SA2-13 penam sulfone complexed to wt SHV-1 beta-lactamase
Descriptor: (3R)-4-[(4-CARBOXYBUTANOYL)OXY]-N-[(1E)-3-OXOPROP-1-EN-1-YL]-3-SULFINO-D-VALINE, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, SHV-1 beta-lactamase
Authors:van den Akker, F, Padayatti, P.S.
Deposit date:2006-05-27
Release date:2006-10-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Rational Design of a beta-Lactamase Inhibitor Achieved via Stabilization of the trans-Enamine Intermediate: 1.28 A Crystal Structure of wt SHV-1 Complex with a Penam Sulfone.
J.Am.Chem.Soc., 128, 2006
2HDQ
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BU of 2hdq by Molmil
AmpC beta-lactamase in complex with 2-carboxythiophene
Descriptor: Beta-lactamase, THIOPHENE-2-CARBOXYLIC ACID
Authors:Babaoglu, K, Shoichet, B.K.
Deposit date:2006-06-20
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Deconstructing fragment-based inhibitor discovery
Nat.Chem.Biol., 2, 2006
2HDR
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BU of 2hdr by Molmil
AmpC beta-lactamase in complex with 4-Amino-3-hydroxybenzoic acid
Descriptor: 4-AMINO-3-HYDROXYBENZOIC ACID, Beta-lactamase, PHOSPHATE ION
Authors:Babaoglu, K, Shoichet, B.K.
Deposit date:2006-06-20
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Deconstructing fragment-based inhibitor discovery
Nat.Chem.Biol., 2, 2006
2HDS
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BU of 2hds by Molmil
AmpC beta-lactamase in complex with 4-Methanesulfonylamino benzoic acid
Descriptor: 4-[(METHYLSULFONYL)AMINO]BENZOIC ACID, Beta-lactamase, PHOSPHATE ION, ...
Authors:Babaoglu, K, Shoichet, B.K.
Deposit date:2006-06-20
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Deconstructing fragment-based inhibitor discovery
Nat.Chem.Biol., 2, 2006
2HDU
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BU of 2hdu by Molmil
AmpC beta-lactamase in complex with 2-acetamidothiophene-3-carboxylic acid
Descriptor: 2-(ACETYLAMINO)THIOPHENE-3-CARBOXYLIC ACID, Beta-lactamase, PHOSPHATE ION, ...
Authors:Babaoglu, K, Shoichet, B.K.
Deposit date:2006-06-20
Release date:2006-11-07
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Deconstructing fragment-based inhibitor discovery
Nat.Chem.Biol., 2, 2006

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