PDB: 35140 resultsInfo pagesStatus searchChemie searchBIRD

---

7PFF	Nucleosome 3 of the 4x197 nucleosome array containing H1 Descriptor: DNA (167-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... Authors: Dombrowski, M, Cramer, P. Deposit date: 2021-08-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory. Nat.Struct.Mol.Biol., 29, 2022
7PFA	Trinucleosome of the 4x197 nucleosome array containing H1 Descriptor: DNA (561-MER), Histone H1.4, Histone H2A type 1-B/E, ... Authors: Dombrowski, M, Cramer, P. Deposit date: 2021-08-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (9.7 Å) Cite: Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory. Nat.Struct.Mol.Biol., 29, 2022
7PEU	Trinucleosome of the 4x177 nucleosome array containing H1 Descriptor: DNA (522-MER), Histone H1.4, Histone H2A type 1-B/E, ... Authors: Dombrowski, M, Cramer, P. Deposit date: 2021-08-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (7.2 Å) Cite: Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory. Nat.Struct.Mol.Biol., 29, 2022
7PFD	Nucleosome 1 of the 4x197 nucleosome array containing H1 Descriptor: DNA (172-MER), Histone H1.4, Histone H2A type 1-B/E, ... Authors: Dombrowski, M, Cramer, P. Deposit date: 2021-08-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory. Nat.Struct.Mol.Biol., 29, 2022
7PFE	Nucleosome 2 of the 4x197 nucleosome array containing H1 Descriptor: DNA (177-MER), Histone H1.4, Histone H2A type 1-B/E, ... Authors: Dombrowski, M, Cramer, P. Deposit date: 2021-08-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory. Nat.Struct.Mol.Biol., 29, 2022
7PFT	Trinucleosome of the 4x207 nucleosome array containing H1 Descriptor: DNA (591-MER), Histone H1.4, Histone H2A type 1-B/E, ... Authors: Dombrowski, M, Cramer, P. Deposit date: 2021-08-12 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (9.8 Å) Cite: Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory. Nat.Struct.Mol.Biol., 29, 2022
7PF0	Trinucleosome of the 4x177 nucleosome array containing H1 Descriptor: DNA (563-MER), Histone H1.4, Histone H2A type 1-B/E, ... Authors: Dombrowski, M, Cramer, P. Deposit date: 2021-08-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (11 Å) Cite: Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory. Nat.Struct.Mol.Biol., 29, 2022
7PFV	Nucleosome 1 of the 4x207 nucleosome array containing H1 Descriptor: DNA (177-MER), Histone H1.4, Histone H2A type 1-B/E, ... Authors: Dombrowski, M, Cramer, P. Deposit date: 2021-08-12 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory. Nat.Struct.Mol.Biol., 29, 2022
7PFW	Nucleosome 2 of the 4x207 nucleosome array containing H1 Descriptor: DNA (167-MER), Histone H1.4, Histone H2A type 1-B/E, ... Authors: Dombrowski, M, Cramer, P. Deposit date: 2021-08-12 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (5.2 Å) Cite: Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory. Nat.Struct.Mol.Biol., 29, 2022
3DRC	INVESTIGATION OF THE FUNCTIONAL ROLE OF TRYPTOPHAN-22 IN ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE BY SITE-DIRECTED MUTAGENESIS Descriptor: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ... Authors: Oatley, S.J, Kraut, J. Deposit date: 1992-09-22 Release date: 1994-01-31 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Investigation of the functional role of tryptophan-22 in Escherichia coli dihydrofolate reductase by site-directed mutagenesis. Biochemistry, 30, 1991
2K9K	Molecular characterization of the tonb2 protein from vibrio anguillarum Descriptor: TonB2 Authors: Lopez, C.S, Peacock, R.S, Crosa, J.H, Vogel, H.J. Deposit date: 2008-10-15 Release date: 2008-11-18 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Molecular characterization of the TonB2 protein from the fish pathogen Vibrio anguillarum. Biochem.J., 418, 2009
7QYV	BAZ2A bromodomain in complex with acetylpyrrole derivative compound 109 Descriptor: (2~{R})-1-[4-(4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrol-2-yl)-1,3-thiazol-2-yl]-~{N}-(4-oxidanylbutyl)piperazine-2-carboxamide, Bromodomain adjacent to zinc finger domain protein 2A, MAGNESIUM ION Authors: Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. Deposit date: 2022-01-29 Release date: 2022-09-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7QYW	BAZ2A bromodomain in complex with acetylpyrrole derivative compound 111 Descriptor: (2~{R})-1-[4-(4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrol-2-yl)-1,3-thiazol-2-yl]-~{N}-[3,3,3-tris(fluoranyl)propyl]piperazine-2-carboxamide, Bromodomain adjacent to zinc finger domain protein 2A, MAGNESIUM ION Authors: Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. Deposit date: 2022-01-29 Release date: 2022-09-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7QYT	BAZ2A bromodomain in complex with acetylpyrrole derivative compound 80 Descriptor: 3-methyl-1-(2-piperazin-1-yl-1,3-thiazol-4-yl)-2,5,6,7-tetrahydroisoindol-4-one, Bromodomain adjacent to zinc finger domain protein 2A Authors: Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. Deposit date: 