1OE4
 
 | | Xenopus SMUG1, an anti-mutator uracil-DNA Glycosylase | | Descriptor: | 5'-D(*CP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*G)-3', 5'-D(*CP*GP*GP*AP*CP*TP*3DR*AP*CP*GP*GP*G)-3', GLYCEROL, ... | | Authors: | Wibley, J.E.A, Pearl, L.H. | | Deposit date: | 2003-03-19 | | Release date: | 2003-07-11 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure and Specificity of the Vertebrate Anti-Mutator Uracil-DNA Glycosylase Smug1
Mol.Cell, 11, 2003
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4ZBY
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1OKB
 | | crystal structure of Uracil-DNA glycosylase from Atlantic cod (Gadus morhua) | | Descriptor: | CHLORIDE ION, GLYCEROL, URACIL-DNA GLYCOSYLASE | | Authors: | Leiros, I, Moe, E, Lanes, O, Smalas, A.O, Willassen, N.P. | | Deposit date: | 2003-07-21 | | Release date: | 2004-04-05 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The Crystal Structure of Uracil-DNA Glycosylase from Atlantic Cod (Gadus Morhua) Reveals Cold-Adaptation Features
Acta Crystallogr.,Sect.D, 59, 2003
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4Z7B
 | | Structure of the enzyme-product complex resulting from TDG action on a GfC mismatch | | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ... | | Authors: | Pozharski, E, Malik, S.S, Drohat, A.C. | | Deposit date: | 2015-04-07 | | Release date: | 2015-09-16 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
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4ZBX
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1OE6
 | | Xenopus SMUG1, an anti-mutator uracil-DNA Glycosylase | | Descriptor: | 5'-D(*CP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*G)-3', 5'-D(*CP*GP*GP*AP*CP*TP*3DRP*AP*CP*GP*GP*G)-3', 5-HYDROXYMETHYL URACIL, ... | | Authors: | Wibley, J.E.A, Pearl, L.H. | | Deposit date: | 2003-03-19 | | Release date: | 2003-07-11 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure and Specificity of the Vertebrate Anti-Mutator Uracil-DNA Glycosylase Smug1
Mol.Cell, 11, 2003
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4ZBZ
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4Z3A
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1MUG
 | | G:T/U MISMATCH-SPECIFIC DNA GLYCOSYLASE FROM E.COLI | | Descriptor: | PROTEIN (G:T/U SPECIFIC DNA GLYCOSYLASE), SULFATE ION | | Authors: | Barrett, T.E, Savva, R, Panayotou, G, Brown, T, Barlow, T, Jiricny, J, Pearl, L.H. | | Deposit date: | 1998-07-10 | | Release date: | 1998-07-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions.
Cell(Cambridge,Mass.), 92, 1998
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1OE5
 | | Xenopus SMUG1, an anti-mutator uracil-DNA Glycosylase | | Descriptor: | 2'-DEOXYURIDINE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-D(*CP*3DRP*GP*GP*AP*CP*TP*3DRP*AP*CP*GP*GP*GP)-3', ... | | Authors: | Wibley, J.E.A, Pearl, L.H. | | Deposit date: | 2003-03-19 | | Release date: | 2003-07-11 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure and Specificity of the Vertebrate Anti-Mutator Uracil-DNA Glycosylase Smug1
Mol.Cell, 11, 2003
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1Q3F
 | | Uracil DNA glycosylase bound to a cationic 1-aza-2'-deoxyribose-containing DNA | | Descriptor: | 5'-D(*AP*AP*AP*GP*AP*TP*AP*AP*CP*A)-3', 5'-D(*TP*GP*TP*(NRI)P*AP*TP*CP*TP*T)-3', PHOSPHATE ION, ... | | Authors: | Bianchet, M.A, Seiple, L.A, Jiang, Y.L, Ichikawa, Y, Amzel, L.M, Stivers, J.T. | | Deposit date: | 2003-07-29 | | Release date: | 2004-03-23 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Electrostatic guidance of glycosyl cation migration along the reaction coordinate of uracil DNA glycosylase.
Biochemistry, 42, 2003
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1MWI
 | | Crystal structure of a MUG-DNA product complex | | Descriptor: | 5'-D(*CP*GP*CP*GP*AP*GP*(AAB)P*TP*CP*GP*CP*G)-3', G/U mismatch-specific DNA glycosylase | | Authors: | Barrett, T.E, Savva, R, Panayotou, G, Brown, T, Barlow, T, Jiricny, J, Pearl, L.H. | | Deposit date: | 2002-09-30 | | Release date: | 2002-10-04 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions.
Cell(Cambridge,Mass.), 92, 1998
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2C56
 | | A comparative study of uracil DNA glycosylases from human and herpes simplex virus type 1 | | Descriptor: | URACIL DNA GLYCOSYLASE, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | Authors: | Krusong, K, Carpenter, E.P, Bellamy, S.R.W, Savva, R, Baldwin, G.S. | | Deposit date: | 2005-10-26 | | Release date: | 2005-11-28 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A Comparative Study of Uracil-DNA Glycosylases from Human and Herpes Simplex Virus Type 1.
J.Biol.Chem., 281, 2006
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2C53
 | | A comparative study of uracil DNA glycosylases from human and herpes simplex virus type 1 | | Descriptor: | 2'-DEOXYURIDINE, GLYCEROL, URACIL DNA GLYCOSYLASE | | Authors: | Krusong, K, Carpenter, E.P, Bellmy, S.R.W, Savva, R, Baldwin, G.S. | | Deposit date: | 2005-10-25 | | Release date: | 2005-11-28 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A Comparative Study of Uracil-DNA Glycosylases from Human and Herpes Simplex Virus Type 1.
