7MPJ
 
 | | Stm1 bound vacant 80S structure isolated from wild-type | | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | | Authors: | Rai, J, Zhao, Y, Li, H. | | Deposit date: | 2021-05-04 | | Release date: | 2022-05-11 | | Last modified: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations.
Structure, 30, 2022
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6HAP
 | | Adenylate kinase | | Descriptor: | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE | | Authors: | Kantaev, R, Inbal, R, Goldenzweig, A, Barak, Y, Dym, O, Peleg, Y, Albek, S, Fleishman, S.J, Haran, G. | | Deposit date: | 2018-08-08 | | Release date: | 2019-08-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Manipulating the Folding Landscape of a Multidomain Protein.
J.Phys.Chem.B, 122, 2018
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6YV7
 | | Mannosyltransferase PcManGT from Pyrobaculum calidifontis | | Descriptor: | Glycosyl transferase, family 2 | | Authors: | Divne, C, Rosaria, G. | | Deposit date: | 2020-04-28 | | Release date: | 2020-07-22 | | Last modified: | 2020-08-05 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A Transmembrane Crenarchaeal Mannosyltransferase Is Involved in N-Glycan Biosynthesis and Displays an Unexpected Minimal Cellulose-Synthase-like Fold.
J.Mol.Biol., 432, 2020
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8C01
 | | Enp1TAP_A population of yeast small ribosomal subunit precursors | | Descriptor: | 18S rRNA precursor, 20S-pre-rRNA D-site endonuclease NOB1, 40S ribosomal protein S0-A, ... | | Authors: | Milkereit, P, Poell, G. | | Deposit date: | 2022-12-15 | | Release date: | 2022-12-28 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Impact of the yeast S0/uS2-cluster ribosomal protein rpS21/eS21 on rRNA folding and the architecture of small ribosomal subunit precursors.
Plos One, 18, 2023
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7ZAH
 | | Cryo-EM structure of a Pyrococcus abyssi 30S bound to Met-initiator tRNA, mRNA, aIF1A and aIF5B | | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | Authors: | Coureux, P.D, Bourgeois, G, Mechulam, Y, Schmitt, E, Kazan, R. | | Deposit date: | 2022-03-22 | | Release date: | 2022-08-03 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Role of aIF5B in archaeal translation initiation.
Nucleic Acids Res., 50, 2022
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4PL0
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3RA4
 | | Structural studies of AAV8 capsid transitions associated with endosomal trafficking | | Descriptor: | Capsid protein, DNA (5'-D(*CP*A)-3') | | Authors: | Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M. | | Deposit date: | 2011-03-27 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking.
J.Virol., 85, 2011
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3RA2
 | | Structural studies of AAV8 capsid transitions associated with endosomal trafficking | | Descriptor: | Capsid protein | | Authors: | Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M. | | Deposit date: | 2011-03-26 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking.
J.Virol., 85, 2011
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3RA9
 | | Structural studies of AAV8 capsid transitions associated with endosomal trafficking | | Descriptor: | Capsid protein, DNA (5'-D(P*CP*A)-3') | | Authors: | Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M. | | Deposit date: | 2011-03-27 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking.
J.Virol., 85, 2011
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3RA8
 | | Structural studies of AAV8 capsid transitions associated with endosomal trafficking | | Descriptor: | ADENOSINE MONOPHOSPHATE, Capsid protein | | Authors: | Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M. | | Deposit date: | 2011-03-27 | | Release date: | 2011-09-21 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking.
J.Virol., 85, 2011
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1XAE
 | | Crystal structure of wild type yellow fluorescent protein zFP538 from Zoanthus | | Descriptor: | BETA-MERCAPTOETHANOL, fluorescent protein FP538 | | Authors: | Remington, S.J, Wachter, R.M, Yarbrough, D.K, Branchaud, B, Anderson, D.C, Kallio, K, Lukyanov, K.A. | | Deposit date: | 2004-08-25 | | Release date: | 2005-02-08 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | zFP538, a yellow-fluorescent protein from Zoanthus, contains a novel three-ring chromophore.
Biochemistry, 44, 2005
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3WLD
 | | Crystal structure of monomeric GCaMP6m | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Ding, J, Luo, A.F, Hu, L.Y, Wang, D.C, Shao, F. | | Deposit date: | 2013-11-08 | | Release date: | 2014-01-22 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis of the ultrasensitive calcium indicator GCaMP6.
Sci China Life Sci, 57, 2014
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8FEF
 | | Structure of Mce1 transporter from Mycobacterium smegmatis (Map0) | | Descriptor: | ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... | | Authors: | Chen, J, Bhabha, G, Ekiert, D.C. | | Deposit date: | 2022-12-06 | | Release date: | 2023-02-22 | | Last modified: | 2023-08-23 | | Method: | ELECTRON MICROSCOPY (2.71 Å) | | Cite: | Structure of an endogenous mycobacterial MCE lipid transporter.
