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7QV3
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BU of 7qv3 by Molmil
Bacillus subtilis MutS2-collided disome complex (MutS2 conf.2; Leading 70S)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Filbeck, S, Pfeffer, S.
Deposit date:2022-01-19
Release date:2022-03-09
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (5.14 Å)
Cite:Bacterial ribosome collision sensing by a MutS DNA repair ATPase paralogue.
Nature, 603, 2022
7Q8W
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BU of 7q8w by Molmil
Crystal structure of TTBK1 in complex with VNG1.35 (compound 23)
Descriptor: 1,2-ETHANEDIOL, PHOSPHATE ION, Tau-tubulin kinase 1, ...
Authors:Chaikuad, A, Nozal, V, Martinez, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2021-11-11
Release date:2022-03-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.
J.Med.Chem., 65, 2022
7QV1
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BU of 7qv1 by Molmil
Bacillus subtilis collided disome (Leading 70S)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Filbeck, S, Pfeffer, S.
Deposit date:2022-01-19
Release date:2022-03-09
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Bacterial ribosome collision sensing by a MutS DNA repair ATPase paralogue.
Nature, 603, 2022
7QH4
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BU of 7qh4 by Molmil
Structure of the B. subtilis disome - collided 70S ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Kratzat, H, Buschauer, R, Berninghausen, O, Beckmann, R.
Deposit date:2021-12-10
Release date:2022-03-16
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (5.45 Å)
Cite:Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria.
Nature, 603, 2022
7QV2
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BU of 7qv2 by Molmil
Bacillus subtilis collided disome (Collided 70S)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Filbeck, S, Pfeffer, S.
Deposit date:2022-01-19
Release date:2022-03-09
Last modified:2022-04-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Bacterial ribosome collision sensing by a MutS DNA repair ATPase paralogue.
Nature, 603, 2022
7QGU
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BU of 7qgu by Molmil
Structure of the B. subtilis disome - stalled 70S ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Kratzat, H, Buschauer, R, Berninghausen, O, Beckmann, R.
Deposit date:2021-12-10
Release date:2022-03-16
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (4.75 Å)
Cite:Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria.
Nature, 603, 2022
8R55
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BU of 8r55 by Molmil
Bacillus subtilis MutS2-collided disome complex (collided 70S)
Descriptor: 16S rRNA (1533-MER), 23S RNA (2887-MER), 30S ribosomal protein S10, ...
Authors:Park, E, Mackens-Kiani, T, Berhane, R, Esser, H, Erdenebat, C, Burroughs, A.M, Berninghausen, O, Aravind, L, Beckmann, R, Green, R, Buskirk, A.R.
Deposit date:2023-11-16
Release date:2024-01-17
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage.
Embo J., 43, 2024
7ZHN
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BU of 7zhn by Molmil
Crystal structure of TTBK1 in complex with AMG28
Descriptor: 1,2-ETHANEDIOL, 4-(2-amino-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-11-yl)-2-methylbut-3-yn-2-ol, PHOSPHATE ION, ...
Authors:Chaikuad, A, Axtman, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2022-04-06
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis.
Sci Rep, 13, 2023
7ZHQ
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BU of 7zhq by Molmil
Crystal structure of TTBK1 in complex with compound 10 (7-009)
Descriptor: (3~{S})-1-(4-azanyl-3,5,12-triazatetracyclo[9.7.0.0^{2,7}.0^{13,18}]octadeca-1(11),2,4,6,13(18),14,16-heptaen-16-yl)-3-methyl-pent-1-yn-3-ol, 1,2-ETHANEDIOL, PHOSPHATE ION, ...
Authors:Chaikuad, A, Axtman, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2022-04-06
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis.
Sci Rep, 13, 2023
7ZHO
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BU of 7zho by Molmil
Crystal structure of TTBK1 in complex with compound 3 (7-001)
Descriptor: 1,2-ETHANEDIOL, 4-[3-(2-azanylpyrimidin-4-yl)-1~{H}-indol-5-yl]-2-methyl-but-3-yn-2-ol, PHOSPHATE ION, ...
Authors:Chaikuad, A, Axtman, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2022-04-06
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis.
Sci Rep, 13, 2023
7ZHP
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BU of 7zhp by Molmil
Crystal structure of TTBK1 in complex with compound 9 (7-005)
Descriptor: 1,2-ETHANEDIOL, 1-(4-azanyl-3,5,12-triazatetracyclo[9.7.0.0^{2,7}.0^{13,18}]octadeca-1(11),2,4,6,13(18),14,16-heptaen-16-yl)-3-ethyl-pent-1-yn-3-ol, PHOSPHATE ION, ...
Authors:Chaikuad, A, Axtman, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2022-04-06
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis.
Sci Rep, 13, 2023
8QCQ
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BU of 8qcq by Molmil
B. subtilis ApdA-stalled ribosomal complex
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Morici, M, Wilson, D.N.
Deposit date:2023-08-28
Release date:2024-03-20
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity.
Nat Commun, 15, 2024
1YXC
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BU of 1yxc by Molmil
Structure of E. coli dihydrodipicolinate synthase to 1.9 A
Descriptor: CHLORIDE ION, POTASSIUM ION, dihydrodipicolinate synthase
Authors:Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A.
Deposit date:2005-02-20
Release date:2005-08-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance.
Acta Crystallogr.,Sect.D, 61, 2005
2ATS
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BU of 2ats by Molmil
Dihydrodipicolinate synthase co-crystallised with (S)-lysine
Descriptor: CHLORIDE ION, D-LYSINE, POTASSIUM ION, ...
