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6BAU
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BU of 6bau by Molmil
Crystal Structure of GltPh R397C in complex with L-Cysteine
Descriptor: CYSTEINE, Glutamate transporter homolog, SODIUM ION
Authors:Font, J, Scopelliti, A.J, Vandenberg, R.J, Boudker, O, Ryan, R.M.
Deposit date:2017-10-15
Release date:2018-01-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5.
Nat Commun, 9, 2018
2XYS
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BU of 2xys by Molmil
Crystal structure of Aplysia californica AChBP in complex with strychnine
Descriptor: SOLUBLE ACETYLCHOLINE RECEPTOR, STRYCHNINE
Authors:Brams, M, Pandya, A, Kuzmin, D, van Elk, R, Krijnen, L, Yakel, J.L, Tsetlin, V, Smit, A.B, Ulens, C.
Deposit date:2010-11-19
Release date:2011-03-23
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.909 Å)
Cite:A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and D-Tubocurarine by Different Cys-Loop Receptors.
Plos Biol., 9, 2011
2XYT
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BU of 2xyt by Molmil
Crystal structure of Aplysia californica AChBP in complex with d- tubocurarine
Descriptor: D-TUBOCURARINE, SOLUBLE ACETYLCHOLINE RECEPTOR
Authors:Brams, M, Pandya, A, Kuzmin, D, van Elk, R, Krijnen, L, Yakel, J.L, Tsetlin, V, Smit, A.B, Ulens, C.
Deposit date:2010-11-19
Release date:2011-03-23
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and D-Tubocurarine by Different Cys-Loop Receptors.
Plos Biol., 9, 2011
5VK1
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BU of 5vk1 by Molmil
Crystal structure of human MDM4 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
Descriptor: Lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI, Protein Mdm4
Authors:Tolbert, W.D, Gohain, N, Pazgier, M.
Deposit date:2017-04-20
Release date:2018-04-25
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
Chem Sci, 10, 2019
1EWM
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BU of 1ewm by Molmil
THE CYSTEINE PROTEASE CRUZAIN BOUND TO WRR-112
Descriptor: CRUZAIN, N-[3-CARBOXY-2-HYDROXY-PROPIONYL]-L-HOMOPHENYLALANYL-AMINO-2-METHYLBUTANE
Authors:Brinen, L.S, Gillmor, S.A, Fletterick, R.J.
Deposit date:2000-04-26
Release date:2003-06-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Cruzain bound to WRR-112
To be Published
1EWO
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BU of 1ewo by Molmil
THE CYSTEINE PROTEASE CRUZAIN BOUND TO WRR-204
Descriptor: CRUZAIN, N-[N'-BENZYLOXYCARBONYL-PHENYLALANINYL]-3-AMINO-5-PHENYL-PENTANE-1-SULFONIC ACID PHENYL ESTER
Authors:Brinen, L.S, Gillmor, S.A, Fletterick, R.J.
Deposit date:2000-04-26
Release date:2003-06-10
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Cruzain bound to WRR-204
To be Published
2XMT
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BU of 2xmt by Molmil
Copper chaperone Atx1 from Synechocystis PCC6803 (Cu1 form)
Descriptor: COPPER (I) ION, SSR2857 PROTEIN
Authors:Badarau, A, Firbank, S.J, McCarthy, A.A, Banfield, M.J, Dennison, C.
Deposit date:2010-07-29
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Visualizing the Metal-Binding Versatility of Copper Trafficking Sites .
Biochemistry, 49, 2010
2XMU
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BU of 2xmu by Molmil
Copper chaperone Atx1 from Synechocystis PCC6803 (Cu2 form)
Descriptor: COPPER (I) ION, SSR2857 PROTEIN
Authors:Badarau, A, Firbank, S.J, McCarthy, A.A, Banfield, M.J, Dennison, C.
Deposit date:2010-07-29
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Visualizing the Metal-Binding Versatility of Copper Trafficking Sites .
