7WEG
| Complex structure of PDZD7 and FCHSD2 | Descriptor: | FCHSD2, PDZ domain-containing protein 7, ZINC ION | Authors: | Wang, H, Lin, L, Lu, Q. | Deposit date: | 2021-12-23 | Release date: | 2022-11-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Deafness-related protein PDZD7 forms complex with the C-terminal tail of FCHSD2. Biochem.J., 479, 2022
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5VWK
| Crystal structure of human Scribble PDZ1:Beta-PIX complex | Descriptor: | Beta-PIX, Protein scribble homolog, SULFATE ION | Authors: | Lim, K.Y.B, Kvansakul, M. | Deposit date: | 2017-05-22 | Release date: | 2017-11-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX. J. Biol. Chem., 292, 2017
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5VWI
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7X2E
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4G69
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4E35
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6UBH
| Structure of the MM7 Erbin PDZ variant in complex with a high-affinity peptide | Descriptor: | Erbin, SODIUM ION, peptide | Authors: | Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S. | Deposit date: | 2019-09-11 | Release date: | 2020-07-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain. J.Mol.Biol., 433, 2021
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6SPV
| Crystal structure of PDZ1-2 from PSD-95 | Descriptor: | Disks large homolog 4, GLUTATHIONE | Authors: | Rodzli, N, Levy, C.W, Prince, S.M. | Deposit date: | 2019-09-02 | Release date: | 2019-10-02 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | The Dual PDZ Domain from Postsynaptic Density Protein 95 Forms a Scaffold with Peptide Ligand. Biophys.J., 119, 2020
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4F8K
| Molecular analysis of the interaction between the prostacyclin receptor and the first PDZ domain of PDZK1 | Descriptor: | Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Prostacyclin receptor | Authors: | Kocher, O, Birrane, G, Kinsella, B.T, Mulvaney, E.P. | Deposit date: | 2012-05-17 | Release date: | 2013-02-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular Analysis of the Prostacyclin Receptor's Interaction with the PDZ1 Domain of Its Adaptor Protein PDZK1. Plos One, 8, 2013
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5VWC
| Crystal structure of human Scribble PDZ1 domain | Descriptor: | 1,2-ETHANEDIOL, Protein scribble homolog | Authors: | Lim, K.Y.B, Kvansakul, M. | Deposit date: | 2017-05-21 | Release date: | 2017-11-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.911 Å) | Cite: | Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX. J. Biol. Chem., 292, 2017
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5W72
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5WOU
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7XTY
| Crystal Structure of the second PDZ domain from human PTPN13 in complex with APC peptide | Descriptor: | APC-peptide, Tyrosine-protein phosphatase non-receptor type 13 | Authors: | Jing, L.Q, Sun, X.N, Ma, W.H, Zhou, W.J, Wu, D.L. | Deposit date: | 2022-05-18 | Release date: | 2023-05-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Targeting PTPN13 with 11 amino acid peptides of C-terminal APC prevents immune evasion of colorectal cancer to be published
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4GVD
| Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in complex with Syndecan1 Peptide | Descriptor: | 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), CHLORIDE ION, SODIUM ION, ... | Authors: | Liu, X, Shepherd, T.R, Murray, A.M, Xu, Z, Fuentes, E.J. | Deposit date: | 2012-08-30 | Release date: | 2013-03-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics. Structure, 21, 2013
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6V84
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5V6B
| Crystal structure of GIPC1 | Descriptor: | PDZ domain-containing protein GIPC1 | Authors: | Shang, G, Zhang, X. | Deposit date: | 2017-03-16 | Release date: | 2017-05-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex. Elife, 6, 2017
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4H11
| Interaction partners of PSD-93 studied by X-ray crystallography and fluorescent polarization spectroscopy | Descriptor: | ACETATE ION, Disks large homolog 2, SULFATE ION | Authors: | Fiorentini, M, Kastrup, J.S, Gajhede, M. | Deposit date: | 2012-09-10 | Release date: | 2013-04-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy. Acta Crystallogr.,Sect.D, 69, 2013
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4GVC
| Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in complex with phosphorylated Syndecan1 Peptide | Descriptor: | 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), CHLORIDE ION, SODIUM ION, ... | Authors: | Liu, X, Shepherd, T.R, Murray, A.M, Xu, Z, Fuentes, E.J. | Deposit date: | 2012-08-30 | Release date: | 2013-03-13 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics. Structure, 21, 2013
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4E34
| Crystal structure of CFTR Associated Ligand (CAL) PDZ domain bound to iCAL36 (ANSRWPTSII) peptide | Descriptor: | GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, decameric peptide, ... | Authors: | Amacher, J.F, Beck, T, Madden, D.R. | Deposit date: | 2012-03-09 | Release date: | 2012-12-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.395 Å) | Cite: | Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP. J.Biol.Chem., 288, 2013
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4E3B
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4HOP
| Crystal structure of the computationally designed NNOS-Syntrophin complex | Descriptor: | Alpha-1-syntrophin, Nitric oxide synthase, brain | Authors: | Harwood, I.M, Melero, C, Ollikainen, N, Kortemme, T. | Deposit date: | 2012-10-22 | Release date: | 2013-11-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Quantification of the transferability of a designed protein specificity switch reveals extensive epistasis in molecular recognition. Proc.Natl.Acad.Sci.USA, 111, 2014
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3AXA
| Crystal structure of afadin PDZ domain in complex with the C-terminal peptide from nectin-3 | Descriptor: | Afadin, Nectin-3 | Authors: | Fujiwara, Y, Goda, N, Narita, H, Satomura, K, Nakagawa, A, Sakisaka, T, Suzuki, M, Hiroaki, H. | Deposit date: | 2011-03-31 | Release date: | 2012-04-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Crystal structure of afadin PDZ domain-nectin-3 complex shows the structural plasticity of the ligand-binding site. Protein Sci., 24, 2015
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2ZPM
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3B76
| Crystal structure of the third PDZ domain of human ligand-of-numb protein-X (LNX1) in complex with the C-terminal peptide from the coxsackievirus and adenovirus receptor | Descriptor: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase LNX, SODIUM ION | Authors: | Ugochukwu, E, Burgess-Brown, N, Berridge, G, Elkins, J, Bunkoczi, G, Pike, A.C.W, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Gileadi, O, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC) | Deposit date: | 2007-10-30 | Release date: | 2007-11-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of the third PDZ domain of human ligand-of-numb protein-X (LNX1) in complex with the C-terminal peptide from the coxsackievirus and adenovirus receptor. To be Published
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1I92
| STRUCTURAL BASIS OF THE NHERF PDZ1-CFTR INTERACTION | Descriptor: | CHLORIDE ION, NA+/H+ EXCHANGE REGULATORY CO-FACTOR | Authors: | Karthikeyan, S, Leung, T, Ladias, J.A.A. | Deposit date: | 2001-03-16 | Release date: | 2001-06-27 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis of the Na+/H+ exchanger regulatory factor PDZ1 interaction with the carboxyl-terminal region of the cystic fibrosis transmembrane conductance regulator. J.Biol.Chem., 276, 2001
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