8XOV
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![BU of 8xov by Molmil](/molmil-images/mine/8xov) | The Crystal Structure of N-terminal kinase domain of human RSK-1 from Biortus. | Descriptor: | 1,2-ETHANEDIOL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-1 | Authors: | Wang, F, Cheng, W, Lv, Z, Meng, Q, Zhang, B. | Deposit date: | 2024-01-02 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The Crystal Structure of N-terminal kinase domain of human RSK-1 from Biortus. To Be Published
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8XOU
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![BU of 8xou by Molmil](/molmil-images/mine/8xou) | Prohead portal vertex of bacteriophage lambda | Descriptor: | Major capsid protein, Portal protein B | Authors: | Wang, J.W, Gu, Z.W. | Deposit date: | 2024-01-02 | Release date: | 2024-04-10 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (5.58 Å) | Cite: | Structural morphing in the viral portal vertex of bacteriophage lambda. J.Virol., 98, 2024
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8XOT
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![BU of 8xot by Molmil](/molmil-images/mine/8xot) | Prohead portal of bacteriophage lambda | Descriptor: | Portal protein B | Authors: | Wang, J.W, Gu, Z.W. | Deposit date: | 2024-01-02 | Release date: | 2024-04-10 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | Structural morphing in the viral portal vertex of bacteriophage lambda. J.Virol., 98, 2024
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8XOP
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![BU of 8xop by Molmil](/molmil-images/mine/8xop) | |
8XOO
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![BU of 8xoo by Molmil](/molmil-images/mine/8xoo) | |
8XON
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![BU of 8xon by Molmil](/molmil-images/mine/8xon) | |
8XOM
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![BU of 8xom by Molmil](/molmil-images/mine/8xom) | Cryo-EM structure of human ABCC4 in complex with ANP-bound in NBD1 and METHOTREXATE | Descriptor: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ... | Authors: | Zhang, P.F, Liu, Z. | Deposit date: | 2024-01-01 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport. Febs Lett., 2024
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8XOL
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![BU of 8xol by Molmil](/molmil-images/mine/8xol) | Cryo-EM structure of human ABCC4 with ANP bound in NBD1 | Descriptor: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ... | Authors: | Zhang, P.F, Liu, Z. | Deposit date: | 2024-01-01 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport. Febs Lett., 2024
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8XOJ
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![BU of 8xoj by Molmil](/molmil-images/mine/8xoj) | Cryo-EM structure of GPR30-Gq complex structure in the presence of G-1 | Descriptor: | G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, H, Xu, P, Xu, H.E. | Deposit date: | 2024-01-01 | Release date: | 2024-04-10 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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8XOI
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![BU of 8xoi by Molmil](/molmil-images/mine/8xoi) | Cryo-EM structure of GPR30-Gq complex structure in the presence of fulvestrant | Descriptor: | G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, H, Xu, P, Xu, H.E. | Deposit date: | 2024-01-01 | Release date: | 2024-04-10 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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8XOH
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![BU of 8xoh by Molmil](/molmil-images/mine/8xoh) | Cryo-EM structure of GPR30-Gq complex structure in the presence of E2 | Descriptor: | G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, H, Xu, P, Xu, H.E. | Deposit date: | 2024-01-01 | Release date: | 2024-04-10 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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8XOG
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![BU of 8xog by Molmil](/molmil-images/mine/8xog) | Cryo-EM structure of apo-GPR30-Gq complex structure | Descriptor: | G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, H, Xu, P, Xu, H.E. | Deposit date: | 2024-01-01 | Release date: | 2024-04-10 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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8XOF
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![BU of 8xof by Molmil](/molmil-images/mine/8xof) | Cryo-EM structure of Lys05 bound GPR30-Gq complex structure | Descriptor: | G protein subunit q, G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Liu, H, Xu, P, Xu, H.E. | Deposit date: | 2024-01-01 | Release date: | 2024-04-10 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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8XOB
