PDB: 929 resultsInfo pagesStatus searchChemie searchBIRD

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6NX5	Crystal structure of the RRM domain of S. pombe Puf1 in the P21 space group Descriptor: 1,2-ETHANEDIOL, Pumilio domain-containing protein C56F2.08c Authors: Qiu, C, Hall, T.M.T. Deposit date: 2019-02-08 Release date: 2019-07-03 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.554 Å) Cite: Distinct RNA-binding modules in a single PUF protein cooperate to determine RNA specificity. Nucleic Acids Res., 47, 2019
6XH2	Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM 6.6 Descriptor: TAR-BINDING PROTEIN 6.6, TRANS-ACTIVATION RESPONSE ELEMENT Authors: Chavali, S.S, Jenkins, J.L, Wedekind, J.E. Deposit date: 2020-06-18 Release date: 2020-10-14 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors. J.Biol.Chem., 295, 2020
6XLV	Crystal structure of leukemia-associated N196K mutant of U2AF65 bound to AdML splice site Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit Authors: Maji, D, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2020-06-29 Release date: 2020-10-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing. J.Biol.Chem., 295, 2020
1NO8	SOLUTION STRUCTURE OF THE NUCLEAR FACTOR ALY RBD DOMAIN Descriptor: ALY Authors: Perez-Alvarado, G.C, Martinez-Yamout, M, Allen, M.M, Grosschedl, R, Dyson, H.J, Wright, P.E. Deposit date: 2003-01-15 Release date: 2003-08-12 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structure of the Nuclear Factor ALY: Insights into Post-Transcriptional Regulatory and mRNA Nuclear Export Processes Biochemistry, 42, 2003
1NU4	U1A RNA binding domain at 1.8 angstrom resolution reveals a pre-organized C-terminal helix Descriptor: MAGNESIUM ION, MALONIC ACID, U1A RNA binding domain Authors: Rupert, P.B, Xiao, H, Ferre-D'Amare, A.R. Deposit date: 2003-01-30 Release date: 2003-02-14 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.8 Å) Cite: U1A RNA-binding domain at 1.8 A resolution. Acta Crystallogr.,Sect.D, 59, 2003
6SR7	Structure of the U1A variant A1-98 Y31H/Q36R/K98W Descriptor: SULFATE ION, U1 small nuclear ribonucleoprotein A Authors: Rosenbach, H, Span, I. Deposit date: 2019-09-05 Release date: 2020-05-13 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Expanding crystallization tools for nucleic acid complexes using U1A protein variants. J.Struct.Biol., 210, 2020
6N3E	Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to U2AF ligand motif 4 Descriptor: FORMIC ACID, GLYCEROL, HIV Tat-specific factor 1, ... Authors: Loerch, S, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2018-11-15 Release date: 2019-01-02 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.893 Å) Cite: The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface. J. Biol. Chem., 294, 2019
1P1T	NMR Structure of the N-terminal RRM domain of Cleavage stimulation factor 64 KDa subunit Descriptor: Cleavage stimulation factor, 64 kDa subunit Authors: Perez-Canadillas, J.M, Varani, G. Deposit date: 2003-04-14 Release date: 2003-08-12 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein Embo J., 22, 2003
6XLX	Crystal structure of cancer-associated G301D mutant of U2AF65 bound to AdML splice site Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit Authors: Maji, D, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2020-06-29 Release date: 2020-10-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing. J.Biol.Chem., 295, 2020
6XH1	Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM TBP6.7 mutant Descriptor: TAR binding protein mutant 6.7 Q48R/T50R, TRANS-ACTIVATION RESPONSE ELEMENT Authors: Chavali, S.S, Jenkins, J.L, Wedekind, J.E. Deposit date: 2020-06-18 Release date: 2020-10-14 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.601 Å) Cite: Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors. J.Biol.Chem., 295, 2020
6XLW	Crystal structure of U2AF65 bound to AdML splice site sequence Descriptor: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), GLYCEROL, ... Authors: Maji, D, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2020-06-29 Release date: 2020-10-07 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing. J.Biol.Chem., 295, 2020
6XH0	Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM TBP6.9 Descriptor: MAGNESIUM ION, TAR binding protein 6.9, TRANS-ACTIVATION RESPONSE ELEMENT Authors: Chavali, S.S, Jenkins, J.L, Wedekind, J.E. Deposit date: 2020-06-18 Release date: 2020-10-14 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors. J.Biol.Chem., 295, 2020
1OPI	SOLUTION STRUCTURE OF THE THIRD RNA RECOGNITION MOTIF (RRM) OF U2AF65 IN COMPLEX WITH AN N-TERMINAL SF1 PEPTIDE Descriptor: SPLICING FACTOR SF1, SPLICING FACTOR U2AF 65 KDA SUBUNIT Authors: Selenko, P, Gregorovic, G, Sprangers, R, Stier, G, Rhani, Z, Kramer, A, Sattler, M. Deposit date: 2003-03-05 Release date: 2004-03-16 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP Mol.Cell, 11, 2003
7VSJ	Crystal structure of MmIMP3-RRM12 in complex with 9-mer RNA Descriptor: Insulin-like growth factor 2 mRNA-binding protein 3, RNA (9-mer) Authors: Li, X.J, Wu, B.X. Deposit date: 2021-10-26 Release date: 2022-11-02 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Crystal structure of MmIMP3-RRM12 in complex with 9-mer RNA To Be Published
