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4PMT
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BU of 4pmt by Molmil
The structure of TrkA kinase bound to the inhibitor N~4~-(4-morpholin-4-ylphenyl)-N~6~-(pyridin-3-ylmethyl)pyrido[3,2-d]pyrimidine-4,6-diamine
Descriptor: ACETATE ION, CHLORIDE ION, High affinity nerve growth factor receptor, ...
Authors:Su, H.P.
Deposit date:2014-05-22
Release date:2014-06-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic pain.
J.Med.Chem., 57, 2014
4PER
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BU of 4per by Molmil
Structure of Gallus gallus ribonuclease inhibitor complexed with Gallus gallus ribonuclease I
Descriptor: Angiogenin, Ribonuclease Inhibitor
Authors:Bianchetti, C.M, Lomax, J.E, Raines, R.T, Fox, B.G.
Deposit date:2014-04-24
Release date:2014-06-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Functional evolution of ribonuclease inhibitor: insights from birds and reptiles.
J.Mol.Biol., 426, 2014
4PEQ
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BU of 4peq by Molmil
Structure of bovine ribonuclease inhibitor complexed with bovine ribonuclease I
Descriptor: Ribonuclease pancreatic, Ribonuclease/angiogenin inhibitor 1
Authors:Bianchetti, C.M, Lomax, J.E, Raines, R.T, Fox, B.G.
Deposit date:2014-04-24
Release date:2014-06-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.211 Å)
Cite:Functional evolution of ribonuclease inhibitor: insights from birds and reptiles.
J.Mol.Biol., 426, 2014
3TSR
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BU of 3tsr by Molmil
X-ray structure of mouse ribonuclease inhibitor complexed with mouse ribonuclease 1
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ribonuclease inhibitor, ...
Authors:Chang, A, Lomax, J.E, Bingman, C.A, Raines, R.T, Phillips Jr, G.N.
Deposit date:2011-09-13
Release date:2012-09-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1999 Å)
Cite:Functional evolution of ribonuclease inhibitor: insights from birds and reptiles.
J.Mol.Biol., 426, 2014
5T1Z
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BU of 5t1z by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Ethoxytriphenylethylene and GRIP Peptide
Descriptor: 4,4'-[(1Z)-1-(4-ethoxyphenyl)but-1-ene-1,2-diyl]diphenol, Estrogen receptor, Nuclear receptor coactivator 2
Authors:Fanning, S.W, Rajan, S.S, Maximov, P.Y, Abderrahman, B.H, Surojeet, S, Fernandes, D.J, Fan, P, Curpan, R.F, Greene, G.L, Jordan, V.C.
Deposit date:2016-08-22
Release date:2017-08-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.
Mol. Pharmacol., 94, 2018
2ON8
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BU of 2on8 by Molmil
Gbeta1 stabilization by in vitro evolution and computational design
Descriptor: Immunoglobulin G-binding protein G
Authors:Max, K.E.A, Heinemann, U.
Deposit date:2007-01-23
Release date:2007-12-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Optimization of the gbeta1 domain by computational design and by in vitro evolution: structural and energetic basis of stabilization.
J.Mol.Biol., 373, 2007
2ONQ
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BU of 2onq by Molmil
Gbeta1 stabilization by in vitro evolution and computational design
Descriptor: Immunoglobulin G-binding protein G
Authors:Max, K.E.A, Heinemann, U.
Deposit date:2007-01-24
Release date:2008-01-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Optimization of the gbeta1 domain by computational design and by in vitro evolution: structural and energetic basis of stabilization.
J.Mol.Biol., 373, 2007
3JZ7
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BU of 3jz7 by Molmil
Crystal structure of the extracellular domains of coxsackie & adenovirus receptor from mouse (mCAR)
Descriptor: Coxsackievirus and adenovirus receptor homolog, ISOPROPYL ALCOHOL
Authors:Max, K.E.A, Heinemann, U.
Deposit date:2009-09-23
Release date:2010-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The coxsackievirus-adenovirus receptor reveals complex homophilic and heterophilic interactions on neural cells.