Biochemistry, 49, 2010
2XMV
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BU of 2xmv by Molmil
Copper chaperone Atx1 from Synechocystis PCC6803 (Cu1, trimeric form, His61Tyr mutant)
Descriptor: COPPER (I) ION, SSR2857 PROTEIN
Authors:Badarau, A, Firbank, S.J, McCarthy, A.A, Banfield, M.J, Dennison, C.
Deposit date:2010-07-29
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Visualizing the Metal-Binding Versatility of Copper Trafficking Sites .
Biochemistry, 49, 2010
2XMW
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BU of 2xmw by Molmil
PacS, N-terminal domain, from Synechocystis PCC6803
Descriptor: CATION-TRANSPORTING ATPASE PACS, COPPER (I) ION
Authors:Badarau, A, Firbank, S.J, McCarthy, A.A, Banfield, M.J, Dennison, C.
Deposit date:2010-07-29
Release date:2010-08-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Visualizing the Metal-Binding Versatility of Copper Trafficking Sites .
Biochemistry, 49, 2010
1AIM
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BU of 1aim by Molmil
CRUZAIN INHIBITED BY BENZOYL-TYROSINE-ALANINE-FLUOROMETHYLKETONE
Descriptor: BENZOYL-TYROSINE-ALANINE-FLUORO-METHYL KETONE, CRUZAIN
Authors:Fletterick, R, Gillmor, S.
Deposit date:1997-04-21
Release date:1997-10-22
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural determinants of specificity in the cysteine protease cruzain.
Protein Sci., 6, 1997
1YVB
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BU of 1yvb by Molmil
the Plasmodium falciparum Cysteine Protease Falcipain-2
Descriptor: Cystatin, GLYCEROL, falcipain 2
Authors:Wang, S.X.
Deposit date:2005-02-15
Release date:2006-03-28
Last modified:2024-12-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for unique mechanisms of folding and hemoglobin binding by a malarial protease.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2AIM
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BU of 2aim by Molmil
CRUZAIN INHIBITED WITH BENZOYL-ARGININE-ALANINE-FLUOROMETHYLKETONE
Descriptor: BENZOYL-ARGININE-ALANINE-FLUORO-METHYL KETONE, CRUZAIN
Authors:Gillmor, S.A, Fletterick, R.J.
Deposit date:1997-04-21
Release date:1997-10-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural determinants of specificity in the cysteine protease cruzain.
Protein Sci., 6, 1997
9D6A
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BU of 9d6a by Molmil
Human excitatory amino acid transporter 3 (EAAT3) with bound L-Cysteine in an intermediate outward facing state
Descriptor: CYSTEINE, Excitatory amino acid transporter 3, MERCURY (II) ION, ...
Authors:Qiu, B, Boudker, O.
Deposit date:2024-08-14
Release date:2025-01-22
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis of the excitatory amino acid transporter 3 substrate recognition.
Biorxiv, 2024
9D69
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BU of 9d69 by Molmil
Human excitatory amino acid transporter 3 (EAAT3) with bound L-Cysteine in an intermediate outward facing state (slight upper position)
Descriptor: CYSTEINE, Excitatory amino acid transporter 3, MERCURY (II) ION, ...
Authors:Qiu, B, Boudker, O.
Deposit date:2024-08-14
Release date:2025-01-22
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Structural basis of the excitatory amino acid transporter 3 substrate recognition.
Biorxiv, 2024
9D68
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BU of 9d68 by Molmil
Human excitatory amino acid transporter 3 (EAAT3) with bound L-Cysteine in an outward facing state
Descriptor: CYSTEINE, Excitatory amino acid transporter 3, SODIUM ION
Authors:Qiu, B, Boudker, O.
Deposit date:2024-08-14
Release date:2025-01-22
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Structural basis of the excitatory amino acid transporter 3 substrate recognition.
