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2Y8I
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Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN-2 HEAVY CHAIN
Authors:Preller, M, Bauer, S, Adamek, N, Fujita-Becker, S, Fedorov, R, Geeves, M.A, Manstein, D.J.
Deposit date:2011-02-07
Release date:2011-07-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.132 Å)
Cite:Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V.
J.Biol.Chem., 286, 2011
2OS8
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Rigor-like structures of muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor
Descriptor: CALCIUM ION, MAGNESIUM ION, Myosin essential light chain, ...
Authors:Yang, Y, Gourinath, S, Cohen, C, Brown, J.H.
Deposit date:2007-02-05
Release date:2007-05-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Rigor-like Structures from Muscle Myosins Reveal Key Mechanical Elements in the Transduction Pathways of This Allosteric Motor.
Structure, 15, 2007
2OTG
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Rigor-like structures of muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ...
Authors:Yang, Y, Gourinath, S, Kovacs, M, Nyitray, L, Reutzel, R, Himmel, D.M, O'Neall-Hennessey, E, Reshetnikova, L, Szent-Gyorgyi, A.G, Brown, J.H, Cohen, C.
Deposit date:2007-02-08
Release date:2007-05-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Rigor-like Structures from Muscle Myosins Reveal Key Mechanical Elements in the Transduction Pathways of This Allosteric Motor.
Structure, 15, 2007
2XO8
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Crystal Structure of Myosin-2 in Complex with Tribromodichloropseudilin
Descriptor: 2,4-DICHLORO-6-(3,4,5-TRIBROMO-1H-PYRROL-2-YL)PHENOL, ADP METAVANADATE, MAGNESIUM ION, ...
Authors:Preller, M, Chinthalapudi, K, Martin, R, Knoelker, H.J, Manstein, D.J.
Deposit date:2010-08-10
Release date:2011-05-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibition of Myosin ATPase Activity by Halogenated Pseudilins: A Structure-Activity Study.
J.Med.Chem., 54, 2011
2X51
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M6 delta Insert1
Descriptor: CALCIUM ION, CALMODULIN, GLYCEROL, ...
Authors:Squires, G, Houdusse, A.
Deposit date:2010-02-04
Release date:2011-01-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Role of Insert-1 of Myosin Vi in Modulating Nucleotide Affinity.
J.Biol.Chem., 286, 2011
2Y0R
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Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2
Descriptor: MYOSIN-2 HEAVY CHAIN
Authors:Preller, M, Bauer, S, Adamek, N, Fujita-Becker, S, Fedorov, R, Geeves, M.A, Manstein, D.J.
Deposit date:2010-12-07
Release date:2011-07-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V.
J.Biol.Chem., 286, 2011
2X9H
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CRYSTAL STRUCTURE OF MYOSIN-2 MOTOR DOMAIN IN COMPLEX WITH ADP- METAVANADATE AND PENTACHLOROCARBAZOLE
Descriptor: 2,3,4,6,8-PENTACHLORO-9H-CARBAZOL-1-OL, ADP METAVANADATE, MAGNESIUM ION, ...
Authors:Selvadurai, J, Kirst, J, Knoelker, H.J, Manstein, D.J.
Deposit date:2010-03-19
Release date:2011-05-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Myosin-2 Motor Domain in Complex with Adp-Metavanadate and Pentachlorocarbazole
To be Published
2Y9E
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Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2
Descriptor: MYOSIN-2
Authors:Preller, M, Bauer, S, Adamek, N, Fujita-Becker, S, Fedorov, R, Geeves, M.A, Manstein, D.J.
Deposit date:2011-02-14
Release date:2011-07-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.397 Å)
Cite:Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V.
J.Biol.Chem., 286, 2011
2XEL
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Molecular Mechanism of Pentachloropseudilin Mediated Inhibition of Myosin Motor Activity
Descriptor: 2,4-DICHLORO-6-(3,4,5-TRICHLORO-1H-PYRROL-2YL)PHENOL, ADP METAVANADATE, MAGNESIUM ION, ...
Authors:Chinthalapudi, K, Taft, M.H, Martin, R, Hartmann, F.K, Heissler, S.M, Tsiavaliaris, G, Gutzeit, H.O, Knoelker, H.J, Coluccio, L.M, Fedorov, R, Manstein, D.J.
Deposit date:2010-05-16
Release date:2011-06-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism and Specificity of Pentachloropseudilin-Mediated Inhibition of Myosin Motor Activity.
J.Biol.Chem., 286, 2011
2VAS
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Myosin VI (MD-insert2-CaM, Delta-Insert1) Post-rigor state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, ...
Authors:Menetrey, J, Llinas, P, Cicolari, J, Squires, G, Liu, X, Li, A, Sweeney, H.L, Houdusse, A.
Deposit date:2007-09-04
Release date:2007-12-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Post-Rigor Structure of Myosin Vi and Implications for the Recovery Stroke.
Embo J., 27, 2008
2VB6
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Myosin VI (MD-insert2-CaM, Delta Insert1) Post-rigor state (crystal form 2)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, ...
Authors:Menetrey, J, Llinas, P, Cicolari, J, Squires, G, Liu, X, Li, A, Sweeney, H.L, Houdusse, A.
Deposit date:2007-09-06
Release date:2007-12-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Post-Rigor Structure of Myosin Vi and Implications for the Recovery Stroke.
Embo J., 27, 2008
2W4H
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BU of 2w4h by Molmil
Isometrically contracting insect asynchronous flight muscle quick frozen after a quick release step
Descriptor: MYOSIN HEAVY CHAIN, SKELETAL MUSCLE, ADULT, ...
Authors:Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A.
Deposit date:2008-11-25
Release date:2010-08-25
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
2W4A
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ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE
Descriptor: MYOSIN HEAVY CHAIN, SKELETAL MUSCLE, ADULT, ...