Authors:Devenish, S.R.A, Dobson, R.C.J, Jameson, G.B, Gerrard, J.A.
Deposit date:2005-08-26
Release date:2006-09-19
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The co-crystallisation of (S)-lysine-bound dihydrodipicolinate synthase from E. coli indicates that domain movements are not responsible for (S)-lysine inhibition
To be published
3J9W
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BU of 3j9w by Molmil
Cryo-EM structure of the Bacillus subtilis MifM-stalled ribosome complex
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein bS16, ...
Authors:Sohmen, D, Chiba, S, Shimokawa-Chiba, N, Innis, C.A, Berninghausen, O, Beckmann, R, Ito, K, Wilson, D.N.
Deposit date:2015-03-16
Release date:2015-04-29
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the Bacillus subtilis 70S ribosome reveals the basis for species-specific stalling.
Nat Commun, 6, 2015
2A6L
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BU of 2a6l by Molmil
Dihydrodipicolinate synthase (E. coli)- mutant R138H
Descriptor: Dihydrodipicolinate synthase, POTASSIUM ION
Authors:Dobson, R.C, Devenish, S.R, Turner, L.A, Clifford, V.R, Pearce, F.G, Jameson, G.B, Gerrard, J.A.
Deposit date:2005-07-03
Release date:2005-10-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase.
Biochemistry, 44, 2005
3J2Q
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BU of 3j2q by Molmil
Model of membrane-bound factor VIII organized in 2D crystals
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Stoilova-Mcphie, S, Lynch, G.C, Ludtke, S, Pettitt, B.M.
Deposit date:2012-12-11
Release date:2013-09-11
Last modified:2020-07-29
Method:ELECTRON CRYSTALLOGRAPHY (15 Å)
Cite:Domain organization of membrane-bound factor VIII.
Biopolymers, 99, 2013
2YSM
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BU of 2ysm by Molmil
Solution structure of the second and third PHD domain from Histone-lysine N-methyltransferase 2C (KMT2C/MLL3)
Descriptor: Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog, ZINC ION
Authors:Qin, X.R, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-03
Release date:2007-10-09
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the first and second PHD domain from Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog
To be Published
8BW4
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BU of 8bw4 by Molmil
PanDDA analysis -- Crystal Structure of PHIP in complex with Z198194396 synthetic derivative
Descriptor: (2R)-4-(3-fluoranylthiophen-2-yl)carbonyl-N-(4-methoxyphenyl)-2-methyl-piperazine-1-carboxamide, PH-interacting protein
Authors:Grosjean, H, Aimon, A, Hassell-Hart, S, Bradshaw, W.J, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Biggin, P.C, Spencer, J, von Delft, F.
Deposit date:2022-12-06
Release date:2022-12-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:PanDDA analysis -- Crystal Structure of PHIP in complex with Z198194396 synthetic derivative
To Be Published
8BW3
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BU of 8bw3 by Molmil
PanDDA analysis -- Crystal Structure of PHIP in complex with Z198194396 synthetic derivative
Descriptor: (2S)-N-(cyclopropylmethyl)-2-methyl-4-(1-methyl-1H-pyrrole-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein
Authors:Grosjean, H, Aimon, A, Hassell-Hart, S, Bradshaw, W.J, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Biggin, P.C, Spencer, J, von Delft, F.
Deposit date:2022-12-06
Release date:2022-12-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:PanDDA analysis -- Crystal Structure of PHIP in complex with Z198194396 synthetic derivative
To Be Published
8BW2
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BU of 8bw2 by Molmil
PanDDA analysis -- Crystal Structure of PHIP in complex with Z198194396 synthetic derivative
Descriptor: (2R)-N-(2-methoxyethyl)-2-methyl-4-thiophen-2-ylcarbonyl-piperazine-1-carboxamide, PH-interacting protein
Authors:Grosjean, H, Aimon, A, Hassell-Hart, S, Bradshaw, W.J, Krojer, T, Talon, R, Douangamath, A, Koekemoer, L, Biggin, P.C, Spencer, J, von Delft, F.
Deposit date:2022-12-06
Release date:2022-12-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:PanDDA analysis -- Crystal Structure of PHIP in complex with Z198194396 synthetic derivative
To Be Published
8BUU
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BU of 8buu by Molmil
ARE-ABCF VmlR2 bound to a 70S ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2022-11-30
Release date:2023-04-05
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Genome-encoded ABCF factors implicated in intrinsic antibiotic resistance in Gram-positive bacteria: VmlR2, Ard1 and CplR.
Nucleic Acids Res., 51, 2023
8CED
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BU of 8ced by Molmil
Rnase R bound to a 30S degradation intermediate (State I - head-turning)
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N.
Deposit date:2023-02-01
Release date:2023-12-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.15 Å)
Cite:Structural basis of ribosomal 30S subunit degradation by RNase R.
Nature, 626, 2024
8CEE
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BU of 8cee by Molmil
Rnase R bound to a 30S degradation intermediate (State I - head-turning)
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N.
Deposit date:2023-02-01
Release date:2023-12-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of ribosomal 30S subunit degradation by RNase R.
Nature, 626, 2024
8CDU
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BU of 8cdu by Molmil
Rnase R bound to a 30S degradation intermediate (main state)
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N.
Deposit date:2023-02-01
Release date:2023-12-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of ribosomal 30S subunit degradation by RNase R.
Nature, 626, 2024

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PDB entries from 2024-06-26

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