4CU7
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![BU of 4cu7 by Molmil](/molmil-images/mine/4cu7) | Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA | Descriptor: | 1,2-ETHANEDIOL, BETA-GALACTOSIDASE, D-galacto-isofagomine, ... | Authors: | Singh, A.K, Pluvinage, B, Higgins, M.A, Dalia, A.B, Flynn, M, Lloyd, A.R, Weiser, J.N, Stubbs, K.A, Boraston, A.B, King, S.J. | Deposit date: | 2014-03-17 | Release date: | 2014-08-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Unravelling the Multiple Functions of the Architecturally Intricate Streptococcus Pneumoniae Beta-Galactosidase, BgaA. Plos Pathog., 10, 2014
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4CKD
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4DUX
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![BU of 4dux by Molmil](/molmil-images/mine/4dux) | E. coli (lacZ) beta-galactosidase (N460S) in complex with L-ribose | Descriptor: | Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | Authors: | Wheatley, R.W, Lo, S, Janzcewicz, L.J, Dugdale, M.L, Huber, R.E. | Deposit date: | 2012-02-22 | Release date: | 2013-03-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural explanation for allolactose (lac operon inducer) synthesis by lacZ beta-galactosidase and the evolutionary relationship between allolactose synthesis and the lac repressor. J.Biol.Chem., 288, 2013
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6EC6
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![BU of 6ec6 by Molmil](/molmil-images/mine/6ec6) | Ruminococcus gnavus Beta-glucuronidase | Descriptor: | Beta-glucuronidase, CHLORIDE ION, GLYCEROL | Authors: | Biernat, K.A, Redinbo, M.R. | Deposit date: | 2018-08-07 | Release date: | 2019-02-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases. Sci Rep, 9, 2019
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6D6W
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![BU of 6d6w by Molmil](/molmil-images/mine/6d6w) | Bacteroides uniformis beta-glucuronidase 1 bound to glucuronate | Descriptor: | Beta-galactosidase/beta-glucuronidase, CHLORIDE ION, GLYCEROL, ... | Authors: | Walton, W.G, Pellock, S.J, Redinbo, M.R. | Deposit date: | 2018-04-23 | Release date: | 2018-10-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis. J. Biol. Chem., 293, 2018
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3OB8
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![BU of 3ob8 by Molmil](/molmil-images/mine/3ob8) | Structure of the beta-galactosidase from Kluyveromyces lactis in complex with galactose | Descriptor: | Beta-galactosidase, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Fernandez-Leiro, R, Pereira-Rodriguez, A, Becerra, M, Gonzalez-Siso, I, Cerdan, M.E, Sanz-Aparicio, J. | Deposit date: | 2010-08-06 | Release date: | 2011-08-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of specificity in tetrameric Kluyveromyces lactis beta-galactosidase. J.Struct.Biol., 177, 2012
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6D8G
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3MV1
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![BU of 3mv1 by Molmil](/molmil-images/mine/3mv1) | E.Coli (lacZ) beta-galactosidase (R599A) in complex with Guanidinium | Descriptor: | Beta-galactosidase, DIMETHYL SULFOXIDE, GUANIDINE, ... | Authors: | Dugdale, M.L, Vance, M, Driedger, M.L, Nibber, A, Tran, A, Huber, R.E. | Deposit date: | 2010-05-03 | Release date: | 2011-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Importance of Arg-599 of b-galactosidase (Escherichia coli) as an anchor for the open conformations of Phe-601 and the active-site loop Biochem.Cell Biol., 88, 2010
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6HPD
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![BU of 6hpd by Molmil](/molmil-images/mine/6hpd) | The structure of a beta-glucuronidase from glycoside hydrolase family 2 | Descriptor: | BROMIDE ION, Beta-galactosidase (GH2), MAGNESIUM ION | Authors: | Robb, C.S, Gerlach, N, Reisky, L, Bornshoeru, U, Hehemann, J.H. | Deposit date: | 2018-09-20 | Release date: | 2019-07-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | A marine bacterial enzymatic cascade degrades the algal polysaccharide ulvan. Nat.Chem.Biol., 15, 2019
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3MUZ
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![BU of 3muz by Molmil](/molmil-images/mine/3muz) | E.Coli (lacZ) beta-galactosidase (R599A) in complex with IPTG | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | Authors: | Dugdale, M.L, Vance, M.L, Driedger, M.R, Nibber, A, Tran, A, Huber, R.E. | Deposit date: | 2010-05-03 | Release date: | 2011-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Importance of Arg-599 of b-galactosidase (Escherichia coli) as an anchor for the open conformations of Phe-601 and the active-site loop Biochem.Cell Biol., 88, 2010
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6JZ8
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![BU of 6jz8 by Molmil](/molmil-images/mine/6jz8) | b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro 1,5-lactone | Descriptor: | (2S,3S,4S,5R)-3,4,5-trihydroxy-6-oxo-oxane-2-carboxylic acid, Beta-glucuronidase | Authors: | Dashnyam, P, Lin, H.Y. | Deposit date: | 2019-04-30 | Release date: | 2020-06-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.583 Å) | Cite: | Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes. J.Med.Chem., 63, 2020
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6JZ5
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6JZ3
