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1SP8
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BU of 1sp8 by Molmil
4-Hydroxyphenylpyruvate Dioxygenase
Descriptor: 4-Hydroxyphenylpyruvate Dioxygenase, FE (II) ION
Authors:Fritze, I.M, Linden, L, Freigang, J, Auerbach, G, Huber, R, Steinbacher, S.
Deposit date:2004-03-16
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structures of Zea mays and Arabidopsis 4-Hydroxyphenylpyruvate Dioxygenase
Plant physiol., 134, 2004
3MI6
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BU of 3mi6 by Molmil
Crystal structure of the alpha-galactosidase from Lactobacillus brevis, Northeast Structural Genomics Consortium Target LbR11.
Descriptor: Alpha-galactosidase
Authors:Vorobiev, S, Chen, Y, Seetharaman, J, Belote, R, Sahdev, S, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-04-09
Release date:2010-04-28
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:Crystal structure of the alpha-galactosidase from Lactobacillus brevis.
To be Published
7T3D
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BU of 7t3d by Molmil
CryoEM map of anchor 222-1C06 Fab and lateral patch 2B05 Fab binding H1 HA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 222-1C06 mAb heavy chain, ...
Authors:Han, J, Ward, A.B.
Deposit date:2021-12-07
Release date:2022-01-12
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Broadly neutralizing antibodies target a haemagglutinin anchor epitope.
Nature, 602, 2022
6Q6P
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BU of 6q6p by Molmil
Antarctic fish cytoglobin 1 from D.mawsoni
Descriptor: Cytoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Giordano, D, Pesce, A, Vermeylen, S, Abbruzzetti, S, Nardini, M, Marchesani, F, Berghmans, H, Seira, C, Bruno, S, Luque, F.J, di Prisco, G, Ascenzi, P, Dewilde, S, Bolognesi, M, Viappiani, C, Verde, C.
Deposit date:2018-12-11
Release date:2020-01-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and functional properties of Antarctic fish cytoglobins-1: Cold-reactivity in multi-ligand reactions.
Comput Struct Biotechnol J, 18, 2020
1JF8
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BU of 1jf8 by Molmil
X-ray structure of reduced C10S, C15A arsenate reductase from pI258
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BICARBONATE ION, POTASSIUM ION, ...
Authors:Zegers, I, Martins, J.C, Willem, R, Wyns, L, Messens, J.
Deposit date:2001-06-20
Release date:2001-10-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Arsenate reductase from S. aureus plasmid pI258 is a phosphatase drafted for redox duty.
Nat.Struct.Biol., 8, 2001
5I8Z
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BU of 5i8z by Molmil
Crystal structure of B. pseudomallei FabI in complex with NAD and PT12
Descriptor: 5-HEXYL-2-(4-NITROPHENOXY)PHENOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Hirschbeck, M.W, Eltschkner, S, Tonge, P.J, Kisker, C.
Deposit date:2016-02-19
Release date:2017-02-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.623 Å)
Cite:Rationalizing the Binding Kinetics for the Inhibition of the Burkholderia pseudomallei FabI1 Enoyl-ACP Reductase.
Biochemistry, 56, 2017
1SQA
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BU of 1sqa by Molmil
Substituted 2-Naphthamidine Inhibitors of Urokinase
Descriptor: 6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENYL]-4-(PYRIMIDIN-2-YLAMINO)-2-NAPHTHAMIDE, SULFATE ION, Urokinase-type plasminogen activator
Authors:Wendt, M.D, Geyer, A, McClellan, W.J, Rockway, T.W, Weitzberg, M, Zhao, X, Stewart, K, Nienaber, V, Klinghofer, V, Giranda, V.L.
Deposit date:2004-03-18
Release date:2004-04-27
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interaction with the S1beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
7SV7
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BU of 7sv7 by Molmil
The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Tezacaftor (VX-661)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, Cystic fibrosis transmembrane conductance regulator, ...
Authors:Fiedorczuk, K, Chen, J.
Deposit date:2021-11-18
Release date:2022-01-12
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Mechanism of CFTR correction by type I folding correctors.
