2DP6

Crystal structure of uracil-DNA glycosylase in complex with AP:C containing DNA

Summary for 2DP6

• Entry DOI: 10.2210/pdb2dp6/pdb
• Related: 2D3Y 2DDG 2DEM
• Descriptor: 5'-D(*AP*TP*GP*TP*TP*GP*CP*(D1P)P*TP*TP*AP*GP*TP*CP*C)-3', 5'-D(*GP*GP*AP*CP*TP*AP*AP*CP*GP*CP*AP*AP*CP*A)-3', uracil-DNA glycosylase, ... (8 entities in total)
• Functional Keywords: base excision repair, uracil-dna glycosylase, iron/sulfer cluster, dna complex, thermophile, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, hydrolase-dna complex, hydrolase/dna
• Biological source: Thermus thermophilus
• Total number of polymer chains: 3
• Total formula weight: 33840.70

Authors

Kosaka, H.,Nakagawa, N.,Masui, R.,Kuramitsu, S.,Hoseki, J.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2006-05-07, release date: 2007-05-22, Last modification date: 2023-10-25)

• Primary citation: Kosaka, H.,Nakagawa, N.,Masui, R.,Kuramitsu, S.; Structure of Family 5 Uracil-DNA Glycosylase Bound to DNA Reveals Insights into the Mechanism for Substrate Recognition and Catalysis; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)