1Q3F

Uracil DNA glycosylase bound to a cationic 1-aza-2'-deoxyribose-containing DNA

Summary for 1Q3F

• Entry DOI: 10.2210/pdb1q3f/pdb
• Related: 1EMH 1SSP
• Descriptor: 5'-D(*TP*GP*TP*(NRI)P*AP*TP*CP*TP*T)-3', 5'-D(*AP*AP*AP*GP*AP*TP*AP*AP*CP*A)-3', Uracil-DNA glycosylase, ... (6 entities in total)
• Functional Keywords: udg, dna repair, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 1: Mitochondrion. Isoform 2: Nucleus: P13051
• Total number of polymer chains: 3
• Total formula weight: 31407.98

Authors

Bianchet, M.A.,Seiple, L.A.,Jiang, Y.L.,Ichikawa, Y.,Amzel, L.M.,Stivers, J.T. (deposition date: 2003-07-29, release date: 2004-03-23, Last modification date: 2023-08-16)

• Primary citation: Bianchet, M.A.,Seiple, L.A.,Jiang, Y.L.,Ichikawa, Y.,Amzel, L.M.,Stivers, J.T.; Electrostatic guidance of glycosyl cation migration along the reaction coordinate of uracil DNA glycosylase.; Biochemistry, 42:12455-12460, 2003; PubMed: 14580190; DOI: 10.1021/bi035372+

Experimental method

X-RAY DIFFRACTION (1.9 Å)