Cell, 185, 2022
6Q6T
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BU of 6q6t by Molmil
Crystal structure (orthorombic form) of C36S mutant of thioredoxin h1 from Chlamydomonas reinhardtii
Descriptor: DI(HYDROXYETHYL)ETHER, Thioredoxin H-type
Authors:Fermani, S, Zaffagnini, M, Lemaire, S.D.
Deposit date:2018-12-11
Release date:2019-01-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (0.94 Å)
Cite:Structural and Biochemical Insights into the Reactivity of Thioredoxin h1 fromChlamydomonas reinhardtii.
Antioxidants (Basel), 8, 2019
1SQJ
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BU of 1sqj by Molmil
Crystal Structure Analysis of Oligoxyloglucan reducing-end-specific cellobiohydrolase (OXG-RCBH)
Descriptor: oligoxyloglucan reducing-end-specific cellobiohydrolase
Authors:Yaoi, K, Kondo, H, Noro, N, Suzuki, M, Tsuda, S, Mitsuishi, Y.
Deposit date:2004-03-19
Release date:2004-07-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Tandem Repeat of a Seven-Bladed beta-Propeller Domain in Oligoxyloglucan Reducing-End-Specific Cellobiohydrolase
Structure, 12, 2004
5I92
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BU of 5i92 by Molmil
Crystal structure of Glutamate-1-semialdehyde 2,1- aminomutase (GSA) from Pseudomonas aeruginosa
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Glutamate-1-semialdehyde 2,1-aminomutase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2016-02-19
Release date:2016-03-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of Glutamate-1-semialdehyde 2,1- aminomutase (GSA) from Pseudomonas aeruginosa
To Be Published
1JFF
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BU of 1jff by Molmil
Refined structure of alpha-beta tubulin from zinc-induced sheets stabilized with taxol
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Lowe, J, Li, H, Downing, K.H, Nogales, E.
Deposit date:2001-06-20
Release date:2001-09-19
Last modified:2023-08-16
Method:ELECTRON CRYSTALLOGRAPHY (3.5 Å)
Cite:Refined structure of alpha beta-tubulin at 3.5 A resolution.
J.Mol.Biol., 313, 2001
4KLC
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BU of 4klc by Molmil
E343D/F110A Double mutant of human ferrochelatase
Descriptor: FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, mitochondrial, ...
Authors:Lanzilotta, W.N, Medlock, A.E.
Deposit date:2013-05-07
Release date:2014-06-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:E343D/F110A Double mutant of human ferrochelatase
To be Published
3DB9
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BU of 3db9 by Molmil
Crystal structure of UPF0317 protein Atu3911 from Agrobacterium tumefaciens. NorthEast Strcutural Genomics target AtR186
Descriptor: UPF0317 protein Atu3911
Authors:Seetharaman, J, Abashidze, M, Wang, D, Janjua, H, Owens, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-05-30
Release date:2008-07-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of UPF0317 protein Atu3911 from Agrobacterium tumefaciens. NorthEast Strcutural Genomics target AtR186 (CASP Target)
TO BE PUBLISHED
4KM4
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BU of 4km4 by Molmil
E. coli alkaline phosphatase mutant S102G/R166S in complex with inorganic phosphate
Descriptor: Alkaline phosphatase, PHOSPHATE ION, ZINC ION
Authors:Andrews, L.D, Fenn, T.D, Herschlag, D.
Deposit date:2013-05-08
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ground state destabilization by anionic nucleophiles contributes to the activity of phosphoryl transfer enzymes.
Plos Biol., 11, 2013
1JFW
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BU of 1jfw by Molmil
HOMONUCLEAR AND HETERONUCLEAR 1H-13C NUCLEAR MAGNETIC RESONANCE ASSIGNMENT AND STRUCTURAL CHARACTERIZATION OF A HIV-1 TAT PROTEIN
Descriptor: TAT PROTEIN
Authors:Peloponese, J.M, Gregoire, C, Opi, S, Esquieu, D.
Deposit date:2001-06-22
Release date:2001-08-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:1H-13C nuclear magnetic resonance assignment and structural characterization of HIV-1 Tat protein.
