6BO6

Eubacterium eligens beta-glucuronidase bound to UNC4917 glucuronic acid conjugate

Summary for 6BO6

Entry DOI	10.2210/pdb6bo6/pdb
Descriptor	Glycoside Hydrolase Family 2 candidate b-glucuronidase, 4-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-2,7-bis(methylamino)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine (3 entities in total)
Functional Keywords	glycosyl hydrolase, beta-glucuronidase, hormone, hydrolase
Biological source	Eubacterium eligens (strain ATCC 27750 / VPI C15-48)
Total number of polymer chains	1
Total formula weight	70111.46
Authors	Pellock, S.J.,Walton, W.G.,Redinbo, M.R. (deposition date: 2017-11-18, release date: 2018-07-25, Last modification date: 2024-03-13)
Primary citation	Pellock, S.J.,Creekmore, B.C.,Walton, W.G.,Mehta, N.,Biernat, K.A.,Cesmat, A.P.,Ariyarathna, Y.,Dunn, Z.D.,Li, B.,Jin, J.,James, L.I.,Redinbo, M.R. Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception. ACS Cent Sci, 4:868-879, 2018 Cited by PubMed: 30062115 DOI: 10.1021/acscentsci.8b00239 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.801 Å)

Structure validation