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![BU of 6jz3 by Molmil](/molmil-images/mine/6jz3) | b-glucuronidase from Ruminococcus gnavus in complex with uronic deoxynojirimycin | Descriptor: | (2~{S},3~{R},4~{R},5~{S})-3,4,5-tris(oxidanyl)piperidine-2-carboxylic acid, (4R)-2-METHYLPENTANE-2,4-DIOL, Beta-glucuronidase | Authors: | Dashnyam, P, Lin, H.Y. | Deposit date: | 2019-04-30 | Release date: | 2020-05-13 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.502 Å) | Cite: | Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes. J.Med.Chem., 63, 2020
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3OBA
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![BU of 3oba by Molmil](/molmil-images/mine/3oba) | Structure of the beta-galactosidase from Kluyveromyces lactis | Descriptor: | Beta-galactosidase, GLYCEROL, MANGANESE (III) ION | Authors: | Fernandez-Leiro, R, Pereira-Rodriguez, A, Becerra, M, Gonzalez-Siso, I, Cerdan, M.E, Sanz-Aparicio, J. | Deposit date: | 2010-08-06 | Release date: | 2011-08-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural basis of specificity in tetrameric Kluyveromyces lactis beta-galactosidase. J.Struct.Biol., 177, 2012
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3MV0
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![BU of 3mv0 by Molmil](/molmil-images/mine/3mv0) | E. COLI (lacZ) BETA-GALACTOSIDASE (R599A) IN COMPLEX WITH D-GALCTOPYRANOSYL-1-ONE | Descriptor: | Beta-galactosidase, D-galactonolactone, DIMETHYL SULFOXIDE, ... | Authors: | Dugdale, M.L, Vance, M, Driedger, M.L, Nibber, A, Tran, A, Huber, R.E. | Deposit date: | 2010-05-03 | Release date: | 2011-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Importance of Arg-599 of b-galactosidase (Escherichia coli) as an anchor for the open conformations of Phe-601 and the active-site loop Biochem.Cell Biol., 88, 2010
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6JZ2
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![BU of 6jz2 by Molmil](/molmil-images/mine/6jz2) | b-glucuronidase from Ruminococcus gnavus in complex with uronic isofagomine at 1.3 Angstroms resolution | Descriptor: | (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ... | Authors: | Dashnyam, P, Lin, H.Y. | Deposit date: | 2019-04-30 | Release date: | 2020-06-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes. J.Med.Chem., 63, 2020
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6JZ4
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![BU of 6jz4 by Molmil](/molmil-images/mine/6jz4) | b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro-d-lactam | Descriptor: | (2S,3R,4S,5R)-3,4,5-trihydroxy-6-oxopiperidine-2-carboxylic acid, (4R)-2-METHYLPENTANE-2,4-DIOL, Beta-glucuronidase | Authors: | Dashnyam, P, Lin, H.Y. | Deposit date: | 2019-04-30 | Release date: | 2020-06-03 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.712 Å) | Cite: | Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes. J.Med.Chem., 63, 2020
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6JZ1
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6B6L
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![BU of 6b6l by Molmil](/molmil-images/mine/6b6l) | The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 | Descriptor: | 1,2-ETHANEDIOL, FORMIC ACID, Glycosyl hydrolase family 2, ... | Authors: | Tan, K, Joachimiak, G, Nocek, B, Enddres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2017-10-02 | Release date: | 2017-10-11 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 To Be Published
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6BJQ
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6BJW
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3T2Q
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![BU of 3t2q by Molmil](/molmil-images/mine/3t2q) | E. coli (lacZ) beta-galactosidase (S796D) in complex with galactonolactone | Descriptor: | Beta-galactosidase, D-galactonolactone, DIMETHYL SULFOXIDE, ... | Authors: | Jancewicz, L.J, Wheatley, R.W, Sutendra, G, Lee, M, Fraser, M, Huber, R.E. | Deposit date: | 2011-07-22 | Release date: | 2012-01-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Ser-796 of Beta-Galactosidase (E. coli) Plays a Key Role in Maintaining an Optimum Balance between the Opened and Closed Conformations of the Catalytically Important Active Site Loop Arch.Biochem.Biophys., 517, 2012
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6BO6
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![BU of 6bo6 by Molmil](/molmil-images/mine/6bo6) | Eubacterium eligens beta-glucuronidase bound to UNC4917 glucuronic acid conjugate | Descriptor: | 4-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-2,7-bis(methylamino)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine, Glycoside Hydrolase Family 2 candidate b-glucuronidase | Authors: | Pellock, S.J, Walton, W.G, Redinbo, M.R. | Deposit date: | 2017-11-18 | Release date: | 2018-07-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception. ACS Cent Sci, 4, 2018
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3SEP
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![BU of 3sep by Molmil](/molmil-images/mine/3sep) | E. coli (lacZ) beta-galactosidase (S796A) | Descriptor: | Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | Authors: | Jancewicz, L.J, Wheatley, R.W, Sutendra, G, Lee, M, Fraser, M, Huber, R.E. | Deposit date: | 2011-06-10 | Release date: | 2012-01-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Ser-796 of Beta-Galactosidase (E. coli) Plays a Key Role in Maintaining an Optimum Balance between the Opened and Closed Conformations of the Catalytically Important Active Site Loop Arch.Biochem.Biophys., 517, 2012
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6D1N
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