Authors:Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A.
Deposit date:2008-11-24
Release date:2010-04-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Plos One, 5, 2010
1W9K
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Dictyostelium discoideum Myosin II motor domain S456E with bound MgADP-BeFx
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Morris, C.A, Coureux, P.-D, Wells, A.L, Houdusse, A, Sweeney, H.L.
Deposit date:2004-10-13
Release date:2006-03-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure-Function Analysis of Myosin II Backdoor Mutants
To be Published
1W9J
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Myosin II Dictyostelium discoideum motor domain S456Y bound with MgADP-AlF4
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Morris, C.A, Coureux, P.-D, Wells, A.L, Houdusse, A, Sweeney, H.L.
Deposit date:2004-10-13
Release date:2006-03-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Function Analysis of Myosin II Backdoor Mutants
To be Published
1W7J
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Crystal Structure Of Myosin V Motor With Essential Light Chain + ADP-BeFx - Near Rigor
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Coureux, P.-D, Sweeney, H.L, Houdusse, A.
Deposit date:2004-09-03
Release date:2005-02-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three Myosin V Structures Delineate Essential Features of Chemo-Mechanical Transduction
Embo J., 23, 2004
1W9L
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BU of 1w9l by Molmil
Myosin II Dictyostelium discoideum motor domain S456E bound with MgADP-AlF4
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Morris, C.A, Coureux, P.-D, Wells, A.L, Houdusse, A, Sweeney, H.L.
Deposit date:2004-10-13
Release date:2006-03-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure-Function Analysis of Myosin II Backdoor Mutants
To be Published
1W7I
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BU of 1w7i by Molmil
Crystal Structure Of Myosin V Motor Without nucleotide soaked in 10 mM MgADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MYOSIN LIGHT CHAIN 1, SLOW-TWITCH MUSCLE A ISOFORM, ...
Authors:Coureux, P.-D, Sweeney, H.L, Houdusse, A.
Deposit date:2004-09-03
Release date:2005-02-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Three Myosin V Structures Delineate Essential Features of Chemo-Mechanical Transduction
Embo J., 23, 2004
1W9I
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BU of 1w9i by Molmil
Myosin II Dictyostelium discoideum motor domain S456Y bound with MgADP-BeFx
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Morris, C.A, Coureux, P.-D, Wells, A.L, Houdusse, A, Sweeney, H.L.
Deposit date:2004-10-13
Release date:2006-03-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure-Function Analysis of Myosin II Backdoor Mutants
To be Published
1VOM
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COMPLEX BETWEEN DICTYOSTELIUM MYOSIN AND MGADP AND VANADATE AT 1.9A RESOLUTION
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN, ...
Authors:Rayment, I, Smith, C.A.
Deposit date:1995-11-09
Release date:1996-12-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structure of the magnesium(II).ADP.vanadate complex of the Dictyostelium discoideum myosin motor domain to 1.9 A resolution.
Biochemistry, 35, 1996
3L9I
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Myosin VI nucleotide-free (mdinsert2) L310G mutant crystal structure
Descriptor: ACETATE ION, CALCIUM ION, Calmodulin, ...
Authors:Pylypenko, O, Song, L, Sweeney, L.H, Houdusse, A.
Deposit date:2010-01-05
Release date:2010-12-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Role of insert i of myosin VI in modulating nucleotide affinity
To be Published
3JAX
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BU of 3jax by Molmil
Heavy meromyosin from Schistosoma mansoni muscle thick filament by negative stain EM
Descriptor: myosin 2 heavy chain, myosin regulatory light chain, smooth muscle myosin essential light chain
Authors:Sulbaran, G, Alamo, L, Pinto, A, Marquez, G, Mendez, F, Padron, R, Craig, R.
Deposit date:2015-07-03
Release date:2015-10-07
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (23 Å)
Cite:An invertebrate smooth muscle with striated muscle myosin filaments.
Proc.Natl.Acad.Sci.USA, 112, 2015
3MNQ
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Crystal structure of myosin-2 motor domain in complex with ADP-metavanadate and resveratrol
Descriptor: 1,2-ETHANEDIOL, ADP METAVANADATE, MAGNESIUM ION, ...
Authors:Schneider, J, Taft, M, Backhaus, A, Baruch, P, Fedorov, R, Manstein, D.J.
Deposit date:2010-04-22
Release date:2011-04-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of resveratrol regulation of myosin activity.
To be Published
3JBH
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TWO HEAVY MEROMYOSIN INTERACTING-HEADS MOTIFS FLEXIBLE DOCKED INTO TARANTULA THICK FILAMENT 3D-MAP ALLOWS IN DEPTH STUDY OF INTRA- AND INTERMOLECULAR INTERACTIONS
Descriptor: MYOSIN 2 ESSENTIAL LIGHT CHAIN STRIATED MUSCLE, MYOSIN 2 HEAVY CHAIN STRIATED MUSCLE, MYOSIN 2 REGULATORY LIGHT CHAIN STRIATED MUSCLE
Authors:Alamo, L, Qi, D, Wriggers, W, Pinto, A, Zhu, J, Bilbao, A, Gillilan, R.E, Hu, S, Padron, R.
Deposit date:2015-09-01
Release date:2016-03-09
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis.
J. Mol. Biol., 428, 2016
3MKD
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Crystal structure of myosin-2 dictyostelium discoideum motor domain S456Y mutant in complex with adp-orthovanadate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin-2 heavy chain, ...
Authors:Kathmann, D, Diensthuber, R.P, Fedorov, R, Manstein, D.J, Tsiavaliaris, G.
Deposit date:2010-04-14
Release date:2011-04-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Switch-2 dependent modulation of the myosin power stroke
To be Published

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