2WB1
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![BU of 2wb1 by Molmil](/molmil-images/mine/2wb1) | The complete structure of the archaeal 13-subunit DNA-directed RNA Polymerase | Descriptor: | DNA-DIRECTED RNA POLYMERASE RPO10 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO11 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO12 SUBUNIT, ... | Authors: | Korkhin, Y, Unligil, U.M, Littlefield, O, Nelson, P.J, Stuart, D.I, Sigler, P.B, Bell, S.D, Abrescia, N.G.A. | Deposit date: | 2009-02-19 | Release date: | 2009-05-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.52 Å) | Cite: | Evolution of Complex RNA Polymerase: The Complete Archaeal RNA Polymerase Structure Plos Biol., 7, 2009
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2VUM
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![BU of 2vum by Molmil](/molmil-images/mine/2vum) | Alpha-amanitin inhibited complete RNA polymerase II elongation complex | Descriptor: | 5'-D(*AP*AP*AP*CP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *GP*TP*TP*AP*CP*GP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ... | Authors: | Brueckner, F, Cramer, P. | Deposit date: | 2008-05-27 | Release date: | 2008-06-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural Basis of Transcription Inhibition by Alpha-Amanitin and Implications for RNA Polymerase II Translocation. Nat.Struct.Mol.Biol., 15, 2008
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2WAQ
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![BU of 2waq by Molmil](/molmil-images/mine/2waq) | The complete structure of the archaeal 13-subunit DNA-directed RNA Polymerase | Descriptor: | DNA-DIRECTED RNA POLYMERASE RPO10 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO11 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO12 SUBUNIT, ... | Authors: | Korkhin, Y, Unligil, U.M, Littlefield, O, Nelson, P.J, Stuart, D.I, Sigler, P.B, Bell, S.D, Abrescia, N.G.A. | Deposit date: | 2009-02-11 | Release date: | 2009-05-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Evolution of complex RNA polymerases: the complete archaeal RNA polymerase structure. Plos Biol., 7, 2009
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2Y0S
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![BU of 2y0s by Molmil](/molmil-images/mine/2y0s) | Crystal structure of Sulfolobus shibatae RNA polymerase in P21 space group | Descriptor: | DNA-DIRECTED RNA POLYMERASE, DNA-DIRECTED RNA POLYMERASE SUBUNIT A'', DNA-DIRECTED RNA POLYMERASE SUBUNIT D, ... | Authors: | Wojtas, M, Peralta, B, Ondiviela, M, Mogni, M, Bell, S.D, Abrescia, N.G.A. | Deposit date: | 2010-12-07 | Release date: | 2011-02-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Archaeal RNA polymerase: the influence of the protruding stalk in crystal packing and preliminary biophysical analysis of the Rpo13 subunit. Biochem. Soc. Trans., 39, 2011
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4NBQ
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![BU of 4nbq by Molmil](/molmil-images/mine/4nbq) | Structure of the polynucleotide phosphorylase (CBU_0852) from Coxiella burnetii | Descriptor: | Polyribonucleotide nucleotidyltransferase, SULFATE ION | Authors: | Rudolph, M.J, Cheung, J, Franklin, M.C, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | Deposit date: | 2013-10-23 | Release date: | 2015-06-17 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.9138 Å) | Cite: | Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
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6TQN
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![BU of 6tqn by Molmil](/molmil-images/mine/6tqn) | rrn anti-termination complex without S4 | Descriptor: | 30S ribosomal protein S10, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. | Deposit date: | 2019-12-17 | Release date: | 2020-08-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
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6TQO
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![BU of 6tqo by Molmil](/molmil-images/mine/6tqo) | rrn anti-termination complex | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S4, DNA-directed RNA polymerase subunit alpha, ... | Authors: | Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. | Deposit date: | 2019-12-17 | Release date: | 2020-08-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
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6SW9
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![BU of 6sw9 by Molmil](/molmil-images/mine/6sw9) | IC2A model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid of aIF1 in P. abyssi | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Coureux, P.-D, Mechulam, Y, Schmitt, E. | Deposit date: | 2019-09-20 | Release date: | 2020-02-19 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation. Commun Biol, 3, 2020
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6TED
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![BU of 6ted by Molmil](/molmil-images/mine/6ted) | Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1 | Descriptor: | DNA (37-MER), DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, ... | Authors: | Vos, S.M, Farnung, L, Cramer, P. | Deposit date: | 2019-11-11 | Release date: | 2020-07-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation. Nat.Struct.Mol.Biol., 27, 2020
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6SWC
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![BU of 6swc by Molmil](/molmil-images/mine/6swc) | IC2B model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid of aIF1 in P. abyssi | Descriptor: | 16S ribosomal rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Coureux, P.-D, Mechulam, Y, Schmitt, E. | Deposit date: | 2019-09-20 | Release date: | 2020-02-19 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation. Commun Biol, 3, 2020
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6RXZ
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![BU of 6rxz by Molmil](/molmil-images/mine/6rxz) | Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state b | Descriptor: | 35S ribosomal RNA, 40S ribosomal protein S11-like protein, 40S ribosomal protein S13-like protein, ... | Authors: | Cheng, J, Kellner, N, Griesel, S, Berninghausen, O, Beckmann, R, Hurt, E. | Deposit date: | 2019-06-10 | Release date: | 2019-08-14 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration. Mol.Cell, 75, 2019