2022-01-29 Release date: 2022-09-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7QYU	BAZ2A bromodomain in complex with acetylpyrrole derivative compound 88 Descriptor: 2-[4-[[4-[4-(4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrol-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]methyl]-1,2,3-triazol-1-yl]ethanamide, Bromodomain adjacent to zinc finger domain protein 2A Authors: Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. Deposit date: 2022-01-29 Release date: 2022-09-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7QZB	BAZ2A bromodomain in complex with acetylpyrrole derivative compound 98 Descriptor: 1,2-ETHANEDIOL, 3-methyl-1-[2-[4-[(4-methyl-1~{H}-pyrazol-3-yl)methyl]piperazin-1-yl]-1,3-thiazol-4-yl]-2,5,6,7-tetrahydroisoindol-4-one, Bromodomain adjacent to zinc finger domain protein 2A Authors: Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. Deposit date: 2022-01-31 Release date: 2022-09-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.151 Å) Cite: Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7QVU	BAZ2A bromodomain in complex with acetylpyrrole derivative fragment 25 Descriptor: 2-[4-(4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrol-2-yl)-1,3-thiazol-2-yl]guanidine, Bromodomain adjacent to zinc finger domain protein 2A, MAGNESIUM ION Authors: Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. Deposit date: 2022-01-23 Release date: 2022-09-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7QVV	BAZ2A bromodomain in complex with pyridone derivative fragment 36 Descriptor: 5-(4-azanylpiperidin-1-yl)carbonyl-1~{H}-pyridin-2-one, Bromodomain adjacent to zinc finger domain protein 2A Authors: Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. Deposit date: 2022-01-23 Release date: 2022-09-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.601 Å) Cite: Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7QWF	BAZ2A bromodomain in complex with acetylpyrrole derivative compound 45 Descriptor: 1,2-ETHANEDIOL, 1-[4-ethyl-2-methyl-5-[2-[2-(methylamino)ethyl]-1,3-thiazol-4-yl]-1~{H}-pyrrol-3-yl]ethanone, Bromodomain adjacent to zinc finger domain protein 2A, ... Authors: Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. Deposit date: 2022-01-25 Release date: 2022-09-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7QX2	BAZ2A bromodomain in complex with acetylpyrrole derivative compound 63 Descriptor: 1-[5-[2-[(4-azanylpiperidin-1-yl)methyl]-1,3-thiazol-4-yl]-4-ethyl-2-methyl-1~{H}-pyrrol-3-yl]ethanone, Bromodomain adjacent to zinc finger domain protein 2A Authors: Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. Deposit date: 2022-01-26 Release date: 2022-09-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.428 Å) Cite: Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7QWY	BAZ2A bromodomain in complex with acetylpyrrole derivative compound 61 Descriptor: 1-[4-ethyl-2-methyl-5-[2-(piperazin-1-ylmethyl)-1,3-thiazol-4-yl]-1~{H}-pyrrol-3-yl]ethanone, Bromodomain adjacent to zinc finger domain protein 2A Authors: Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. Deposit date: 2022-01-26 Release date: 2022-09-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.443 Å) Cite: Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7QX9	BAZ2A bromodomain in complex with acetylpyrrole derivative compound 65 Descriptor: 3-[[4-(4-ethanoyl-3,5-dimethyl-1~{H}-pyrrol-2-yl)-1,3-thiazol-2-yl]methyl]imidazolidine-2,4-dione, Bromodomain adjacent to zinc finger domain protein 2A Authors: Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. Deposit date: 2022-01-26 Release date: 2022-09-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7QZ4	BAZ2A bromodomain in complex with acetylpyrrole derivative compound 87 Descriptor: 1,2-ETHANEDIOL, 1-[4-ethyl-5-[2-[4-[(1-ethylpiperidin-4-yl)methyl]piperazin-1-yl]-1,3-thiazol-4-yl]-2-methyl-1~{H}-pyrrol-3-yl]ethanone, Bromodomain adjacent to zinc finger domain protein 2A Authors: Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. Deposit date: 2022-01-30 Release date: 2022-09-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7QZC	BAZ2A bromodomain in complex with acetylpyrrole derivative compound 104 Descriptor: (2R)-1-[4-(4-ethanoyl-3-ethyl-5-methyl-1H-pyrrol-2-yl)-1,3-thiazol-2-yl]-N-[2-(1,2-oxazol-5-yl)ethyl]piperazine-2-carboxamide, Bromodomain adjacent to zinc finger domain protein 2A, MAGNESIUM ION Authors: Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. Deposit date: 2022-01-31 Release date: 2022-09-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7QWU	BAZ2A bromodomain in complex with acetylpyrrole derivative compound 44 Descriptor: 1,2-ETHANEDIOL, 1-[5-[2-(3-azanylpropyl)-1,3-thiazol-4-yl]-4-ethyl-2-methyl-1~{H}-pyrrol-3-yl]ethanone, Bromodomain adjacent to zinc finger domain protein 2A Authors: Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. Deposit date: 2022-01-25 Release date: 2022-09-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022

<543544545546547548549550551552553554555556557558>