J.Neurosci., 30, 2010
3FIL
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BU of 3fil by Molmil
Structural and energetic determinants for hyperstable variants of GB1 obtained from in-vitro evolution
Descriptor: CALCIUM ION, Immunoglobulin G-binding protein G
Authors:Max, K.E.A, Heinemann, U.
Deposit date:2008-12-12
Release date:2009-08-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (0.88 Å)
Cite:Dimer Formation of a Stabilized Gbeta1 Variant: A Structural and Energetic Analysis
J.Mol.Biol., 391, 2009
5HYW
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BU of 5hyw by Molmil
The crystal structure of the D3-ASK1 complex
Descriptor: F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A
Authors:Yao, R.F, Ming, Z.H, Yan, L.M, Rao, Z.H, Lou, Z.Y, Xie, D.X.
Deposit date:2016-02-02
Release date:2016-08-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:DWARF14 is a non-canonical hormone receptor for strigolactone
Nature, 536, 2016
2LW5
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BU of 2lw5 by Molmil
Solution structure of anti-CRISPR protein Acr30-35 from Pseudomonas aeruginosa Phage JBD30
Descriptor: ACR30-35
Authors:Maxwell, K.L, Bondy-Denomy, J, Davidson, A.R.
Deposit date:2012-07-22
Release date:2014-01-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Discovery of phage genes that allow evasion of the CRISPR/Cas bacterial immune system
To be Published
2KX4
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BU of 2kx4 by Molmil
Solution structure of Bacteriophage Lambda gpFII
Descriptor: Tail attachment protein
Authors:Maxwell, K.L, Cardarelli, L, Neudecker, P, Davidson, A.R, Ontario Centre for Structural Proteomics (OCSP)
Deposit date:2010-04-26
Release date:2010-07-28
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Phages have adapted the same protein fold to fulfill multiple functions in virion assembly.
Proc.Natl.Acad.Sci.USA, 107, 2010
3UKX
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BU of 3ukx by Molmil
Mouse importin alpha: Bimax2 peptide complex
Descriptor: Bimax2 peptide, Importin subunit alpha-2
Authors:Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
Deposit date:2011-11-10
Release date:2012-10-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
6Y4C
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BU of 6y4c by Molmil
Structure of galectin-3C in complex with lactose determined by serial crystallography using an XtalTool support
Descriptor: CHLORIDE ION, Galectin-3, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Shilova, A, Hakansson, M, Welin, M, Kovacic, R, Mueller, U, Logan, D.T.
Deposit date:2020-02-20
Release date:2020-06-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Current status and future opportunities for serial crystallography at MAX IV Laboratory.
J.Synchrotron Radiat., 27, 2020
6Y2N
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BU of 6y2n by Molmil
Crystal structure of ribonucleotide reductase R2 subunit solved by serial synchrotron crystallography
Descriptor: FE (III) ION, MANGANESE (III) ION, Ribonucleoside-diphosphate reductase subunit beta
Authors:Shilova, A, Lebrette, H, Aurelius, O, Hogbom, M, Mueller, U.
Deposit date:2020-02-17
Release date:2020-10-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Current status and future opportunities for serial crystallography at MAX IV Laboratory.
J.Synchrotron Radiat., 27, 2020
6Y78
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BU of 6y78 by Molmil
Structure of galectin-3C in complex with lactose determined by serial crystallography using a silicon nitride membrane support
Descriptor: Galectin-3, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Hakansson, M, Welin, M, Shilova, A, Kovacic, R, Mueller, U, Logan, D.T.
Deposit date:2020-02-28
Release date:2020-07-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Current status and future opportunities for serial crystallography at MAX IV Laboratory.
J.Synchrotron Radiat., 27, 2020
5ZNE
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BU of 5zne by Molmil
The crystal structure of immune receptor RGA5A_S of resistance protein Pia from rice (Oryza sativa)
Descriptor: NBS-LRR type protein
Authors:Guo, L.W, Huang, D, Liu, J.F, Peng, Y.L.
