5OBN
NMR solution structure of U11/U12 65K protein's C-terminal RRM domain (381-516)
Summary for 5OBN
Entry DOI | 10.2210/pdb5obn/pdb |
NMR Information | BMRB: 34155 |
Descriptor | RNA-binding protein 40 (1 entity in total) |
Functional Keywords | minor spliceosome, rna binding, splicing |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 15796.29 |
Authors | Norppa, A.J.,Kauppala, T.M.,Heikkinen, H.A.,Verma, B.,Iwai, H.,Frilander, M.J. (deposition date: 2017-06-28, release date: 2018-01-24, Last modification date: 2024-06-19) |
Primary citation | Norppa, A.J.,Kauppala, T.M.,Heikkinen, H.A.,Verma, B.,Iwai, H.,Frilander, M.J. Mutations in the U11/U12-65K protein associated with isolated growth hormone deficiency lead to structural destabilization and impaired binding of U12 snRNA. RNA, 24:396-409, 2018 Cited by PubMed: 29255062DOI: 10.1261/rna.062844.117 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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