6VCR
| Crystal structure of E.coli RppH in complex with CTP | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, PYROPHOSPHATE, RNA pyrophosphohydrolase, ... | Authors: | Gao, A, Vasilyev, N, Kaushik, A, Duan, W, Serganov, A. | Deposit date: | 2019-12-21 | Release date: | 2020-02-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Principles of RNA and nucleotide discrimination by the RNA processing enzyme RppH. Nucleic Acids Res., 48, 2020
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4WT9
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8WI7
| Cryo- EM structure of Mycobacterium smegmatis 70S ribosome, bS1 and RafH. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Kumar, N, Sharma, S, Kaushal, P.S. | Deposit date: | 2023-09-24 | Release date: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
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8WHX
| Cryo- EM structure of Mycobacterium smegmatis 70S ribosome and RafH. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Kumar, N, Sharma, S, Kaushal, P.S. | Deposit date: | 2023-09-23 | Release date: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
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6ROL
| Structure of IMP2 KH34 domains | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Insulin-like growth factor 2 mRNA-binding protein 2, ... | Authors: | Bhaskar, V, Biswas, J, Singer, R.H, Chao, J.A. | Deposit date: | 2019-05-13 | Release date: | 2019-10-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structural basis for RNA selectivity by the IMP family of RNA-binding proteins. Nat Commun, 10, 2019
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3L28
| Crystal structure of Zaire Ebola VP35 interferon inhibitory domain K339A mutant | Descriptor: | CHLORIDE ION, Polymerase cofactor VP35, SODIUM ION, ... | Authors: | Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K. | Deposit date: | 2009-12-14 | Release date: | 2010-01-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35. Nat.Struct.Mol.Biol., 17, 2010
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6T0V
| Bat Influenza A polymerase elongation complex with incoming UTP analogue (complete polymerase) | Descriptor: | 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... | Authors: | Wandzik, J.M, Kouba, T, Cusack, S. | Deposit date: | 2019-10-03 | Release date: | 2020-04-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
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3L27
| Crystal structure of Zaire Ebola VP35 interferon inhibitory domain R312A mutant | Descriptor: | CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ... | Authors: | Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K. | Deposit date: | 2009-12-14 | Release date: | 2010-01-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35. Nat.Struct.Mol.Biol., 17, 2010
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8E4X
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8E0F
| Human Adenosine Deaminase Acting on dsRNA (ADAR2-RD) bound to dsRNA containing a G-G pair adjacent to the target site | Descriptor: | Double-stranded RNA-specific editase 1, INOSITOL HEXAKISPHOSPHATE, RNA (5-R(*GP*CP*UP*CP*GP*CP*GP*AP*UP*GP*CP*GP*(8AZ)P*GP*AP*GP*GP*GP*CP* UP*CP*UP*GP*AP*UP*AP*GP*CP*UP*AP*CP*G)-3), ... | Authors: | Wilcox, X.E, Fisher, A.J, Beal, P.A. | Deposit date: | 2022-08-09 | Release date: | 2022-10-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | ADAR activation by inducing a syn conformation at guanosine adjacent to an editing site. Nucleic Acids Res., 50, 2022
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3IY8
| Leishmania tarentolae Mitonchondrial Ribosome small subunit | Descriptor: | 30S ribosomal protein S11, 30S ribosomal protein S12, 30S ribosomal protein S15, ... | Authors: | Sharma, M.R, Booth, T.M, Simpson, L, Maslov, D.A, Agrawal, R.K. | Deposit date: | 2009-04-16 | Release date: | 2009-07-07 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (14.1 Å) | Cite: | Structure of a mitochondrial ribosome with minimal RNA Proc.Natl.Acad.Sci.USA, 106, 2009
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5XY3
| Large subunit of Trichomonas vaginalis ribosome | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | Deposit date: | 2017-07-06 | Release date: | 2017-08-30 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii Cell Res., 27, 2017
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6SZV
| Bat Influenza A polymerase elongation complex with incoming UTP analogue (core + endonuclease only) | Descriptor: | 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... | Authors: | Wandzik, J.M, Kouba, T, Cusack, S. | Deposit date: | 2019-10-02 | Release date: | 2020-04-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
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7NAF
| State E2 nucleolar 60S ribosomal biogenesis intermediate - Spb1-MTD local model | Descriptor: | 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | Authors: | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | Deposit date: | 2021-06-21 | Release date: | 2022-11-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
