2O1W
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1JWB
| Structure of the Covalent Acyl-Adenylate Form of the MoeB-MoaD Protein Complex | Descriptor: | ADENOSINE MONOPHOSPHATE, MOLYBDOPTERIN BIOSYNTHESIS MOEB PROTEIN, MOLYBDOPTERIN [MPT] CONVERTING FACTOR, ... | Authors: | Lake, M.W, Wuebbens, M.M, Rajagopalan, K.V, Schindelin, H. | Deposit date: | 2001-09-03 | Release date: | 2001-11-21 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex. Nature, 414, 2001
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1Z6D
| Ribonuclease A- IMP complex | Descriptor: | INOSINIC ACID, Ribonuclease pancreatic | Authors: | Hatzopoulos, G.N, Leonidas, D.D, Kardakaris, R, Kobe, J, Oikonomakos, N.G. | Deposit date: | 2005-03-22 | Release date: | 2005-08-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | The binding of IMP to Ribonuclease A Febs J., 272, 2005
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2HBK
| Structure of the yeast nuclear exosome component, Rrp6p, reveals an interplay between the active site and the HRDC domain; Protein in complex with Mn | Descriptor: | Exosome complex exonuclease RRP6, MANGANESE (II) ION | Authors: | Midtgaard, S.F, Assenholt, J, Jonstrup, A.T, Van, L.B, Jensen, T.H, Brodersen, D.E. | Deposit date: | 2006-06-14 | Release date: | 2006-07-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain. Proc.Natl.Acad.Sci.Usa, 103, 2006
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3EH9
| Crystal structure of death associated protein kinase complexed with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Death-associated protein kinase 1, SULFATE ION | Authors: | McNamara, L.K, Watterson, D.M, Brunzelle, J.S. | Deposit date: | 2008-09-11 | Release date: | 2009-04-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insight into nucleotide recognition by human death-associated protein kinase. Acta Crystallogr.,Sect.D, 65, 2009
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1LP8
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2HBJ
| Structure of the yeast nuclear exosome component, Rrp6p, reveals an interplay between the active site and the HRDC domain | Descriptor: | Exosome complex exonuclease RRP6 | Authors: | Midtgaard, S.F, Assenholt, J, Jonstrup, A.T, Van, L.B, Jensen, T.H, Brodersen, D.E. | Deposit date: | 2006-06-14 | Release date: | 2006-07-25 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1KZ8
| CRYSTAL STRUCTURE OF PORCINE FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH A NOVEL ALLOSTERIC-SITE INHIBITOR | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, FRUCTOSE-1,6-BISPHOSPHATASE, ... | Authors: | Wright, S.W, Carlo, A.A, Carty, M.D, Danley, D.E, Hageman, D.L, Karam, G.A, Levy, C.B, Mansour, M.N, Mathiowetz, A.M, McClure, L.D, Nestor, N.B, McPherson, R.K, Pandit, J, Pustilnik, L.R, Schulte, G.K, Soeller, W.C, Treadway, J.L, Wang, I.-K, Bauer, P.H. | Deposit date: | 2002-02-06 | Release date: | 2002-10-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | ANILINOQUINAZOLINE INHIBITORS OF FRUCTOSE 1,6-BISPHOSPHATASE BIND AT A NOVEL ALLOSTERIC SITE: SYNTHESIS, IN VITRO CHARACTERIZATION, AND X-RAY CRYSTALLOGRAPHY J.MED.CHEM., 45, 2002
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1LPD
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6UQF
| Human HCN1 channel in a hyperpolarized conformation | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, MERCURY (II) ION, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | Authors: | Lee, C.-H, MacKinnon, R. | Deposit date: | 2019-10-19 | Release date: | 2019-12-11 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Voltage Sensor Movements during Hyperpolarization in the HCN Channel. Cell, 179, 2019
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6UQG
| Human HCN1 channel Y289D mutant | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | Authors: | Lee, C.-H, MacKinnon, R. | Deposit date: | 2019-10-19 | Release date: | 2019-12-11 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Voltage Sensor Movements during Hyperpolarization in the HCN Channel. Cell, 179, 2019
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7COQ
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2CNQ
| Atomic resolution structure of SAICAR-synthase from Saccharomyces cerevisiae complexed with ADP, AICAR, succinate | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, ... | Authors: | Urusova, D.V, Antonyuk, S.V, Grebenko, A.I, Levdikov, V.M, Barynin, V.V, Popov, A.N, Lamzin, V.S, Melik-Adamyan, W.R. | Deposit date: | 2006-05-23 | Release date: | 2006-06-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Saicar Synthase: Substrate Recognition, Conformational Flexibility and Catalysis. To be Published
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7DQD
| Crystal structure of the AMP-PNP-bound mutant A(S23C)3B(N64C)3 complex from enterococcus hirae V-ATPase | Descriptor: | GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Maruyama, S, Suzuki, K, Mizutani, K, Imai, F.L, Ishizuka-Katsura, Y, Shirouzu, M, Murata, T. | Deposit date: | 2020-12-23 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.383 Å) | Cite: | The combination of high-speed AFM and X-ray crystallography reveals rotary catalysis To Be Published