Biorxiv, 2024
8VBS
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BU of 8vbs by Molmil
E. coli cysteine desulfurase SufS bound to SufE C51A
Descriptor: Cysteine desulfurase, Cysteine desulfuration protein SufE
Authors:Dunkle, J.A, Frantom, P.A, Gilbert, N.C.
Deposit date:2023-12-12
Release date:2024-10-16
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:The structure of the SufS-SufE complex reveals interactions driving protected persulfide transfer in iron-sulfur cluster biogenesis.
J.Biol.Chem., 300, 2024
7REI
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BU of 7rei by Molmil
The crystal structure of nickel bound human ADO C18S C239S variant
Descriptor: 2-aminoethanethiol dioxygenase, GLYCEROL, NICKEL (II) ION
Authors:Wang, Y, Shin, I, Li, J, Liu, A.
Deposit date:2021-07-12
Release date:2021-09-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of human cysteamine dioxygenase provides a structural rationale for its function as an oxygen sensor.
J.Biol.Chem., 297, 2021
8BX5
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BU of 8bx5 by Molmil
Alvinella pompejana nicotinic acetylcholine receptor Alpo4 in apo state (dataset 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor
Authors:De Gieter, S, Efremov, R.G, Ulens, C.
Deposit date:2022-12-07
Release date:2023-07-12
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor.
Elife, 12, 2023
8BXD
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BU of 8bxd by Molmil
Alvinella pompejana nicotinic acetylcholine receptor Alpo4 in apo state (Alpo4_LMNG_Serotonin dataset 4)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor
Authors:De Gieter, S, Efremov, R.G, Ulens, C.
Deposit date:2022-12-08
Release date:2023-07-12
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor.
Elife, 12, 2023
8BXF
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BU of 8bxf by Molmil
Alvinella pompejana nicotinic acetylcholine receptor Alpo4 in apo state (Alpo4_apo, dataset 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor
Authors:De Gieter, S, Efremov, R.G, Ulens, C.
Deposit date:2022-12-08
Release date:2023-07-12
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor.
Elife, 12, 2023
8BXB
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BU of 8bxb by Molmil
Alvinella pompejana nicotinic acetylcholine receptor Alpo in apo state (dataset 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor
Authors:De Gieter, S, Efremov, R.G, Ulens, C.
Deposit date:2022-12-08
Release date:2023-07-12
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor.
Elife, 12, 2023
8BXE
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BU of 8bxe by Molmil
Alvinella pompejana nicotinic acetylcholine receptor Alpo4 in apo state (Alpo4_comb dataset 3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor
Authors:De Gieter, S, Efremov, R.G, Ulens, C.
Deposit date:2022-12-08
Release date:2023-07-12
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor.
Elife, 12, 2023
8BYI
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BU of 8byi by Molmil
Alvinella pompejana nicotinic acetylcholine receptor Alpo4 in complex with CHAPS(Alpo4_CHAPS)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Acetylcholine receptor, ...
Authors:De Gieter, S, Efremov, R.G, Ulens, C.
Deposit date:2022-12-13
Release date:2023-07-12
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor.
Elife, 12, 2023
3ZEI
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BU of 3zei by Molmil
Structure of the Mycobacterium tuberculosis O-Acetylserine Sulfhydrylase (OASS) CysK1 in complex with a small molecule inhibitor
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-[(Z)-[(5Z)-5-[[2-(2-hydroxy-2-oxoethyloxy)phenyl]methylidene]-3-methyl-4-oxidanylidene-1,3-thiazolidin-2-ylidene]amino]benzoic acid, O-ACETYLSERINE SULFHYDRYLASE, ...
Authors:Poyraz, O, Schnell, R, Schneider, G.
Deposit date:2012-12-05
Release date:2013-08-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Guided Design of Novel Thiazolidine Inhibitors of O-Acetyl Serine Sulfhydrylase from Mycobacterium Tuberculosis.
J.Med.Chem., 56, 2013

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