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1C1D
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L-PHENYLALANINE DEHYDROGENASE STRUCTURE IN TERNARY COMPLEX WITH NADH AND L-PHENYLALANINE
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ISOPROPYL ALCOHOL, L-PHENYLALANINE DEHYDROGENASE, ...
Authors:Vanhooke, J.L, Thoden, J.B.
Deposit date:1999-07-21
Release date:2000-08-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Rhodococcus L-phenylalanine dehydrogenase: kinetics, mechanism, and structural basis for catalytic specificity.
Biochemistry, 39, 2000
6XJX
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MCU holocomplex in Low-calcium blocking state
Descriptor: Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ...
Authors:Wang, Y, Jiang, Y.
Deposit date:2020-06-24
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural insights into the Ca 2+ -dependent gating of the human mitochondrial calcium uniporter.
Elife, 9, 2020
6XE0
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Cryo-EM structure of NusG-CTD bound to 70S ribosome (30S: NusG-CTD fragment)
Descriptor: 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Washburn, R, Zuber, P, Sun, M, Hashem, Y, Shen, B, Li, W, Harvey, S, Acosta-Reyes, F.J, Knauer, S.H, Frank, J, Gottesman, M.E.
Deposit date:2020-06-11
Release date:2020-07-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Escherichia coli NusG Links the Lead Ribosome with the Transcription Elongation Complex.
Iscience, 23, 2020
1C30
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CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ...
Authors:Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M.
Deposit date:1999-07-24
Release date:1999-12-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Biochemistry, 38, 1999
1C3O
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CRYSTAL STRUCTURE OF THE CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTANT C269S WITH BOUND GLUTAMINE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ...
Authors:Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M.
Deposit date:1999-07-28
Release date:1999-12-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Biochemistry, 38, 1999
1JAJ
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Solution Structure of DNA Polymerase X from the African Swine Fever Virus
Descriptor: DNA POLYMERASE BETA-LIKE PROTEIN
Authors:Maciejewski, M.W, Shin, R, Pan, B, Mullen, G.P.
Deposit date:2001-05-30
Release date:2001-10-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of a viral DNA repair polymerase.
Nat.Struct.Biol., 8, 2001
2K45
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BU of 2k45 by Molmil
C2A domain of synaptototagmin I solution structure in the FGF-1-C2A binary complex: key component in the fibroblast growthfactor non-classical pathway
Descriptor: Synaptotagmin-1
Authors:Mohan, S.K, Yu, C.
Deposit date:2008-05-28
Release date:2009-06-02
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:FGF-1-C2A binary complex structure: key component in the acidic fibroblast growth factor release
To be Published
7F0J
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CryoEM structure of human Kv4.2
Descriptor: Potassium voltage-gated channel subfamily D member 2, ZINC ION
Authors:Kise, Y, Nureki, O.
Deposit date:2021-06-04
Release date:2021-10-13
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of gating modulation of Kv4 channel complexes.
Nature, 599, 2021
7F3F
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CryoEM structure of human Kv4.2-KChIP1 complex
Descriptor: Isoform 2 of Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 2
Authors:Kise, Y, Nureki, O.
Deposit date:2021-06-16
Release date:2021-10-13
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of gating modulation of Kv4 channel complexes.
Nature, 599, 2021
2JF0
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Mus musculus acetylcholinesterase in complex with tabun and Ortho-7
Descriptor: 1,7-HEPTYLENE-BIS-N,N'-SYN-2-PYRIDINIUMALDOXIME, ACETYLCHOLINESTERASE, HEXAETHYLENE GLYCOL
Authors:Ekstrom, F, Astot, C, Pang, Y.P.
Deposit date:2007-01-25
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Novel Nerve-Agent Antidote Design Based on Crystallographic and Mass Spectrometric Analyses of Tabun-Conjugated Acetylcholinesterase in Complex with Antidotes.
Clin.Pharmacol.Ther., 82, 2007
2JGE
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Crystal structure of mouse acetylcholinesterase inhibited by non-aged methamidophos
Descriptor: ACETYLCHOLINESTERASE, HEXAETHYLENE GLYCOL, TRIETHYLENE GLYCOL
Authors:Hornberg, A, Tunemalm, A.-K, Ekstrom, F.
Deposit date:2007-02-13
Release date:2007-04-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of Acetylcholinesterase in Complex with Organophosphorus Compounds Suggest that the Acyl Pocket Modulates the Aging Reaction by Precluding the Formation of the Trigonal Bipyramidal Transition State.
Biochemistry, 46, 2007
2JEY
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Mus musculus acetylcholinesterase in complex with HLo-7
Descriptor: 1-[({2,4-BIS[(E)-(HYDROXYIMINO)METHYL]PYRIDINIUM-1-YL}METHOXY)METHYL]-4-CARBAMOYLPYRIDINIUM, ACETYLCHOLINESTERASE, HEXAETHYLENE GLYCOL
Authors:Ekstrom, F, Astot, C, Pang, Y.P.
Deposit date:2007-01-25
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Novel Nerve-Agent Antidote Design Based on Crystallographic and Mass Spectrometric Analyses of Tabun-Conjugated Acetylcholinesterase in Complex with Antidotes.