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6RXY
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![BU of 6rxy by Molmil](/molmil-images/mine/6rxy) | Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state a | Descriptor: | 35S rRNA, 40S ribosomal protein S13-like protein, 40S ribosomal protein S14-like protein, ... | Authors: | Cheng, J, Kellner, N, Griesel, S, Berninghausen, O, Beckmann, R, Hurt, E. | Deposit date: | 2019-06-10 | Release date: | 2019-08-14 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration. Mol.Cell, 75, 2019
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8BYQ
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![BU of 8byq by Molmil](/molmil-images/mine/8byq) | RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W) | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. | Deposit date: | 2022-12-14 | Release date: | 2023-05-03 | Last modified: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Mol.Cell, 83, 2023
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8CAS
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![BU of 8cas by Molmil](/molmil-images/mine/8cas) | Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | Authors: | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | Deposit date: | 2023-01-24 | Release date: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
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8C6J
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![BU of 8c6j by Molmil](/molmil-images/mine/8c6j) | Human spliceosomal PM5 C* complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Dybkov, O, Kastner, B, Luehrmann, R. | Deposit date: | 2023-01-12 | Release date: | 2023-07-12 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins. Sci Adv, 9, 2023
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8CEE
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![BU of 8cee by Molmil](/molmil-images/mine/8cee) | Rnase R bound to a 30S degradation intermediate (State I - head-turning) | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | Deposit date: | 2023-02-01 | Release date: | 2023-12-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
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8CED
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![BU of 8ced by Molmil](/molmil-images/mine/8ced) | Rnase R bound to a 30S degradation intermediate (State I - head-turning) | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | Deposit date: | 2023-02-01 | Release date: | 2023-12-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.15 Å) | Cite: | Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
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8CDU
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![BU of 8cdu by Molmil](/molmil-images/mine/8cdu) | Rnase R bound to a 30S degradation intermediate (main state) | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | Deposit date: | 2023-02-01 | Release date: | 2023-12-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
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8CEC
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![BU of 8cec by Molmil](/molmil-images/mine/8cec) | Rnase R bound to a 30S degradation intermediate (State I - head-turning) | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | Deposit date: | 2023-02-01 | Release date: | 2023-12-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
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8CDV
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![BU of 8cdv by Molmil](/molmil-images/mine/8cdv) | Rnase R bound to a 30S degradation intermediate (state II) | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | Deposit date: | 2023-02-01 | Release date: | 2023-12-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.73 Å) | Cite: | Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
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7D63
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![BU of 7d63 by Molmil](/molmil-images/mine/7d63) | Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Du, Y, Zhang, J, An, W, Ye, K. | Deposit date: | 2020-09-29 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (12.3 Å) | Cite: | Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) To Be Published
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7D4I
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![BU of 7d4i by Molmil](/molmil-images/mine/7d4i) | Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA helicase Dhr1 (State F) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Du, Y, Zhang, J, An, W, Ye, K. | Deposit date: | 2020-09-24 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structure of 90S small ribosomal precursors complex with Dhr1 To Be Published
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7D5S
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![BU of 7d5s by Molmil](/molmil-images/mine/7d5s) | Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S12, ... | Authors: | Du, Y, Zhang, J, An, W, Ye, K. | Deposit date: | 2020-09-28 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2) To Be Published
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7D5T
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![BU of 7d5t by Molmil](/molmil-images/mine/7d5t) | Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Du, Y, Zhang, J, An, W, Ye, K. | Deposit date: | 2020-09-28 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1) To Be Published
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7SYR
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![BU of 7syr by Molmil](/molmil-images/mine/7syr) | Structure of the wt IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(wt). | Descriptor: | 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ... | Authors: | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | Deposit date: | 2021-11-25 | Release date: | 2022-07-27 | Last modified: | 2022-08-24 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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