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8BIT
| Crystal structure of acyl-CoA synthetase from Metallosphaera sedula in complex with Coenzyme A and acetyl-AMP | Descriptor: | 4-hydroxybutyrate--CoA ligase 1, COENZYME A, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] ethanoate | Authors: | Capra, N, Thunnissen, A.M.W.H, Janssen, D.B. | Deposit date: | 2022-11-02 | Release date: | 2023-11-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Adapting an acyl CoA ligase from Metallosphaera sedula for lactam formation by structure-guided protein engineering Front Catal, 4, 2024
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8WU4
| Cryo-EM structure of native H. thermoluteolus TH-1 GroEL | Descriptor: | Chaperonin GroEL | Authors: | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | Deposit date: | 2023-10-20 | Release date: | 2024-03-27 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural insights into thermophilic chaperonin complexes. Structure, 32, 2024
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8WUX
| Cryo-EM structure of H. thermophilus GroEL-GroES bullet complex | Descriptor: | Chaperonin GroEL, Co-chaperonin GroES, MAGNESIUM ION, ... | Authors: | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | Deposit date: | 2023-10-21 | Release date: | 2024-03-27 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural insights into thermophilic chaperonin complexes. Structure, 32, 2024
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8WUC
| Cryo-EM structure of H. thermoluteolus GroEL-GroES2 football complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | Authors: | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | Deposit date: | 2023-10-20 | Release date: | 2024-03-27 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structural insights into thermophilic chaperonin complexes. Structure, 32, 2024
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6MY3
| Solution structure of gomesin at 310K | Descriptor: | gomesin | Authors: | Chin, Y.K.-Y, Deplazes, E. | Deposit date: | 2018-11-01 | Release date: | 2019-11-06 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The unusual conformation of cross-strand disulfide bonds is critical to the stability of beta-hairpin peptides. Proteins, 88, 2020
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8UYI
| Structure of ADP-bound and phosphorylated Pediculus humanus (Ph) PINK1 dimer | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase Pink1, ... | Authors: | Gan, Z.Y, Kirk, N.S, Leis, A, Komander, D. | Deposit date: | 2023-11-13 | Release date: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Interaction of PINK1 with nucleotides and kinetin. Sci Adv, 10, 2024
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8UYF
| Structure of nucleotide-free Pediculus humanus (Ph) PINK1 dimer | Descriptor: | Serine/threonine-protein kinase Pink1, mitochondrial | Authors: | Gan, Z.Y, Kirk, N.S, Leis, A, Komander, D. | Deposit date: | 2023-11-13 | Release date: | 2024-01-31 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Interaction of PINK1 with nucleotides and kinetin. Sci Adv, 10, 2024
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1P8L
| New Crystal Structure of Chlorella Virus DNA Ligase-Adenylate | Descriptor: | ADENOSINE MONOPHOSPHATE, PBCV-1 DNA ligase | Authors: | Odell, M, Malinina, L, Teplova, M, Shuman, S. | Deposit date: | 2003-05-07 | Release date: | 2003-08-26 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Analysis of the DNA Joining Repertoire of Chlorella Virus DNA ligase and a New Crystal Structure of the Ligase-Adenylate Intermediate Nucleic Acids Res., 31, 2003
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4IMY
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2ATI
| Glycogen Phosphorylase Inhibitors | Descriptor: | Glycogen phosphorylase, liver form, N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA, ... | Authors: | Klabunde, T, Wendt, K.U, Kadereit, D, Brachvogel, V, Burger, H.J, Herling, A.W, Oikonomakos, N.G, Schmoll, D, Sarubbi, E, von Roedern, E, Schoenafinger, K, Defossa, E. | Deposit date: | 2005-08-25 | Release date: | 2006-08-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. J.Med.Chem., 48, 2005
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1Q9D
| Fructose-1,6-bisphosphatase Complexed with a New Allosteric Site Inhibitor (I-State) | Descriptor: | 3-(4-HYDROXYBENZYL)-2-[1-({[2-(4-HYDROXYPHENYL)ETHYL]AMINO}CARBONYL)BUTYL]-4-OXO-3,6,11,11A-TETRAHYDRO-4H-PYRAZINO[1,2-B]ISOQUINOLIN-2-IUM-1-OLATE, 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase, ... | Authors: | Honzatko, R.B, Choe, J.Y. | Deposit date: | 2003-08-25 | Release date: | 2003-12-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Inhibition of fructose-1,6-bisphosphatase by a new class of allosteric effectors J.Biol.Chem., 278, 2003
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