7VRL	Solution structure of Rbfox RRM bound to a non-cognate RNA Descriptor: RNA (5'-R(*UP*GP*CP*AP*UP*AP*U)-3'), RNA binding protein fox-1 homolog 1 Authors: Yang, F, Varani, G. Deposit date: 2021-10-23 Release date: 2022-10-26 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Two distinct binding modes provide the RNA-binding protein RbFox with extraordinary sequence specificity. Nat Commun, 14, 2023
1PO6	Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI) Descriptor: 5'-D(*T*AP*GP*GP*(6MI)P*TP*TP*AP*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1 Authors: Myers, J.C, Moore, S.A, Shamoo, Y. Deposit date: 2003-06-13 Release date: 2003-11-11 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures J.BIOL.CHEM., 278, 2003
1RKJ	Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target Descriptor: 5'-R(*GP*GP*AP*UP*GP*CP*CP*UP*CP*CP*CP*GP*AP*GP*UP*GP*CP*AP*UP*CP*C)-3', Nucleolin Authors: Johansson, C, Finger, L.D, Trantirek, L, Mueller, T.D, Kim, S, Laird-Offringa, I.A, Feigon, J. Deposit date: 2003-11-21 Release date: 2004-04-27 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target. J.Mol.Biol., 337, 2004
2RNE	Solution structure of the second RNA recognition motif (RRM) of TIA-1 Descriptor: Tia1 protein Authors: Takahashi, M, Kuwasako, K, Abe, C, Tsuda, K, Inoue, M, Terada, T, Shirouzu, M, Kobayashi, N, Kigawa, T, Taguchi, S, Guntert, P, Hayashizaki, Y, Tanaka, A, Muto, Y, Yokoyama, S. Deposit date: 2007-12-19 Release date: 2008-11-04 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the second RNA recognition motif (RRM) domain of murine T cell intracellular antigen-1 (TIA-1) and its RNA recognition mode Biochemistry, 47, 2008
2RS8	Solution structure of the N-terminal RNA recognition motif of NonO Descriptor: Non-POU domain-containing octamer-binding protein Authors: Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2011-11-29 Release date: 2012-12-19 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Solution structure of the N-terminal RNA recognition motif of NonO To be Published
3EGZ	Crystal structure of an in vitro evolved tetracycline aptamer and artificial riboswitch Descriptor: 7-CHLOROTETRACYCLINE, MAGNESIUM ION, Tetracycline aptamer and artificial riboswitch, ... Authors: Xiao, H, Edwards, T.E, Ferre-D'Amare, A.R. Deposit date: 2008-09-11 Release date: 2008-10-28 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis for specific, high-affinity tetracycline binding by an in vitro evolved aptamer and artificial riboswitch Chem.Biol., 15, 2008
2RRA	Solution structure of RNA binding domain in human Tra2 beta protein in complex with RNA (GAAGAA) Descriptor: 5'-R(*GP*AP*AP*GP*AP*A)-3', cDNA FLJ40872 fis, clone TUTER2000283, ... Authors: Tsuda, K, Kuwasako, K, Takahashi, M, Someya, T, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Sugano, S, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2010-06-17 Release date: 2011-04-27 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural basis for the dual RNA-recognition modes of human Tra2-beta RRM. Nucleic Acids Res., 39, 2011
2RS2	1H, 13C, and 15N Chemical Shift Assignments for Musashi1 RBD1:r(GUAGU) complex Descriptor: RNA (5'-R(*GP*UP*AP*GP*U)-3'), RNA-binding protein Musashi homolog 1 Authors: Ohyama, T, Nagata, T, Tsuda, K, Imai, T, Okano, H, Yamazaki, T, Katahira, M. Deposit date: 2011-06-27 Release date: 2011-12-28 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structure of Musashi1 in a complex with target RNA: the role of aromatic stacking interactions Nucleic Acids Res., 2011
2RQ4	Refinement of RNA binding domain 3 in CUG triplet repeat RNA-binding protein 1 Descriptor: CUG-BP- and ETR-3-like factor 1 Authors: Tsuda, K, Kuwasako, K, Takahashi, M, Someya, T, Inoue, M, Terada, T, Kobayashi, N, Shirouzu, M, Kigawa, T, Guntert, P, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2009-01-19 Release date: 2009-08-04 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Structural basis for the sequence-specific RNA-recognition mechanism of human CUG-BP1 RRM3 Nucleic Acids Res., 2009
2UP1	STRUCTURE OF UP1-TELOMERIC DNA COMPLEX Descriptor: DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), PROTEIN (HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1) Authors: Ding, J, Hayashi, M.K, Krainer, A.R, Xu, R.-M. Deposit date: 1998-07-10 Release date: 1999-11-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with single-stranded telomeric DNA. Genes Dev., 13, 1999
2RQC	Solution Structure of RNA-binding domain 3 of CUGBP1 in complex with RNA (UG)3 Descriptor: 5'-R(*UP*GP*UP*GP*UP*G)-3', CUG-BP- and ETR-3-like factor 1 Authors: Tsuda, K, Kuwasako, K, Takahashi, M, Someya, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2009-04-09 Release date: 2009-08-04 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Structural basis for the sequence-specific RNA-recognition mechanism of human CUG-BP1 RRM3 Nucleic Acids Res., 37, 2009

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