Deposit date:2018-04-09
Release date:2018-10-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Specific recognition of two MAX effectors by integrated HMA domains in plant immune receptors involves distinct binding surfaces
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5ZNG
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BU of 5zng by Molmil
The crystal complex of immune receptor RGA5A_S of Pia from rice (Oryzae sativa) with rice blast (Magnaporthe oryzae) effector protein AVR1-CO39
Descriptor: AVR1-CO39, NBS-LRR type protein
Authors:Guo, L.W, Zhang, Y.K, Liu, Q, Ma, M.Q, Liu, J.F, Peng, Y.L.
Deposit date:2018-04-09
Release date:2018-10-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.189 Å)
Cite:Specific recognition of two MAX effectors by integrated HMA domains in plant immune receptors involves distinct binding surfaces
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6R5J
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BU of 6r5j by Molmil
New MAX Effector from Magnaporthe oryzae
Descriptor: HEXAETHYLENE GLYCOL, Uncharacterized protein
Authors:Hoh, F, Padilla, A, De Guillen, K.
Deposit date:2019-03-25
Release date:2020-05-06
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:New MAX Effector from Magnaporthe oryzae
To Be Published
3KAJ
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BU of 3kaj by Molmil
Apoenzyme structure of homoglutathione synthetase from Glycine max in open conformation
Descriptor: Homoglutathione synthetase
Authors:Galant, A, Arkus, K.A.J, Zubieta, C, Cahoon, R.E, Jez, J.M.
Deposit date:2009-10-19
Release date:2009-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Evolution of Product Diversity in Soybean Glutathione Biosynthesis.
Plant Cell, 21, 2009
3KAK
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BU of 3kak by Molmil
Structure of homoglutathione synthetase from Glycine max in open conformation with gamma-glutamyl-cysteine bound.
Descriptor: GAMMA-GLUTAMYLCYSTEINE, Homoglutathione synthetase
Authors:Galant, A, Arkus, K.A.J, Zubieta, C, Cahoon, R.E, Jez, J.M.
Deposit date:2009-10-19
Release date:2009-12-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structural Basis for Evolution of Product Diversity in Soybean Glutathione Biosynthesis.
Plant Cell, 21, 2009
1JZU
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BU of 1jzu by Molmil
Cell transformation by the myc oncogene activates expression of a lipocalin: analysis of the gene (Q83) and solution structure of its protein product
Descriptor: lipocalin Q83
Authors:Hartl, M, Matt, T, Schueler, W, Siemeister, G, Kontaxis, G, Kloiber, K, Konrat, R, Bister, K.
Deposit date:2001-09-17
Release date:2003-07-15
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Cell Transformation by the v-myc Oncogene Abrogates c-Myc/Max-mediated Suppression of a C/EBPbeta-dependent Lipocalin Gene.
J.Mol.Biol., 333, 2003
5L7A
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BU of 5l7a by Molmil
The crystal structure of the Human SNF5/INI1 domain
Descriptor: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
Authors:Allen, M.D, Zinzalla, G, Bycroft, M.
Deposit date:2016-06-02
Release date:2017-05-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:The structure of INI1/hSNF5 RPT1 and its interactions with the c-MYC:MAX heterodimer provide insights into the interplay between MYC and the SWI/SNF chromatin remodeling complex.
FEBS J., 285, 2018
7RCU
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BU of 7rcu by Molmil
Synthetic Max homodimer mimic in complex with DNA
Descriptor: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, 2-(2,5-dioxopyrrolidin-1-yl)acetamide, ACETAMIDE, ...
Authors:Speltz, T, Qiao, Z, Shangguan, S, Fanning, S, Greene, J, Moellering, R.
Deposit date:2021-07-08
Release date:2022-09-14
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Targeting MYC with modular synthetic transcriptional repressors derived from bHLH DNA-binding domains.
Nat.Biotechnol., 41, 2023
5L7B
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BU of 5l7b by Molmil
Solution structure of the human SNF5/INI1 domain
Descriptor: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
Authors:Allen, M.D, Zinzalla, G, Bycroft, M.
Deposit date:2016-06-02
Release date:2017-05-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The structure of INI1/hSNF5 RPT1 and its interactions with the c-MYC:MAX heterodimer provide insights into the interplay between MYC and the SWI/SNF chromatin remodeling complex.
FEBS J., 285, 2018

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