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![BU of 8xob by Molmil](/molmil-images/mine/8xob) | VMAT2 protonated state | Descriptor: | Synaptic vesicular amine transporter,transporter B | Authors: | Jiang, D.H, Wu, D. | Deposit date: | 2023-12-31 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | VMAT2 protonated state To Be Published
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8XOA
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![BU of 8xoa by Molmil](/molmil-images/mine/8xoa) | VMAT2 complex with MPP+ | Descriptor: | 1-methyl-4-phenylpyridin-1-ium, Synaptic vesicular amine transporter,Synaptic vesicular amine transporter,transporterA | Authors: | Jiang, D.H, Wu, D. | Deposit date: | 2023-12-31 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | VMAT2 complex with MPP+ To Be Published
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8XO9
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![BU of 8xo9 by Molmil](/molmil-images/mine/8xo9) | |
8XNK
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![BU of 8xnk by Molmil](/molmil-images/mine/8xnk) | Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P) in complex with human ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | Authors: | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | Deposit date: | 2023-12-30 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86, EG.5, EG.5.1 and HV.1 sub-variants To Be Published
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8XNH
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![BU of 8xnh by Molmil](/molmil-images/mine/8xnh) | Nipah virus fusion glycoprotein in complex with a broadly neutralizing antibody 5C8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5C8-VH, 5C8-VL, ... | Authors: | Fan, P.F, Ren, Y, Yu, C.M, Chen, W. | Deposit date: | 2023-12-30 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Nipah virus fusion glycoprotein in complex with a broadly neutralizing antibody 1D6 To Be Published
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8XNG
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8XNF
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![BU of 8xnf by Molmil](/molmil-images/mine/8xnf) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P) in complex with human ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | Deposit date: | 2023-12-29 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86.1, EG.5, EG.5.1 and HV.1 sub-variants To Be Published
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8XN9
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![BU of 8xn9 by Molmil](/molmil-images/mine/8xn9) | Nipah virus fusion glycoprotein in complex with a broadly neutralizing antibody 1D6 | Descriptor: | 1D6 VH, 1D6 VL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Fan, P.F, Ren, Y, Yu, C.M, Chen, W. | Deposit date: | 2023-12-29 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (1.99 Å) | Cite: | Nipah virus fusion glycoprotein in complex with a broadly neutralizing antibody 1D6 To Be Published
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8XN8
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![BU of 8xn8 by Molmil](/molmil-images/mine/8xn8) | The Crystal Structure of SRC from Biortus. | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C. | Deposit date: | 2023-12-29 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Crystal Structure of SRC from Biortus. To Be Published
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8XN7
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![BU of 8xn7 by Molmil](/molmil-images/mine/8xn7) | Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with compound 9f | Descriptor: | 5-amino-2-((6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino)-8-(2-(trifluoromethyl)benzyl)pyrido[2,3-d]pyrimidin-7(8H)-one, Mitogen-activated protein kinase kinase kinase kinase 1 | Authors: | Huang, W.X, Liu, R, Ding, K. | Deposit date: | 2023-12-29 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Discovery of 5-aminopyrido[2,3-d]pyrimidin-7(8H)-one derivatives as new hematopoietic progenitor kinase 1 (HPK1) inhibitors. Eur.J.Med.Chem., 269, 2024
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8XN6
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![BU of 8xn6 by Molmil](/molmil-images/mine/8xn6) | The Crystal Structure of GSK3b from Biortus. | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Glycogen synthase kinase-3 beta, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Wu, B. | Deposit date: | 2023-12-29 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Crystal Structure of GSK3b from Biortus. To Be Published
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8XN5
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![BU of 8xn5 by Molmil](/molmil-images/mine/8xn5) | Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P) in complex with human ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | Authors: | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | Deposit date: | 2023-12-29 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86, EG.5, EG.5.1 and HV.1 sub-variants To Be Published
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