C.R.Acad.Sci.III, 323, 2000
1SR3
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BU of 1sr3 by Molmil
Solution structure of the heme chaperone CcmE of Escherichia coli
Descriptor: APO-CCME
Authors:Enggist, E, Thony-Meyer, L, Guntert, P, Pervushin, K.
Deposit date:2004-03-22
Release date:2004-04-06
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR Structure of the Heme Chaperone Ccme Reveals a Novel Functional Motif
Structure, 10, 2002
5IB3
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BU of 5ib3 by Molmil
Crystal structure of HLA-B*27:05 complexed with the self-peptide pVIPR and Copper
Descriptor: Beta-2-microglobulin, COPPER (II) ION, GLYCEROL, ...
Authors:Janke, R, Ballaschk, M, Schmieder, P, Uchanska-Ziegler, B, Ziegler, A, Loll, B.
Deposit date:2016-02-22
Release date:2017-02-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype.
J.Biol.Chem., 2019
3DBF
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BU of 3dbf by Molmil
Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 562
Descriptor: 4-({1-[3-(3-amino-3-oxopropyl)-5-chlorophenyl]-3-methyl-1H-pyrazolo[4,3-c]pyridin-6-yl}amino)-3-methoxy-N-(1-methylpipe ridin-4-yl)benzamide, Polo-like kinase
Authors:Elling, R.A, Zhu, J, Barr, K.J, Romanowski, M.J.
Deposit date:2008-05-31
Release date:2008-10-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
7T0R
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BU of 7t0r by Molmil
Crystal structure of the anti-CD4 adnectin 6940_B01 as a complex with the extracellular domains of CD4 and ibalizumab fAb
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Adnectin 6940_B01, Ibalizumab Heavy Chain, ...
Authors:Williams, S.P, Concha, N.O, Wensel, D.L, Hong, X.
Deposit date:2021-11-30
Release date:2022-01-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment.
J.Mol.Biol., 434, 2021
7TAT
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BU of 7tat by Molmil
SARS-CoV-2 spike in complex with the S2K146 neutralizing antibody Fab fragment (two receptor-binding domains open)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2K146 Fab heavy chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2021-12-21
Release date:2022-01-12
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry.
Science, 375, 2022
1JGO
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BU of 1jgo by Molmil
The Path of Messenger RNA Through the Ribosome. THIS FILE, 1JGO, CONTAINS THE 30S RIBOSOME SUBUNIT, THREE TRNA, AND MRNA MOLECULES. 50S RIBOSOME SUBUNIT IS IN THE FILE 1GIY
Descriptor: 30S 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Yusupova, G.Z, Yusupov, M.M, Cate, J.H.D, Noller, H.F.
Deposit date:2001-06-26
Release date:2001-07-20
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (5.6 Å)
Cite:The path of messenger RNA through the ribosome.
Cell(Cambridge,Mass.), 106, 2001
5IBH
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BU of 5ibh by Molmil
Crystal structure Mycobacterium tuberculosis CYP121 in complex with inhibitor fragment 26h
Descriptor: 4,4'-(5-{[(1H-imidazol-4-yl)methyl]amino}-1H-pyrazole-3,4-diyl)diphenol, Cytochrome P450 121 CYP121, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Levy, C.
Deposit date:2016-02-22
Release date:2016-04-06
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.0201 Å)
Cite:Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors.
J.Med.Chem., 59, 2016
6Q61
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BU of 6q61 by Molmil
Pore-modulating toxins exploit inherent slow inactivation to block K+ channels
Descriptor: Kunitz-type conkunitzin-S1, SULFATE ION
Authors:Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E.
Deposit date:2018-12-10
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Pore-modulating toxins exploit inherent slow inactivation to block K+channels.
Proc.Natl.Acad.Sci.USA, 116, 2019
3DBR
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BU of 3dbr by Molmil
Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8's E1 (APPBP1-UBA3Arg190Gln-NEDD8Ala72Arg)
Descriptor: NEDD8, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 regulatory subunit, ...
Authors:Souphron, J, Schulman, B.A.
Deposit date:2008-06-02
Release date:2008-08-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1.
Biochemistry, 47, 2008

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