Nature, 620, 2023
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8CF5
 | | Translocation intermediate 1 (TI-1) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | Authors: | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | | Deposit date: | 2023-02-02 | | Release date: | 2023-09-20 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.71 Å) | | Cite: | mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
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6SVQ
 | | Crystal structure of human GFAT-1 G461E after UDP-GlcNAc soaking | | Descriptor: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate-aminotransferase [isomerizing] 1 | | Authors: | Ruegenberg, S, Horn, M, Pichlo, C, Allmeroth, K, Baumann, U, Denzel, M.S. | | Deposit date: | 2019-09-18 | | Release date: | 2020-01-15 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.717 Å) | | Cite: | Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis.
Nat Commun, 11, 2020
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8CDL
 | | 80S S. cerevisiae ribosome with ligands in hybrid-2 pre-translocation (PRE-H2) complex | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | Authors: | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | | Deposit date: | 2023-01-31 | | Release date: | 2023-09-20 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.72 Å) | | Cite: | mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
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2Z6U
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8EVQ
 | | Hypopseudouridylated Ribosome bound with TSV IRES, eEF2, GDP, and sordarin, Structure I | | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | | Authors: | Zhao, Y, Rai, J, Li, H. | | Deposit date: | 2022-10-20 | | Release date: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (2.72 Å) | | Cite: | Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
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7ZC2
 | | Dipeptide and tripeptide Permease C (DtpC) | | Descriptor: | Amino acid/peptide transporter | | Authors: | Killer, M, Finocchio, G, Pardon, E, Steyaert, J, Loew, C. | | Deposit date: | 2022-03-25 | | Release date: | 2022-07-06 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (2.72 Å) | | Cite: | Cryo-EM Structure of an Atypical Proton-Coupled Peptide Transporter: Di- and Tripeptide Permease C.
Front Mol Biosci, 9, 2022
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3ZUV
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4JQ7
 | | Crystal structure of EGFR kinase domain in complex with compound 2a | | Descriptor: | (2S)-2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]-2-phenylethanol, Epidermal growth factor receptor | | Authors: | Peng, Y.H, Wu, J.S. | | Deposit date: | 2013-03-20 | | Release date: | 2013-06-19 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.73 Å) | | Cite: | Protein Kinase Inhibitor Design by Targeting the Asp-Phe-Gly (DFG) Motif: The Role of the DFG Motif in the Design of Epidermal Growth Factor Receptor Inhibitors
J.Med.Chem., 56, 2013
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7KVT
 | | Crystal structure of Squash RNA aptamer in complex with DFHBI-1T with iridium (III) ions | | Descriptor: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, IRIDIUM HEXAMMINE ION, MAGNESIUM ION, ... | | Authors: | Truong, L, Ferre-D'Amare, A.R. | | Deposit date: | 2020-11-28 | | Release date: | 2022-01-19 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.73 Å) | | Cite: | The fluorescent aptamer Squash extensively repurposes the adenine riboswitch fold.
Nat.Chem.Biol., 18, 2022
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7PWO
 | | Cryo-EM structure of Giardia lamblia ribosome at 2.75 A resolution | | Descriptor: | 40S ribosomal protein S21, 40S ribosomal protein S26, 40S ribosomal protein S30, ... | | Authors: | Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A. | | Deposit date: | 2021-10-07 | | Release date: | 2022-04-20 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia.
Nucleic Acids Res., 50, 2022
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8JQR
 | | Structure of human TRPV1 in complex with antagonist | | Descriptor: | 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile, CHOLESTEROL, Transient receptor potential cation channel subfamily V member 1,PreScission Site,Green fluorescent protein | | Authors: | Fan, J, Lei, X. | | Deposit date: | 2023-06-14 | | Release date: | 2024-08-14 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Structural basis of TRPV1 inhibition by SAF312 and cholesterol.
Nat Commun, 15, 2024
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2ZCJ
 | | Ternary structure of the Glu119Gln M.HhaI, C5-Cytosine DNA methyltransferase, with unmodified DNA and AdoHcy | | Descriptor: | DNA (5'-D(*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3'), DNA (5'-D(*DTP*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3'), Modification methylase HhaI, ... | | Authors: | Shieh, F.K, Reich, N.O. | | Deposit date: | 2007-11-09 | | Release date: | 2007-12-04 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | AdoMet-dependent Methyl-transfer: Glu(119) Is Essential for DNA C5-Cytosine Methyltransferase M.HhaI
J.Mol.Biol., 373, 2007
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