Clin.Pharmacol.Ther., 82, 2007
2JEZ
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Mus musculus acetylcholinesterase in complex with tabun and HLo-7
Descriptor: 1-[({2,4-BIS[(E)-(HYDROXYIMINO)METHYL]PYRIDINIUM-1-YL}METHOXY)METHYL]-4-CARBAMOYLPYRIDINIUM, ACETYLCHOLINESTERASE, HEXAETHYLENE GLYCOL
Authors:Ekstrom, F, Astot, C, Pang, Y.P.
Deposit date:2007-01-25
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Novel Nerve-Agent Antidote Design Based on Crystallographic and Mass Spectrometric Analyses of Tabun-Conjugated Acetylcholinesterase in Complex with Antidotes.
Clin.Pharmacol.Ther., 82, 2007
2NCT
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NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in the presence of hexafluoroisopropanol
Descriptor: Envelope glycoprotein gp41
Authors:Jimenez, M, Nieva, J.L, Rujas, E, Partida-Hanon, A, Bruix, M.
Deposit date:2016-04-14
Release date:2017-02-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface.
Sci Rep, 6, 2016
1EBF
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HOMOSERINE DEHYDROGENASE FROM S. CEREVISIAE COMPLEX WITH NAD+
Descriptor: HOMOSERINE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION
Authors:DeLaBarre, B, Thompson, P.R, Wright, G.D, Berghuis, A.M.
Deposit date:2000-01-24
Release date:2000-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases.
Nat.Struct.Biol., 7, 2000
2KIV
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AIDA-1 SAM domain tandem
Descriptor: Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Authors:Donaldson, L.W, Kurabi, A.
Deposit date:2009-05-12
Release date:2009-08-25
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:A nuclear localization signal at the SAM-SAM domain interface of AIDA-1 suggests a requirement for domain uncoupling prior to nuclear import.
J.Mol.Biol., 392, 2009
1E59
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E.coli cofactor-dependent phosphoglycerate mutase complexed with vanadate
Descriptor: CHLORIDE ION, PHOSPHOGLYCERATE MUTASE, TETRAMETAVANADATE
Authors:Bond, C.S, Hunter, W.N.
Deposit date:2000-07-19
Release date:2002-02-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Mechanistic Implications for Escherichia Coli Cofactor-Dependent Phosphoglycerate Mutase Based on the High-Resolution Crystal Structure of a Vanadate Complex.
J.Mol.Biol., 316, 2002
1E74
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NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT R11E
Descriptor: ALPHA-CONOTOXIN IM1(R11E)
Authors:Rogers, J.P, Luginbuhl, P, Pemberton, K, Harty, P, Wemmer, D.E, Stevens, R.C.
Deposit date:2000-08-24
Release date:2000-12-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304, 2000
1E76
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NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT D5N
Descriptor: ALPHA-CONOTOXIN IM1(D5N)
Authors:Rogers, J.P, Luginbuhl, P, Pemberton, K, Harty, P, Wemmer, D.E, Stevens, R.C.
Deposit date:2000-08-24
Release date:2000-12-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304, 2000
1E75
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NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT R7L
Descriptor: ALPHA-CONOTOXIN IM1(R7L)
Authors:Rogers, J.P, Luginbuhl, P, Pemberton, K, Harty, P, Wemmer, D.E, Stevens, R.C.
Deposit date:2000-08-24
Release date:2000-12-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304, 2000
2LL4
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HADDOCK structure of TgMIC4-A5/lacto-N-biose complex, based on NOE-derived distance restraints
Descriptor: Micronemal protein 4, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Cowper, B, Matthews, S.
Deposit date:2011-10-26
Release date:2012-04-04
Last modified:2020-07-29
Method:SOLUTION NMR
Cite:Galactose Recognition by the Apicomplexan Parasite Toxoplasma gondii.
J.Biol.Chem., 287, 2012
2LK3
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U2/U6 Helix I
Descriptor: RNA (5'-R(*GP*GP*CP*UP*UP*AP*GP*AP*UP*CP*AP*GP*AP*AP*AP*UP*GP*AP*UP*CP*AP*GP*CP*C)-3')
Authors:Burke, J.E, Sashital, D.G, Zuo, X.E, Wang, Y, Butcher, S.E.
Deposit date:2011-10-03
Release date:2012-02-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the yeast U2/U6 snRNA complex.
Rna, 18, 2012
1E6J
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Crystal structure of HIV-1 capsid protein (p24) in complex with Fab13B5
Descriptor: CAPSID PROTEIN P24, IMMUNOGLOBULIN
Authors:Berthet-Colominas, C, Monaco, S, Novelli, A, Sibai, G, Mallet, F, Cusack, S.
Deposit date:2000-08-18
Release date:2000-11-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mutual Conformational Adaptations in Antigen and Antibody Upon Complex Formation between an Fab and HIV-1 Capsid Protein P24
Structure, 8, 2000
1E9N
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A second divalent metal ion in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1, and its implications for the catalytic mechanism
Descriptor: DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE, LEAD (II) ION
Authors:Beernink, P.T, Segelke, B.W, Rupp, B.
Deposit date:2000-10-24
Release date:2001-02-16
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism
J.Mol.Biol., 307, 2001
1JPS
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Crystal structure of tissue factor in complex with humanized Fab D3h44
Descriptor: immunoglobulin Fab D3H44, heavy chain, light chain, ...
Authors:Faelber, K, Kirchhofer, D, Presta, L, Kelley, R.F, Muller, Y.A.
Deposit date:2001-08-03
Release date:2002-02-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites.
J.Mol.Biol., 313, 2001

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