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5OBN

NMR solution structure of U11/U12 65K protein's C-terminal RRM domain (381-516)

Summary for 5OBN
Entry DOI10.2210/pdb5obn/pdb
NMR InformationBMRB: 34155
DescriptorRNA-binding protein 40 (1 entity in total)
Functional Keywordsminor spliceosome, rna binding, splicing
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight15796.29
Authors
Norppa, A.J.,Kauppala, T.M.,Heikkinen, H.A.,Verma, B.,Iwai, H.,Frilander, M.J. (deposition date: 2017-06-28, release date: 2018-01-24, Last modification date: 2023-06-14)
Primary citationNorppa, A.J.,Kauppala, T.M.,Heikkinen, H.A.,Verma, B.,Iwai, H.,Frilander, M.J.
Mutations in the U11/U12-65K protein associated with isolated growth hormone deficiency lead to structural destabilization and impaired binding of U12 snRNA.
RNA, 24:396-409, 2018
Cited by
PubMed: 29255062
DOI: 10.1261/rna.062844.117
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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