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5XXB
| Large subunit of Toxoplasma gondii ribosome | Descriptor: | 25S RNA, 5.8S RNA, 5S RNA, ... | Authors: | Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | Deposit date: | 2017-07-03 | Release date: | 2017-08-30 | Last modified: | 2017-10-18 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii Cell Res., 27, 2017
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4D2P
| Structure of MELK in complex with inhibitors | Descriptor: | 7-({4-[(3-hydroxy-5-methoxyphenyl)amino]benzoyl}amino)-1,2,3,4-tetrahydroisoquinolinium, MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE | Authors: | Johnson, C.N, Berdini, V, Beke, L, Bonnet, P, Brehmer, D, Coyle, J.E, Day, P.J, Frederickson, M, Freyne, E.J.E, Gilissen, R.A.H.J, Hamlett, C.C.F, Howard, S, Meerpoel, L, McMenamin, R, Patel, S, Rees, D.C, Sharff, A, Sommen, F, Wu, T, Linders, J.T.M. | Deposit date: | 2014-05-12 | Release date: | 2014-10-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase Acs Med.Chem.Lett., 6, 2015
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4CVQ
| CRYSTAL STRUCTURE OF AN AMINOTRANSFERASE FROM ESCHERICHIA COLI AT 2. 11 ANGSTROEM RESOLUTION | Descriptor: | ACETATE ION, GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA, GLYCEROL, ... | Authors: | Penya-Soler, E, Fernandez, F.J, Lopez-Estepa, M, Garces, F, Richardson, A.J, Rudd, K.E, Coll, M, Vega, M.C. | Deposit date: | 2014-03-28 | Release date: | 2014-07-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Structural analysis and mutant growth properties reveal distinctive enzymatic and cellular roles for the three major L-alanine transaminases of Escherichia coli. PLoS ONE, 9, 2014
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3LYF
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8FVY
| 40S subunit of the Giardia lamblia 80S ribosome | Descriptor: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S25, ... | Authors: | Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S. | Deposit date: | 2023-01-20 | Release date: | 2024-01-24 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function. Structure, 32, 2024
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8WI8
| Cryo- EM structure of Mycobacterium smegmatis 50S ribosomal subunit (body 1) of 70S ribosome, bS1 and RafH. | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Kumar, N, Sharma, S, Kaushal, P.S. | Deposit date: | 2023-09-24 | Release date: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
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5AFF
| Symportin 1 chaperones 5S RNP assembly during ribosome biogenesis by occupying an essential rRNA binding site | Descriptor: | RIBOSOMAL PROTEIN L11, RIBOSOMAL PROTEIN L5, SYMPORTIN 1 | Authors: | Calvino, F.R, Kharde, S, Wild, K, Bange, G, Sinning, I. | Deposit date: | 2015-01-21 | Release date: | 2015-04-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.398 Å) | Cite: | Symportin 1 Chaperones 5S Rnp Assembly During Ribosome Biogenesis by Occupying an Essential Rrna-Binding Site. Nat.Commun., 6, 2015
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8WHY
| Cryo- EM structure of Mycobacterium smegmatis 50S ribosomal subunit (body 1) of 70S ribosome and RafH. | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Kumar, N, Sharma, S, Kaushal, P.S. | Deposit date: | 2023-09-23 | Release date: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
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5T5H
| Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit | Descriptor: | 40S ribosomal protein L14, 5.8S rRNA, 5S rRNA, ... | Authors: | Liu, Z, Gutierrez-Vargas, C, Wei, J, Grassucci, R.A, Ramesh, M, Espina, N, Sun, M, Tutuncuoglu, B, Madison-Antenucci, S, Woolford Jr, J.L, Tong, L, Frank, J. | Deposit date: | 2016-08-31 | Release date: | 2016-10-12 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit. Proc.Natl.Acad.Sci.USA, 113, 2016
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6X50
| Mfd-bound E.coli RNA polymerase elongation complex - V state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Llewelyn, E, Chen, J, Kang, J.Y, Darst, S.A. | Deposit date: | 2020-05-24 | Release date: | 2021-02-03 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for transcription complex disruption by the Mfd translocase. Elife, 10, 2021
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4R71
| Structure of the Qbeta holoenzyme complex in the P1211 crystal form | Descriptor: | 30S ribosomal protein S1, Elongation factor Ts, Elongation factor Tu, ... | Authors: | Gytz, H, Seweryn, P, Kutlubaeva, Z, Chetverin, A.B, Brodersen, D.E, Knudsen, C.R. | Deposit date: | 2014-08-26 | Release date: | 2015-09-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | Structural basis for RNA-genome recognition during bacteriophage Q beta replication. Nucleic Acids Res., 43, 2015
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