J.Biol.Chem., 281, 2006
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3TR7
 | | Structure of a uracil-DNA glycosylase (ung) from Coxiella burnetii | | Descriptor: | Uracil-DNA glycosylase | | Authors: | Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | | Deposit date: | 2011-09-09 | | Release date: | 2011-09-21 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.1958 Å) | | Cite: | Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
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2BOO
 | | The crystal structure of Uracil-DNA N-Glycosylase (UNG) from Deinococcus radiodurans. | | Descriptor: | NITRATE ION, URACIL-DNA GLYCOSYLASE | | Authors: | Leiros, I, Moe, E, Smalas, A.O, McSweeney, S. | | Deposit date: | 2005-04-13 | | Release date: | 2005-07-27 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of the Uracil-DNA N-Glycosylase (Ung) from Deinococcus Radiodurans.
Acta Crystallogr.,Sect.D, 61, 2005
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2C2P
 | | The crystal structure of mismatch specific uracil-DNA glycosylase (MUG) from Deinococcus radiodurans | | Descriptor: | ACETATE ION, G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE | | Authors: | Moe, E, Leiros, I, Smalas, A.O, McSweeney, S. | | Deposit date: | 2005-09-29 | | Release date: | 2005-10-18 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The Crystal Structure of Mismatch Specific Uracil-DNA Glycosylase (Mug) from Deinococcus Radiodurans Reveals a Novel Catalytic Residue and Broad Substrate Specificity
J.Biol.Chem., 281, 2006
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2C2Q
 | | The crystal structure of mismatch specific uracil-DNA glycosylase (MUG) from Deinococcus radiodurans. Inactive mutant Asp93Ala. | | Descriptor: | ACETATE ION, G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE | | Authors: | Moe, E, Leiros, I, Smalas, A.O, McSweeney, S. | | Deposit date: | 2005-09-29 | | Release date: | 2005-10-18 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Crystal Structure of Mismatch Specific Uracil-DNA Glycosylase (Mug) from Deinococcus Radiodurans Reveals a Novel Catalytic Residue and Broad Substrate Specificity
J.Biol.Chem., 281, 2006
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3UFJ
 | | Human Thymine DNA Glycosylase Bound to Substrate Analog 2'-fluoro-2'-deoxyuridine | | Descriptor: | 5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*GP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(UF2)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', G/T mismatch-specific thymine DNA glycosylase | | Authors: | Pozharski, E, Maiti, A, Drohat, A.C. | | Deposit date: | 2011-11-01 | | Release date: | 2012-04-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.967 Å) | | Cite: | Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3UO7
 | | Crystal structure of Human Thymine DNA Glycosylase Bound to Substrate 5-carboxylcytosine | | Descriptor: | 5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*AP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(1CC)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', G/T mismatch-specific thymine DNA glycosylase | | Authors: | Zhang, L, He, C. | | Deposit date: | 2011-11-16 | | Release date: | 2012-02-15 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.002 Å) | | Cite: | Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA.
Nat.Chem.Biol., 8, 2012
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3WDF
 | | Staphylococcus aureus UDG | | Descriptor: | Uracil-DNA glycosylase | | Authors: | Wang, H.C, Ko, T.P, Wang, A.H.J. | | Deposit date: | 2013-06-18 | | Release date: | 2014-02-05 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Staphylococcus aureus protein SAUGI acts as a uracil-DNA glycosylase inhibitor.
Nucleic Acids Res., 42, 2013
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2D3Y
 | | Crystal structure of uracil-DNA glycosylase from Thermus Thermophilus HB8 | | Descriptor: | 2'-DEOXYURIDINE-5'-MONOPHOSPHATE, ACETATE ION, IRON/SULFUR CLUSTER, ... | | Authors: | Kosaka, H, Nakagawa, N, Masui, R, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-10-04 | | Release date: | 2006-10-17 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structure of family 5 uracil-DNA glycosylase bound to DNA.
J.Mol.Biol., 373, 2007
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3UOB
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2DDG
 | | Crystal structure of uracil-DNA glycosylase in complex with AP:G containing DNA | | Descriptor: | 5'-D(*AP*TP*GP*TP*TP*GP*CP*(D1P)P*TP*TP*AP*GP*TP*CP*C)-3', 5'-D(*GP*GP*AP*CP*TP*AP*AP*GP*GP*CP*AP*AP*CP*A)-3', ACETATE ION, ... | | Authors: | Kosaka, H, Nakagawa, N, Masui, R, Hoseki, J, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-01-28 | | Release date: | 2007-02-13 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of family 5 uracil-DNA glycosylase bound to DNA.
J.Mol.Biol., 373, 2007
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2DP6
 | | Crystal structure of uracil-DNA glycosylase in complex with AP:C containing DNA | | Descriptor: | 5'-D(*AP*TP*GP*TP*TP*GP*CP*(D1P)P*TP*TP*AP*GP*TP*CP*C)-3', 5'-D(*GP*GP*AP*CP*TP*AP*AP*CP*GP*CP*AP*AP*CP*A)-3', DIHYDROGENPHOSPHATE ION, ... | | Authors: | Kosaka, H, Nakagawa, N, Masui, R, Kuramitsu, S, Hoseki, J, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-05-07 | | Release date: | 2007-05-22 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of Family 5 Uracil-DNA Glycosylase Bound to DNA Reveals Insights into the Mechanism for Substrate Recognition and Catalysis
To be Published
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