3MUZ

E.Coli (lacZ) beta-galactosidase (R599A) in complex with IPTG

Summary for 3MUZ

• Entry DOI: 10.2210/pdb3muz/pdb
• Related: 1DP0 1JYX 1JZ5 1PX3 1PX4 3MV0 3MV1
• Descriptor: Beta-galactosidase, 1-methylethyl 1-thio-beta-D-galactopyranoside, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: arg-599-ala, beta-galactosidase, hydrolase tim barrel(alpha/beta barrel), jelly-roll barrel, immunoglobulin beta supersandwhich, glycosidase, hydrolase
• Biological source: Escherichia coli
• Total number of polymer chains: 4
• Total formula weight: 492965.00

Authors

Dugdale, M.L.,Vance, M.L.,Driedger, M.R.,Nibber, A.,Tran, A.,Huber, R.E. (deposition date: 2010-05-03, release date: 2011-03-16, Last modification date: 2023-09-06)

• Primary citation: Dugdale, M.L.,Vance, M.L.,Wheatley, R.W.,Driedger, M.R.,Nibber, A.,Tran, A.,Huber, R.E.; Importance of Arg-599 of b-galactosidase (Escherichia coli) as an anchor for the open conformations of Phe-601 and the active-site loop; Biochem.Cell Biol., 88:969-979, 2010

Experimental method

X-RAY DIFFRACTION (1.9 Å)